William Blair Investment Management
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William Blair Investment Management’s Twist Bioscience TWST Stock Holding History

William Blair Investment Management’s Portfolio TWST Stock Details TWST Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$250M Sell
5,269,718
-684,711
-11% -$30.7M 0.83% 15
2025
Q4 		$189M Buy
5,954,429
+1,812,146
+44% +$56.5M 0.53% 44
2025
Q3 		$117M Buy
4,142,283
+235,679
+6% +$7.14M 0.3% 91
2025
Q2 		$144M Buy
3,906,604
+99,737
+3% +$3.45M 0.38% 78
2025
Q1 		$149M Buy
3,806,867
+857,144
+29% +$38.6M 0.42% 68
2024
Q4 		$137M Sell
2,949,723
-527,572
-15% -$23.8M 0.33% 95
2024
Q3 		$157M Buy
3,477,295
+292,909
+9% +$13.9M 0.39% 90
2024
Q2 		$157M Sell
3,184,386
-324,816
-9% -$13.2M 0.41% 78
2024
Q1 		$120M Sell
3,509,202
-40,672
-1% -$1.47M 0.31% 95
2023
Q4 		$131M Sell
3,549,874
-23,549
-0.7% -$545K 0.38% 90
2023
Q3 		$72.4M Sell
3,573,423
-42,375
-1% -$931K 0.24% 116
2023
Q2 		$74M Buy
3,615,798
+1,561,277
+76% +$23.4M 0.24% 115
2023
Q1 		$31M Buy
2,054,521
+16,845
+0.8% +$372K 0.11% 215
2022
Q4 		$48.5M Buy
2,037,676
+63,291
+3% +$1.84M 0.19% 122
2022
Q3 		$69.6M Sell
1,974,385
-743,000
-27% -$31.6M 0.28% 106
2022
Q2 		$95M Buy
2,717,385
+1,045,779
+63% +$37M 0.35% 97
2022
Q1 		$82.5M Buy
1,671,606
+65,276
+4% +$3.62M 0.25% 117
2021
Q4 		$124M Buy
1,606,330
+408,746
+34% +$42M 0.34% 99
2021
Q3 		$128M Buy
1,197,584
+491,168
+70% +$56.2M 0.36% 95
2021
Q2 		$94.1M Buy
706,416
+50,456
+8% +$5.87M 0.3% 110
2021
Q1 		$81.2M Sell
655,960
-95,295
-13% -$14.5M 0.26% 111
2020
Q4 		$106M Buy
751,255
+454,483
+153% +$50.4M 0.35% 99
2020
Q3 		$22.5M Sell
296,772
-261,038
-47% -$16.3M 0.09% 183
2020
Q2 		$25.3M Sell
557,810
-127,820
-19% -$4.59M 0.1% 170
2020
Q1 		$21M Buy
+685,630
New +$18.4M 0.1% 173

Other funds holding TWST

Artisan Partners
Artisan Partners Milwaukee, Wisconsin $62.3B AUM 26.25% 1-Year Est. Return
AIM
ARK Investment Management St. Petersburg, Florida $12.9B AUM 64.92% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
EIG
EdgePoint Investment Group Toronto, Ontario, Canada $12.5B AUM 31.7% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return
VPM
Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
Invesco
Invesco Atlanta, Georgia $1.02T AUM 30.18% 1-Year Est. Return
Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
Goldman Sachs
Goldman Sachs New York $871B AUM 31.28% 1-Year Est. Return

William Blair Investment Management's TWST Position: Q1 2026 in Review

William Blair Investment Management reduced its Twist Bioscience (TWST) stake by 11% in Q1 2026, selling an estimated $30.7M and leaving 5,269,718 shares worth $250M. The position accounts for 0.83% of the portfolio, ranked #15.

William Blair Investment Management first reported a position in TWST in Q1 2020 and has held it in 25 quarters since. 280 funds tracked by Wall St. Rank hold TWST as of Q1 2026.

  • William Blair Investment Management held 5,269,718 shares of Twist Bioscience worth $250M as of Q1 2026.
  • William Blair Investment Management sold 684,711 Twist Bioscience shares in Q1 2026, an estimated $30.7M.
  • Twist Bioscience made up 0.83% of William Blair Investment Management's portfolio in Q1 2026, its #15 holding.
  • William Blair Investment Management first reported a position in Twist Bioscience in Q1 2020 and has held it in 25 quarters since.
  • 280 funds tracked by Wall St. Rank held Twist Bioscience as of Q1 2026.

Based on William Blair Investment Management's 13F filing for Q1 2026, filed 8 May 2026.