Two Sigma Advisers’s Milestone Pharmaceuticals MIST Stock Holding History

Two Sigma Advisers’s Portfolio MIST Stock Details MIST Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q1	–	Sell	-619,592	Closed	-$1.25M	–	1287
2025 Q4	$1.25M	Buy	619,592 +385,551	+165%	+$830K	﹤0.01%	1374
2025 Q3	$468K	Buy	+234,041	New	+$412K	﹤0.01%	1789
2025 Q2	–	Sell	-76,000	Closed	-$60.8K	–	2445
2025 Q1	$60.8K	Buy	+76,000	New	+$151K	﹤0.01%	2305
2023 Q3	–	Sell	-25,700	Closed	-$73.2K	–	2499
2023 Q2	$73.2K	Buy	25,700 +11,400	+80%	+$43K	﹤0.01%	2240
2023 Q1	$56.3K	Sell	14,300 -34,800	-71%	-$127K	﹤0.01%	2439
2022 Q4	$194K	Buy	+49,100	New	+$258K	﹤0.01%	2198
2021 Q3	–	Sell	-35,600	Closed	-$196K	–	2587
2021 Q2	$196K	Sell	35,600 -22,500	-39%	-$128K	﹤0.01%	2274
2021 Q1	$336K	Buy	58,100 +5,800	+11%	+$42.5K	﹤0.01%	2181
2020 Q4	$350K	Buy	+52,300	New	+$350K	﹤0.01%	1993
2020 Q3	–	Sell	-20,900	Closed	-$79K	–	2554
2020 Q2	$79K	Buy	+20,900	New	+$67.3K	﹤0.01%	2390

Other funds holding MIST

RTW Investments New York $10B AUM 135.35% 1-Year Est. Return

PBM

Propel Bio Management Los Angeles, California $159M AUM 60.94% 1-Year Est. Return

Two Sigma Investments New York $124B AUM 33.93% 1-Year Est. Return

Goldman Sachs New York $871B AUM 31.28% 1-Year Est. Return

Marshall Wace London, United Kingdom $100B AUM 35.1% 1-Year Est. Return

Millennium Management New York $240B AUM 35.51% 1-Year Est. Return

SAM

Simplify Asset Management Las Vegas, Nevada $7.19B AUM 6.88% 1-Year Est. Return

Point72 Asset Management Stamford, Connecticut $78.1B AUM 55.25% 1-Year Est. Return

Balyasny Asset Management Chicago, Illinois $77.1B AUM 42.89% 1-Year Est. Return

LPC

Lion Point Capital New York $16.7M AUM 119.35% 1-Year Est. Return

Two Sigma Advisers's MIST Position: Q1 2026 in Review

Two Sigma Advisers sold out of Milestone Pharmaceuticals (MIST) in Q1 2026, closing a stake of 619,592 shares — an estimated $1.25M sold.

Two Sigma Advisers first reported a position in MIST in Q2 2020 and held it in 10 quarters. The position peaked at $1.25M in Q4 2025. 86 funds tracked by Wall St. Rank hold MIST as of Q1 2026.

Two Sigma Advisers reported no remaining Milestone Pharmaceuticals position as of Q1 2026 after selling out during the quarter.
Two Sigma Advisers sold 619,592 Milestone Pharmaceuticals shares in Q1 2026, an estimated $1.25M.
Two Sigma Advisers first reported a position in Milestone Pharmaceuticals in Q2 2020 and held it in 10 quarters.
Two Sigma Advisers's Milestone Pharmaceuticals position peaked at $1.25M in Q4 2025.
86 funds tracked by Wall St. Rank held Milestone Pharmaceuticals as of Q1 2026.

Based on Two Sigma Advisers's 13F filing for Q1 2026.