Teacher Retirement System of Texas
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Teacher Retirement System of Texas’s Spyre Therapeutics SYRE Stock Holding History

Teacher Retirement System of Texas’s Portfolio SYRE Stock Details SYRE Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$582K Buy
6,554
+274
+4% +$20K ﹤0.01% 1114
2026
Q1 		$317K Sell
6,280
-893
-12% -$33.7K ﹤0.01% 1259
2025
Q4 		$235K Buy
+7,173
New +$187K ﹤0.01% 1493
2025
Q1 		– Sell
-10,383
Closed -$242K – 2130
2024
Q4 		$242K Buy
+10,383
New +$304K ﹤0.01% 1440

Other funds holding SYRE

Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
PA
Perceptive Advisors New York $6.66B AUM 360.84% 1-Year Est. Return
RI
RTW Investments New York $11.7B AUM 174.13% 1-Year Est. Return
PBA
Paradigm Biocapital Advisors New York $5.34B AUM 380.18% 1-Year Est. Return
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
State Street
State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return
VA
VR Adviser New York $3.3B AUM 525.74% 1-Year Est. Return
T. Rowe Price Associates
T. Rowe Price Associates Baltimore, Maryland $999B AUM 46.22% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $17.3B AUM 211.34% 1-Year Est. Return

Teacher Retirement System of Texas's SYRE Position: Q2 2026 in Review

Teacher Retirement System of Texas increased its Spyre Therapeutics (SYRE) stake by 4.4% in Q2 2026, buying an estimated $20K and bringing the position to 6,554 shares worth $582K. The position accounts for ﹤0.01% of the portfolio, ranked #1114.

Teacher Retirement System of Texas first reported a position in SYRE in Q4 2024 and has held it in 4 quarters since. 265 funds tracked by Wall St. Rank hold SYRE as of Q2 2026.

  • Teacher Retirement System of Texas held 6,554 shares of Spyre Therapeutics worth $582K as of Q2 2026.
  • Teacher Retirement System of Texas bought 274 Spyre Therapeutics shares in Q2 2026, an estimated $20K.
  • Spyre Therapeutics made up ﹤0.01% of Teacher Retirement System of Texas's portfolio in Q2 2026, its #1114 holding.
  • Teacher Retirement System of Texas first reported a position in Spyre Therapeutics in Q4 2024 and has held it in 4 quarters since.
  • 265 funds tracked by Wall St. Rank held Spyre Therapeutics as of Q2 2026.

Based on Teacher Retirement System of Texas's 13F filing for Q2 2026, filed 14 Aug 2026.