SL

Siren LLC Portfolio holdings

AUM $2.56B
1-Year Est. Return 159.09%
This Fund
S&P 500
This Quarter Est. Return
1 Year Est. Return
+159.09%
3 Year Est. Return
5 Year Est. Return
10 Year Est. Return
AUM
$1.93B
AUM Growth
+$160M
Cap. Flow
Cap. Flow %
Top 10 Hldgs %
Holding
131
New
Increased
Reduced
Closed

Top Buys

1
+$24M
2
+$20.2M
3
+$19.2M
4
BCAX
Bicara Therapeutics
BCAX
+$18.1M
5
AKRO
Akero Therapeutics
AKRO
+$17M

Top Sells

1
+$64.3M
2
+$21.8M
3
+$15.9M
4
SMMT icon
Summit Therapeutics
SMMT
+$13.4M
5
NAMS icon
NewAmsterdam Pharma
NAMS
+$13M

Sector Composition

1 Healthcare 90.42%
2 Technology 4.93%
3 Communication Services 2.51%
4 Consumer Discretionary 1.07%
5 Real Estate 0.77%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
MLTX icon
26
MoonLake Immunotherapeutics
MLTX
$1.13B
$24M 1.24%
+508,267
SEPN
27
Septerna Inc
SEPN
$1.16B
$23.3M 1.2%
2,202,514
NAMS icon
28
NewAmsterdam Pharma
NAMS
$3.68B
$21.6M 1.12%
1,194,240
-717,790
TRVI icon
29
Trevi Therapeutics
TRVI
$1.29B
$21.5M 1.11%
3,938,793
+1,075,000
TNGX icon
30
Tango Therapeutics
TNGX
$1.59B
$17.2M 0.89%
3,364,814
+799,472
AKRO
31
DELISTED
Akero Therapeutics
AKRO
$17M 0.88%
+318,647
SLN
32
Silence Therapeutics
SLN
$261M
$16.9M 0.87%
2,911,438
+121,605
AVBP icon
33
ArriVent BioPharma
AVBP
$971M
$15.2M 0.79%
+700,000
BCYC
34
Bicycle Therapeutics
BCYC
$486M
$14M 0.72%
2,012,752
+200,000
RCUS icon
35
Arcus Biosciences
RCUS
$2.77B
$13.1M 0.68%
1,612,077
IHS icon
36
IHS Holding
IHS
$2.63B
$13.1M 0.68%
2,357,520
AMZN icon
37
Amazon
AMZN
$2.55T
$12.4M 0.64%
56,500
DNLI icon
38
Denali Therapeutics
DNLI
$3.22B
$11.5M 0.59%
821,513
ERAS icon
39
Erasca
ERAS
$3.01B
$11.1M 0.58%
8,757,249
ORIC icon
40
Oric Pharmaceuticals
ORIC
$1.2B
$10.2M 0.53%
1,007,575
RELY icon
41
Remitly
RELY
$2.92B
$9.67M 0.5%
515,449
+25,000
PCVX icon
42
Vaxcyte
PCVX
$7.08B
$9.61M 0.5%
295,543
CRWD icon
43
CrowdStrike
CRWD
$122B
$9.42M 0.49%
18,500
-6,500
CGEM icon
44
Cullinan Oncology
CGEM
$683M
$8.99M 0.47%
1,193,410
GOOGL icon
45
Alphabet (Google) Class A
GOOGL
$4.07T
$8.93M 0.46%
50,703
UPB
46
Upstream Bio Inc
UPB
$1.64B
$8.66M 0.45%
788,450
SEER icon
47
Seer Inc
SEER
$109M
$8.56M 0.44%
4,000,000
MSFT icon
48
Microsoft
MSFT
$3.55T
$8.03M 0.42%
16,150
-12,350
NVDA icon
49
NVIDIA
NVDA
$4.56T
$7.9M 0.41%
49,985
+5,553
IONQ icon
50
IonQ
IONQ
$15.5B
$7.3M 0.38%
170,000
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