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Siren LLC’s Dyne Therapeutics DYN Stock Holding History

Siren LLC’s Portfolio DYN Stock Details DYN Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$40.4M Sell
2,229,125
-1,273,816
-36% -$22M 1.12% 26
2025
Q4 		$68.5M Sell
3,502,941
-1,226,233
-26% -$23.2M 2.04% 16
2025
Q3 		$59.8M Sell
4,729,174
-107,263
-2% -$1.22M 2.34% 10
2025
Q2 		$46M Buy
4,836,437
+2,118,450
+78% +$23.3M 2.38% 7
2025
Q1 		$28.4M Buy
2,717,987
+1,370,531
+102% +$19.6M 1.6% 19
2024
Q4 		$31.7M Buy
1,347,456
+212,792
+19% +$6.29M 1.4% 22
2024
Q3 		$40.8M Buy
+1,134,664
New +$45.2M 2.04% 17

Other funds holding DYN

T. Rowe Price Investment Management
T. Rowe Price Investment Management Baltimore, Maryland $145B AUM 22.78% 1-Year Est. Return
Janus Henderson Group
Janus Henderson Group London, United Kingdom $209B AUM 37.72% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
AVLSA
Atlas Venture Life Science Advisors Cambridge, Massachusetts $790M AUM 223.66% 1-Year Est. Return
Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
OAG
Orbis Allan Gray Hamilton, Bermuda $23.7B AUM 65.43% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
PA
Perceptive Advisors New York $5.12B AUM 314.02% 1-Year Est. Return
FIS
FCPM III Services Naarden, Netherlands $722M AUM 73.61% 1-Year Est. Return

Siren LLC's DYN Position: Q1 2026 in Review

Siren LLC reduced its Dyne Therapeutics (DYN) stake by 36% in Q1 2026, selling an estimated $22M and leaving 2,229,125 shares worth $40.4M. The position accounts for 1.12% of the portfolio, ranked #26.

Siren LLC first reported a position in DYN in Q3 2024 and has held it in 7 quarters since. The position peaked at $68.5M in Q4 2025. 227 funds tracked by Wall St. Rank hold DYN as of Q1 2026.

  • Siren LLC held 2,229,125 shares of Dyne Therapeutics worth $40.4M as of Q1 2026.
  • Siren LLC sold 1,273,816 Dyne Therapeutics shares in Q1 2026, an estimated $22M.
  • Dyne Therapeutics made up 1.12% of Siren LLC's portfolio in Q1 2026, its #26 holding.
  • Siren LLC first reported a position in Dyne Therapeutics in Q3 2024 and has held it in 7 quarters since.
  • Siren LLC's Dyne Therapeutics position peaked at $68.5M in Q4 2025.
  • 227 funds tracked by Wall St. Rank held Dyne Therapeutics as of Q1 2026.

Based on Siren LLC's 13F filing for Q1 2026, filed 14 May 2026.