SL

Siren LLC Portfolio holdings

AUM $2.56B
1-Year Est. Return 159.09%
This Quarter Est. Return
1 Year Est. Return
+159.09%
3 Year Est. Return
5 Year Est. Return
10 Year Est. Return
AUM
$2.56B
AUM Growth
+$624M
Cap. Flow
Cap. Flow %
Top 10 Hldgs %
Holding
133
New
Increased
Reduced
Closed

Top Buys

1 +$45.8M
2 +$28.8M
3 +$21.2M
4
RAPP
Rapport Therapeutics
RAPP
+$20M
5
RELY icon
Remitly
RELY
+$18M

Top Sells

1 +$44.9M
2 +$25.8M
3 +$24M
4
AKRO
Akero Therapeutics
AKRO
+$17M
5
TRVI icon
Trevi Therapeutics
TRVI
+$12.8M

Sector Composition

1 Healthcare 91.03%
2 Technology 5.1%
3 Communication Services 1.94%
4 Consumer Discretionary 0.86%
5 Real Estate 0.74%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
SLNO icon
26
Soleno Therapeutics
SLNO
$2.79B
$31.6M 1.24%
467,342
RAPP
27
Rapport Therapeutics
RAPP
$1.44B
$31.3M 1.22%
1,053,469
+675,000
GPCR icon
28
Structure Therapeutics
GPCR
$4.64B
$28.8M 1.12%
+1,026,811
WVE icon
29
Wave Life Sciences
WVE
$3.08B
$27.1M 1.06%
3,696,322
RELY icon
30
Remitly
RELY
$3.06B
$26.4M 1.03%
1,618,271
+1,102,822
COGT icon
31
Cogent Biosciences
COGT
$6.46B
$24.8M 0.97%
1,724,279
+869,900
TRVI icon
32
Trevi Therapeutics
TRVI
$1.64B
$23.2M 0.91%
2,536,867
-1,401,926
NAMS icon
33
NewAmsterdam Pharma
NAMS
$4.22B
$21.8M 0.85%
765,705
-428,535
KRRO icon
34
Korro Bio
KRRO
$77.5M
$20.1M 0.78%
418,833
ERAS icon
35
Erasca
ERAS
$1.02B
$19.1M 0.75%
8,757,249
IHS icon
36
IHS Holding
IHS
$2.47B
$16.1M 0.63%
2,357,520
QURE icon
37
uniQure
QURE
$1.22B
$16.1M 0.63%
+275,200
BCYC
38
Bicycle Therapeutics
BCYC
$517M
$15.6M 0.61%
2,012,752
SLN
39
Silence Therapeutics
SLN
$299M
$15.1M 0.59%
2,911,438
RAPT icon
40
RAPT Therapeutics
RAPT
$1.02B
$15M 0.59%
+580,466
UPB
41
Upstream Bio Inc
UPB
$1.47B
$14.8M 0.58%
788,450
GOSS icon
42
Gossamer Bio
GOSS
$833M
$13.7M 0.54%
5,208,968
AVBP icon
43
ArriVent BioPharma
AVBP
$1.01B
$12.9M 0.51%
700,000
AMZN icon
44
Amazon
AMZN
$2.42T
$12.8M 0.5%
58,500
+2,000
ORIC icon
45
Oric Pharmaceuticals
ORIC
$914M
$12.1M 0.47%
1,007,575
DNLI icon
46
Denali Therapeutics
DNLI
$2.81B
$11.9M 0.47%
821,513
IONQ icon
47
IonQ
IONQ
$17.8B
$10.5M 0.41%
170,000
SION
48
Sionna Therapeutics
SION
$1.91B
$9.56M 0.37%
325,000
CRWD icon
49
CrowdStrike
CRWD
$127B
$9.07M 0.35%
18,500
MSFT icon
50
Microsoft
MSFT
$3.56T
$8.88M 0.35%
17,150
+1,000