SL
Siren LLC Portfolio holdings
AUM
$1.93B
1-Year Return
118.08%
This Quarter Return
+18.65%
1 Year Return
+118.08%
3 Year Return
–
5 Year Return
–
10 Year Return
–
AUM
$1.93B
AUM Growth
+$160M
(+9%)
Cap. Flow
-$12.9M
Cap. Flow
% of AUM
-0.67%
Top 10 Holdings %
Top 10 Hldgs %
48.49%
Holding
131
New
15
Increased
21
Reduced
19
Closed
21
Top Buys
| 1 |
MoonLake Immunotherapeutics
MLTX
|
$24M |
| 2 |
Dyne Therapeutics
DYN
|
$20.2M |
| 3 |
Edgewise Therapeutics
EWTX
|
$19.2M |
| 4 |
BCAX
Bicara Therapeutics Inc. Common Stock
BCAX
|
$18.1M |
| 5 |
Akero Therapeutics
AKRO
|
$17M |
Top Sells
| 1 |
BPMC
Blueprint Medicines
BPMC
|
$64.3M |
| 2 |
Soleno Therapeutics
SLNO
|
$21.8M |
| 3 |
Prothena Corp
PRTA
|
$15.9M |
| 4 |
Summit Therapeutics
SMMT
|
$13.4M |
| 5 |
NewAmsterdam Pharma
NAMS
|
$13M |
Sector Composition
| 1 | Healthcare | 90.42% |
| 2 | Technology | 4.93% |
| 3 | Communication Services | 2.51% |
| 4 | Consumer Discretionary | 1.07% |
| 5 | Real Estate | 0.77% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Shares Change % | Capital Flow | |
|---|---|---|---|---|---|---|
|
26
MoonLake Immunotherapeutics
MLTX
$3.79B
| $24M | 1.24% |
+508,267
| New | +$24M |
|
|
SEPN
27
Septerna, Inc. Common Stock
SEPN
$630M
| $23.3M | 1.2% |
2,202,514
| – | – |
|
|
28
NewAmsterdam Pharma
NAMS
$2.89B
| $21.6M | 1.12% |
1,194,240
-717,790
| -38% | -$13M |
|
29
Trevi Therapeutics
TRVI
$880M
| $21.5M | 1.11% |
3,938,793
+1,075,000
| +38% | +$5.88M |
|
30
Tango Therapeutics
TNGX
$760M
| $17.2M | 0.89% |
3,364,814
+799,472
| +31% | +$4.09M |
|
|
31
Akero Therapeutics
AKRO
$3.52B
| $17M | 0.88% |
+318,647
| New | +$17M |
|
|
SLN
32
Silence Therapeutics
SLN
$247M
| $16.9M | 0.87% |
2,911,438
+121,605
| +4% | +$705K |
|
33
ArriVent BioPharma
AVBP
$792M
| $15.2M | 0.79% |
+700,000
| New | +$15.2M |
|
|
BCYC
34
Bicycle Therapeutics
BCYC
$483M
| $14M | 0.72% |
2,012,752
+200,000
| +11% | +$1.39M |
|
35
Arcus Biosciences
RCUS
$1.23B
| $13.1M | 0.68% |
1,612,077
| – | – |
|
36
IHS Holding
IHS
$2.42B
| $13.1M | 0.68% |
2,357,520
| – | – |
|
37
Amazon
AMZN
$2.51T
| $12.4M | 0.64% |
56,500
| – | – |
|
38
Denali Therapeutics
DNLI
$2.16B
| $11.5M | 0.59% |
821,513
| – | – |
|
39
Erasca
ERAS
$420M
| $11.1M | 0.58% |
8,757,249
| – | – |
|
40
Oric Pharmaceuticals
ORIC
$1.05B
| $10.2M | 0.53% |
1,007,575
| – | – |
|
41
Remitly
RELY
$4.06B
| $9.67M | 0.5% |
515,449
+25,000
| +5% | +$469K |
|
42
Vaxcyte
PCVX
$4.17B
| $9.61M | 0.5% |
295,543
| – | – |
|
43
CrowdStrike
CRWD
$104B
| $9.42M | 0.49% |
18,500
-6,500
| -26% | -$3.31M |
|
44
Cullinan Oncology
CGEM
$408M
| $8.99M | 0.47% |
1,193,410
| – | – |
|
45
Alphabet (Google) Class A
GOOGL
$2.81T
| $8.93M | 0.46% |
50,703
| – | – |
|
|
UPB
46
Upstream Bio, Inc. Common Stock
UPB
$1.06B
| $8.66M | 0.45% |
788,450
| – | – |
|
47
Seer Inc
SEER
$113M
| $8.56M | 0.44% |
4,000,000
| – | – |
|
48
Microsoft
MSFT
$3.78T
| $8.03M | 0.42% |
16,150
-12,350
| -43% | -$6.14M |
|
49
NVIDIA
NVDA
$4.18T
| $7.9M | 0.41% |
49,985
+5,553
| +12% | +$877K |
|
50
IonQ
IONQ
$12.5B
| $7.3M | 0.38% |
170,000
| – | – |
|