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Sio Capital Management Portfolio holdings

AUM $697M
1-Year Est. Return 79.73%
This Fund
S&P 500
This Quarter Est. Return
-12.87%
1 Year Est. Return
+79.73%
3 Year Est. Return
+576.62%
5 Year Est. Return
+422.76%
10 Year Est. Return
+2,506.65%
AUM
$266M
AUM Growth
-$36M
Cap. Flow
+$4.9M
Cap. Flow %
1.84%
Top 10 Hldgs %
54.75%
Holding
84
New
18
Increased
15
Reduced
8
Closed
22

Top Buys

Rank Stock Value
1
OGN icon
Organon & Co
OGN
+$20.1M
2
COR icon
Cencora
COR
+$15.3M
3
BCYC
Bicycle Therapeutics
BCYC
+$13.4M
4
HCA icon
HCA Healthcare
HCA
+$13.3M
5
MDT icon
Medtronic
MDT
+$8.11M

Top Sells

Rank Stock Value
1
MRK icon
Merck
MRK
+$16M
2
SNY icon
Sanofi
SNY
+$15.4M
3
LH icon
Labcorp
LH
+$13M
4
MCK icon
McKesson
MCK
+$10.6M
5
LKFT
Lakefront Biotherapeutics American Depositary Shares
LKFT
+$9.1M

Sector Composition

Rank Sector Weight
1 Healthcare 83.9%
2 Financials 8.53%
3 Consumer Staples 1.75%
4 Industrials 0.18%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
VREX icon
76
Varex Imaging
VREX
$502M
– –
-315,486
Closed -$6.72M
VRTX icon
77
CALL
Vertex Pharmaceuticals
VRTX
$119B
– –
-58,500
Closed -$15.3M
VRTX icon
78
PUT
Vertex Pharmaceuticals
VRTX
$119B
– –
-133,000
Closed -$34.7M
SYRS
79
DELISTED
Syros Pharmaceuticals, Inc. Common Stock
SYRS
– –
-90,291
Closed -$1.07M
VAPO
80
DELISTED
Vapotherm, Inc. Common Stock
VAPO
– –
-44,126
Closed -$4.91M
AYLA
81
DELISTED
Ayala Pharmaceuticals, Inc. Common Stock
AYLA
– –
-60,220
Closed -$240K
LOGC
82
DELISTED
LogicBio Therapeutics, Inc. Common Stock
LOGC
– –
-182,630
Closed -$124K
RDUS
83
DELISTED
Radius Health, Inc.
RDUS
– –
-44,400
Closed -$392K
SRRA
84
DELISTED
Sierra Oncology, Inc. Common Stock
SRRA
– –
-48,768
Closed -$1.56M
1 2 3
4

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Sio Capital Management's Q2 2022 Portfolio in Review

As of Q2 2022, Sio Capital Management held 84 positions worth $266M, down 12% from $302M the previous quarter. Its ten largest holdings account for 55% of the portfolio.

Sio Capital Management's Q2 2022 filing shows 18 new, 15 increased, 8 reduced and 22 closed positions. Its largest new stake was Organon & Co: 574,855 shares worth $19.4M. The largest sale was Merck, an estimated $16M.

By sector, the portfolio is most concentrated in Healthcare at 84% of assets, up from 73% a quarter earlier, followed by Financials and Consumer Staples.

  • Sio Capital Management's largest Q2 2022 buy was Organon & Co: 574,855 shares worth $19.4M.
  • Sio Capital Management added most to Cencora in Q2 2022, an estimated $15.3M increase.
  • Sio Capital Management's biggest Q2 2022 reduction was Cigna, cutting an estimated $3.81M.
  • Sio Capital Management fully exited Merck in Q2 2022, selling an estimated $16M.
  • Sio Capital Management's ten largest holdings make up 55% of its $266M portfolio in Q2 2022.
  • Sio Capital Management opened 18 new positions and closed 22 in Q2 2022.
  • Sio Capital Management's portfolio value fell 12% quarter-over-quarter to $266M.

Based on Sio Capital Management's 13F filing for Q2 2022, filed 15 Aug 2022.