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Sio Capital Management Portfolio holdings

AUM $697M
1-Year Est. Return 79.73%
This Fund
S&P 500
This Quarter Est. Return
-1.39%
1 Year Est. Return
+79.73%
3 Year Est. Return
+576.62%
5 Year Est. Return
+422.76%
10 Year Est. Return
+2,506.65%
AUM
$402M
AUM Growth
-$90.4M
Cap. Flow
-$75.3M
Cap. Flow %
-18.72%
Top 10 Hldgs %
43.57%
Holding
105
New
16
Increased
19
Reduced
23
Closed
32

Top Buys

Rank Stock Value
1
AVAH icon
Aveanna Healthcare
AVAH
+$14.3M
2
AMGN icon
Amgen
AMGN
+$8.61M
3
ITGR icon
Integer Holdings
ITGR
+$6.16M
4
HQY icon
HealthEquity
HQY
+$4.95M
5
SYRS
Syros Pharmaceuticals, Inc. Common Stock
SYRS
+$4.74M

Top Sells

Rank Stock Value
1
CAH icon
Cardinal Health
CAH
+$14.1M
2
CRIS icon
Curis
CRIS
+$11.5M
3
MRK icon
Merck
MRK
+$9.64M
4
ICLR icon
Icon
ICLR
+$9.33M
5
GSK icon
GSK
GSK
+$9.19M

Sector Composition

Rank Sector Weight
1 Healthcare 78.82%
2 Consumer Staples 2.03%
3 Technology 0.88%
4 Industrials 0.61%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
BLRX
76
BioLineRX
BLRX
$11.4M
– –
-68,544
Closed -$7.65M
BNGO icon
77
Bionano Genomics
BNGO
$13M
– –
-40
Closed -$196K
CASI
78
DELISTED
CASI Pharmaceuticals
CASI
– –
-20,343
Closed -$488K
CLRB icon
79
Cellectar Biosciences
CLRB
$20.5M
– –
-7,294
Closed -$3.52M
CVM icon
80
PUT
CEL-SCI Corp
CVM
$22M
– –
-23,190
Closed -$10.6M
EBS icon
81
Emergent Biosolutions
EBS
$380M
– –
-50,000
Closed -$4.65M
ETON icon
82
Eton Pharmaceutcials
ETON
$1.23B
– –
-162,659
Closed -$1.19M
CBIO
83
Crescent Biopharma
CBIO
$553M
– –
-3,555
Closed -$1.07M
GSK icon
84
GSK
GSK
$103B
– –
-206,000
Closed -$9.19M
HROW icon
85
Harrow
HROW
$1.44B
– –
-209,623
Closed -$1.42M
ICLR icon
86
Icon
ICLR
$12.3B
– –
-47,500
Closed -$9.33M
NBP
87
NovaBridge Biosciences American Depositary Shares
NBP
$185M
– –
-15,000
Closed -$727K
IOVA icon
88
Iovance Biotherapeutics
IOVA
$1.92B
– –
-44,430
Closed -$1.41M
KRRO icon
89
PUT
Korro Bio
KRRO
$156M
– –
-3,262
Closed -$1.55M
LLY icon
90
CALL
Eli Lilly
LLY
$997B
– –
-9,600
Closed -$1.79M
LRMR icon
91
Larimar Therapeutics
LRMR
$411M
– –
-187,223
Closed -$2.73M
MRK icon
92
Merck
MRK
$315B
– –
-131,000
Closed -$9.64M
NVAX icon
93
Novavax
NVAX
$1.22B
– –
-25,700
Closed -$4.66M
RAPT
94
DELISTED
RAPT Therapeutics
RAPT
– –
-1,787
Closed -$317K
SNDX icon
95
Syndax Pharmaceuticals
SNDX
$1.7B
– –
-146,142
Closed -$3.27M
TEVA icon
96
Teva Pharmaceuticals
TEVA
$40.1B
– –
-539,947
Closed -$6.23M
ONCT
97
DELISTED
Oncternal Therapeutics, Inc. Common Stock
ONCT
– –
-16,167
Closed -$2.69M
VAPO
98
DELISTED
Vapotherm, Inc. Common Stock
VAPO
– –
-32,283
Closed -$6.2M
RVLP
99
DELISTED
RVL Pharmaceuticals plc Ordinary Shares
RVLP
– –
-519,039
Closed -$1.69M
APTO
100
DELISTED
Aptose Biosciences, Inc.
APTO
– –
-91
Closed -$246K
1 2 3
4
5

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Sio Capital Management's Q2 2021 Portfolio in Review

As of Q2 2021, Sio Capital Management held 105 positions worth $402M, down 18% from $493M the previous quarter. Its ten largest holdings account for 44% of the portfolio.

Sio Capital Management withdrew a net $75.3M in Q2 2021, closing 32 positions and reducing 23 holdings. Its most notable exit was Merck, an estimated $9.64M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 79% of assets, down from 87% a quarter earlier, followed by Consumer Staples and Technology.

Against the trend, Sio Capital Management opened a new position in Aveanna Healthcare worth $14.9M.

  • Sio Capital Management's largest Q2 2021 buy was Aveanna Healthcare: 1,201,607 shares worth $14.9M.
  • Sio Capital Management added most to NeuBase Therapeutics, Inc. Common Stock in Q2 2021, an estimated $2.62M increase.
  • Sio Capital Management's biggest Q2 2021 reduction was Cardinal Health, cutting an estimated $14.1M.
  • Sio Capital Management fully exited Merck in Q2 2021, selling an estimated $9.64M.
  • Sio Capital Management's ten largest holdings make up 44% of its $402M portfolio in Q2 2021.
  • Sio Capital Management opened 16 new positions and closed 32 in Q2 2021.
  • Sio Capital Management's portfolio value fell 18% quarter-over-quarter to $402M.

Based on Sio Capital Management's 13F filing for Q2 2021, filed 16 Aug 2021.