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Sio Capital Management Portfolio holdings

AUM $697M
1-Year Est. Return 79.73%
This Fund
S&P 500
This Quarter Est. Return
-3.76%
1 Year Est. Return
+79.73%
3 Year Est. Return
+576.62%
5 Year Est. Return
+422.76%
10 Year Est. Return
+2,506.65%
AUM
$302M
AUM Growth
-$29.4M
Cap. Flow
-$9.85M
Cap. Flow %
-3.26%
Top 10 Hldgs %
56.17%
Holding
86
New
16
Increased
11
Reduced
16
Closed
20

Top Buys

Rank Stock Value
1
LH icon
Labcorp
LH
+$13.5M
2
SNY icon
Sanofi
SNY
+$10.9M
3
INGN icon
Inogen
INGN
+$9.8M
4
VREX icon
Varex Imaging
VREX
+$8.02M
5
MEDP icon
Medpace
MEDP
+$4.68M

Top Sells

Rank Stock Value
1
CAH icon
Cardinal Health
CAH
+$17.3M
2
GLD icon
SPDR Gold Trust
GLD
+$15.4M
3
CI icon
Cigna
CI
+$12.5M
4
HLF icon
Herbalife
HLF
+$9.88M
5
LKFT
Lakefront Biotherapeutics American Depositary Shares
LKFT
+$7.02M

Sector Composition

Rank Sector Weight
1 Healthcare 73.08%
2 Financials 7.52%
3 Industrials 0.43%
4 Consumer Staples 0%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
NXTC icon
51
NextCure
NXTC
$22.7M
$632K 0.21%
10,833
– –
XFOR icon
52
X4 Pharmaceuticals
XFOR
$393M
$485K 0.16%
9,230
– –
AVAH icon
53
Aveanna Healthcare
AVAH
$2.03B
$449K 0.15%
131,812
-826,437
-86% -$4.49M
VINC
54
DELISTED
Vincerx Pharma, Inc. Common Stock
VINC
$408K 0.14%
5,102
– –
RDUS
55
DELISTED
Radius Health, Inc.
RDUS
$392K 0.13%
+44,400
New +$337K
NYXH
56
Nyxoah
NYXH
$131M
$308K 0.1%
16,110
– –
BHC icon
57
PUT
Bausch Health
BHC
$2.21B
$276K 0.09%
+12,100
New +$296K
AYLA
58
DELISTED
Ayala Pharmaceuticals, Inc. Common Stock
AYLA
$240K 0.08%
60,220
-19,744
-25% -$103K
KOD icon
59
CALL
Kodiak Sciences
KOD
$2.84B
$236K 0.08%
+30,600
New +$1.19M
CMAX
60
DELISTED
CareMax, Inc. Class A Common Stock
CMAX
$230K 0.08%
1,025
– –
RCOR.WS
61
DELISTED
Renovacor, Inc. Warrants, entitling the holder thereof to purchase one-half (1/2) of a share of common stock at a price of $11. 50 per whole share
RCOR.WS
$168K 0.06%
400,000
– –
KZR
62
DELISTED
Kezar Life Sciences
KZR
$152K 0.05%
917
-20,408
-96% -$2.93M
LOGC
63
DELISTED
LogicBio Therapeutics, Inc. Common Stock
LOGC
$124K 0.04%
182,630
– –
HUMAW icon
64
Humacyte Inc Warrant
HUMAW
$1.4M
$97K 0.03%
49,998
– –
NGNE icon
65
Neurogene
NGNE
$710M
$72K 0.02%
1,916
– –
CMAXW
66
DELISTED
CareMax, Inc. Warrant
CMAXW
$20K 0.01%
12,808
– –
AMED
67
DELISTED
Amedisys
AMED
– –
-15,000
Closed -$2.43M
ARDX icon
68
Ardelyx
ARDX
$1.2B
– –
-994,604
Closed -$1.09M
CAH icon
69
Cardinal Health
CAH
$55.7B
– –
-335,271
Closed -$17.3M
CRIS icon
70
CALL
Curis
CRIS
$8.59M
– –
-360
Closed -$685K
DTIL icon
71
Precision BioSciences
DTIL
$191M
– –
-8,572
Closed -$1.9M
GLD icon
72
SPDR Gold Trust
GLD
$138B
– –
-89,890
Closed -$15.4M
HLF icon
73
Herbalife
HLF
$1.19B
– –
-241,437
Closed -$9.88M
ITGR icon
74
Integer Holdings
ITGR
$4.29B
– –
-77,881
Closed -$6.67M
CYPH
75
Cypherpunk Technologies Inc
CYPH
$71.7M
– –
-44,000
Closed -$1.43M
1 2
3
4

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Sio Capital Management's Q1 2022 Portfolio in Review

As of Q1 2022, Sio Capital Management held 86 positions worth $302M, down 8.9% from $332M the previous quarter. Its ten largest holdings account for 56% of the portfolio.

Sio Capital Management withdrew a net $9.85M in Q1 2022, closing 20 positions and reducing 16 holdings. Its most notable exit was Cardinal Health, an estimated $17.3M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 73% of assets, down from 83% a quarter earlier, followed by Financials and Industrials.

Against the trend, Sio Capital Management opened a new position in Labcorp worth $13M.

  • Sio Capital Management's largest Q1 2022 buy was Labcorp: 57,418 shares worth $13M.
  • Sio Capital Management added most to Sanofi in Q1 2022, an estimated $10.9M increase.
  • Sio Capital Management's biggest Q1 2022 reduction was Cigna, cutting an estimated $12.5M.
  • Sio Capital Management fully exited Cardinal Health in Q1 2022, selling an estimated $17.3M.
  • Sio Capital Management's ten largest holdings make up 56% of its $302M portfolio in Q1 2022.
  • Sio Capital Management opened 16 new positions and closed 20 in Q1 2022.
  • Sio Capital Management's portfolio value fell 8.9% quarter-over-quarter to $302M.

Based on Sio Capital Management's 13F filing for Q1 2022, filed 16 May 2022.