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Sio Capital Management Portfolio holdings

AUM $697M
1-Year Est. Return 79.73%
This Fund
S&P 500
This Quarter Est. Return
-1.39%
1 Year Est. Return
+79.73%
3 Year Est. Return
+576.62%
5 Year Est. Return
+422.76%
10 Year Est. Return
+2,506.65%
AUM
$402M
AUM Growth
-$90.4M
Cap. Flow
-$75.3M
Cap. Flow %
-18.72%
Top 10 Hldgs %
43.57%
Holding
105
New
16
Increased
19
Reduced
23
Closed
32

Top Buys

Rank Stock Value
1
AVAH icon
Aveanna Healthcare
AVAH
+$14.3M
2
AMGN icon
Amgen
AMGN
+$8.61M
3
ITGR icon
Integer Holdings
ITGR
+$6.16M
4
HQY icon
HealthEquity
HQY
+$4.95M
5
SYRS
Syros Pharmaceuticals, Inc. Common Stock
SYRS
+$4.74M

Top Sells

Rank Stock Value
1
CAH icon
Cardinal Health
CAH
+$14.1M
2
CRIS icon
Curis
CRIS
+$11.5M
3
MRK icon
Merck
MRK
+$9.64M
4
ICLR icon
Icon
ICLR
+$9.33M
5
GSK icon
GSK
GSK
+$9.19M

Sector Composition

Rank Sector Weight
1 Healthcare 79.43%
2 Consumer Staples 2.03%
3 Technology 0.88%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
CBAY
51
DELISTED
Cymabay Therapeutics
CBAY
$2.45M 0.61%
562,339
– –
TVTX icon
52
Travere Therapeutics
TVTX
$5.2B
$2.19M 0.54%
+150,000
New +$2.96M
FUSN
53
DELISTED
Fusion Pharmaceuticals Inc. Common Shares
FUSN
$2.15M 0.53%
266,107
+16,688
+7% +$144K
MRSN
54
DELISTED
Mersana Therapeutics
MRSN
$2.14M 0.53%
6,290
– –
GOSS icon
55
Gossamer Bio
GOSS
$82.9M
$2.12M 0.53%
261,400
– –
RCOR
56
DELISTED
Renovacor, Inc.
RCOR
$1.99M 0.5%
200,000
-400,000
-67% -$4.03M
CAH icon
57
Cardinal Health
CAH
$53.9B
$1.93M 0.48%
33,818
-241,099
-88% -$14.1M
VINC
58
DELISTED
Vincerx Pharma, Inc. Common Stock
VINC
$1.83M 0.45%
7,046
+1,796
+34% +$547K
SRRA
59
DELISTED
Sierra Oncology, Inc. Common Stock
SRRA
$1.82M 0.45%
93,252
+12,300
+15% +$224K
ARNA
60
DELISTED
Arena Pharmaceuticals Inc
ARNA
$1.48M 0.37%
21,738
– –
DCOY
61
Decoy Therapeutics
DCOY
$2.19M
$1.44M 0.36%
38
-49
-56% -$2.18M
LITS
62
Lite Strategy Inc
LITS
$32.8M
$1.21M 0.3%
21,302
– –
AHACU
63
DELISTED
Alpha Healthcare Acquisition Corp Unit
AHACU
$1.14M 0.28%
100,000
– –
IDYA icon
64
IDEAYA Biosciences
IDYA
$3.42B
$1.01M 0.25%
48,298
– –
BCEL
65
DELISTED
Atreca, Inc. Class A Common Stock
BCEL
$967K 0.24%
113,455
– –
FULC icon
66
Fulcrum Therapeutics
FULC
$273M
$812K 0.2%
77,477
-113,795
-59% -$1.15M
LOGC
67
DELISTED
LogicBio Therapeutics, Inc. Common Stock
LOGC
$811K 0.2%
+182,630
New +$929K
SEER icon
68
Seer Inc
SEER
$122M
$779K 0.19%
+23,775
New +$938K
CMAX
69
DELISTED
CareMax, Inc. Class A Common Stock
CMAX
$459K 0.11%
+1,452
New +$576K
CVRX icon
70
CVRx
CVRX
$137M
$420K 0.1%
+15,000
New +$420K
MESO
71
PUT
Mesoblast
MESO
$1.84B
$410K 0.1%
27,400
-900
-3% -$14.1K
NGNE icon
72
Neurogene
NGNE
$656M
$354K 0.09%
1,916
– –
RUBY
73
DELISTED
Rubius Therapeutics, Inc
RUBY
$151K 0.04%
6,200
-53,600
-90% -$1.34M
ANIK icon
74
Anika Therapeutics
ANIK
$258M
– –
-40,000
Closed -$1.63M
AVTX icon
75
Avalo Therapeutics
AVTX
$965M
– –
-192
Closed -$1.67M
1 2
3
4 5

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Sio Capital Management's Q2 2021 Portfolio in Review

As of Q2 2021, Sio Capital Management held 105 positions worth $402M, down 18% from $493M the previous quarter. Its ten largest holdings account for 44% of the portfolio.

Sio Capital Management withdrew a net $75.3M in Q2 2021, closing 32 positions and reducing 23 holdings. Its most notable exit was Merck, an estimated $9.64M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 79% of assets, down from 87% a quarter earlier, followed by Consumer Staples and Technology.

Against the trend, Sio Capital Management opened a new position in Aveanna Healthcare worth $14.9M.

  • Sio Capital Management's largest Q2 2021 buy was Aveanna Healthcare: 1,201,607 shares worth $14.9M.
  • Sio Capital Management added most to NeuBase Therapeutics, Inc. Common Stock in Q2 2021, an estimated $2.62M increase.
  • Sio Capital Management's biggest Q2 2021 reduction was Cardinal Health, cutting an estimated $14.1M.
  • Sio Capital Management fully exited Merck in Q2 2021, selling an estimated $9.64M.
  • Sio Capital Management's ten largest holdings make up 44% of its $402M portfolio in Q2 2021.
  • Sio Capital Management opened 16 new positions and closed 32 in Q2 2021.
  • Sio Capital Management's portfolio value fell 18% quarter-over-quarter to $402M.

Based on Sio Capital Management's 13F filing for Q2 2021, filed 16 Aug 2021.