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Sio Capital Management Portfolio holdings

AUM $697M
1-Year Est. Return 79.73%
This Fund
S&P 500
This Quarter Est. Return
-13.49%
1 Year Est. Return
+79.73%
3 Year Est. Return
+576.62%
5 Year Est. Return
+422.76%
10 Year Est. Return
+2,506.65%
AUM
$298M
AUM Growth
-$121M
Cap. Flow
-$79.8M
Cap. Flow %
-26.73%
Top 10 Hldgs %
49.77%
Holding
104
New
36
Increased
13
Reduced
16
Closed
35

Top Buys

Rank Stock Value
1
AMGN icon
Amgen
AMGN
+$23.2M
2
NVST icon
Envista
NVST
+$21.9M
3
BSX icon
Boston Scientific
BSX
+$15.5M
4
BIIB icon
Biogen
BIIB
+$12.7M
5
GLD icon
SPDR Gold Trust
GLD
+$9.63M

Top Sells

Rank Stock Value
1
MDT icon
Medtronic
MDT
+$16.7M
2
PFE icon
Pfizer
PFE
+$14.9M
3
WCG
Wellcare Health Plans, Inc.
WCG
+$14.8M
4
GILD icon
Gilead Sciences
GILD
+$12.1M
5
GSK icon
GSK
GSK
+$9.62M

Sector Composition

Rank Sector Weight
1 Healthcare 83.72%
2 Financials 0.58%
3 Technology 0.32%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
GYRE icon
51
Gyre Therapeutics
GYRE
$715M
$956K 0.32%
29,162
+1,872
+7% +$86K
NXGN
52
DELISTED
NextGen Healthcare, Inc. Common Stock
NXGN
$946K 0.32%
+90,657
New +$1.17M
DYAI icon
53
Dyadic International
DYAI
$36.8M
$935K 0.31%
+179,795
New +$949K
PGNY icon
54
Progyny
PGNY
$2.26B
$913K 0.31%
43,100
-1,810
-4% -$49.7K
BCEL
55
DELISTED
Atreca, Inc. Class A Common Stock
BCEL
$782K 0.26%
47,252
-38,060
-45% -$690K
MORF
56
DELISTED
Morphic Holding, Inc. Common Stock
MORF
$729K 0.24%
+49,686
New +$833K
KOD icon
57
Kodiak Sciences
KOD
$2.86B
$716K 0.24%
+15,000
New +$900K
IMVTW
58
DELISTED
Immunovant, Inc. Warrants expiring 12/18/2024
IMVTW
$715K 0.24%
+307,700
New +$591K
SUPN icon
59
Supernus Pharmaceuticals
SUPN
$2.72B
$450K 0.15%
+25,000
New +$525K
ARAV
60
DELISTED
Aravive, Inc. Common Stock
ARAV
$441K 0.15%
76,514
-21,687
-22% -$194K
PRVB
61
DELISTED
Provention Bio, Inc. Common Stock
PRVB
$387K 0.13%
+42,100
New +$543K
RAPT
62
DELISTED
RAPT Therapeutics
RAPT
$304K 0.1%
+1,787
New +$407K
AMRN
63
Amarin Corp
AMRN
$303M
$200K 0.07%
+2,500
New +$831K
CBAY
64
DELISTED
Cymabay Therapeutics
CBAY
$196K 0.07%
+132,474
New +$222K
SRRA
65
DELISTED
Sierra Oncology, Inc. Common Stock
SRRA
$151K 0.05%
+15,395
New +$202K
MIRM icon
66
Mirum Pharmaceuticals
MIRM
$6.04B
$150K 0.05%
+10,701
New +$176K
YARW
67
Yarrow Bioscience, Inc. Common Stock
YARW
$115M
$61K 0.02%
+6
New +$94.1K
BLCM
68
DELISTED
Bellicum Pharmaceuticals, Inc.
BLCM
$58K 0.02%
+12,272
New +$132K
MESO
69
PUT
Mesoblast
MESO
$2.05B
$35K 0.01%
+4,050
New +$62.1K
ABEO icon
70
Abeona Therapeutics
ABEO
$409M
– –
-11,301
Closed -$924K
ALNY icon
71
Alnylam Pharmaceuticals
ALNY
$28.7B
– –
-36,632
Closed -$4.22M
ARVN icon
72
Arvinas
ARVN
$570M
– –
-30,052
Closed -$1.24M
BNGO icon
73
Bionano Genomics
BNGO
$12.9M
– –
-2,018
Closed -$1.5M
DTIL icon
74
Precision BioSciences
DTIL
$204M
– –
-1,448
Closed -$603K
GILD icon
75
Gilead Sciences
GILD
$165B
– –
-186,000
Closed -$12.1M
1 2
3
4 5

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Sio Capital Management's Q1 2020 Portfolio in Review

As of Q1 2020, Sio Capital Management held 104 positions worth $298M, down 29% from $420M the previous quarter. Its ten largest holdings account for 50% of the portfolio.

Sio Capital Management withdrew a net $79.8M in Q1 2020, closing 35 positions and reducing 16 holdings. Its most notable exit was Medtronic, an estimated $16.7M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 84% of assets, up from 72% a quarter earlier, followed by Financials and Technology.

Against the trend, Sio Capital Management opened a new position in Amgen worth $21.5M.

  • Sio Capital Management's largest Q1 2020 buy was Amgen: 106,069 shares worth $21.5M.
  • Sio Capital Management added most to McKesson in Q1 2020, an estimated $9.36M increase.
  • Sio Capital Management's biggest Q1 2020 reduction was Trillium Therapeutics Inc., cutting an estimated $8.82M.
  • Sio Capital Management fully exited Medtronic in Q1 2020, selling an estimated $16.7M.
  • Sio Capital Management's ten largest holdings make up 50% of its $298M portfolio in Q1 2020.
  • Sio Capital Management opened 36 new positions and closed 35 in Q1 2020.
  • Sio Capital Management's portfolio value fell 29% quarter-over-quarter to $298M.

Based on Sio Capital Management's 13F filing for Q1 2020, filed 15 May 2020.