SCM

Sio Capital Management Portfolio holdings

AUM $249M

2025 Q2 2025 Q1 2024 Q4 2024 Q3 2024 Q2 2024 Q1 2023 Q4 2023 Q3 2023 Q2 2023 Q1 2022 Q4 2022 Q3 2022 Q2 2022 Q1 2021 Q4 2021 Q3 2021 Q2 2021 Q1 2020 Q4 2020 Q3 2020 Q2 2020 Q1 2019 Q4 2019 Q3 2019 Q2 2019 Q1 2018 Q4 2018 Q3 2018 Q2 2018 Q1 2017 Q4 2017 Q3 2017 Q2 2017 Q1 2016 Q4 2016 Q3 2016 Q2 2016 Q1 2015 Q4 2015 Q3 2015 Q2 2015 Q1 2014 Q4

This Quarter Return

+9.52%

1 Year Return

+117.71%

3 Year Return

+238.99%

5 Year Return

+411.91%

10 Year Return

+912.87%

AUM

$106M

AUM Growth

+$106M (-15%)

Cap. Flow

-$25.8M

Cap. Flow % of AUM

-24.32%

Top 10 Holdings % Top 10 Hldgs %

63.48%

Holding

New

Increased

Reduced

Closed

Top Buys

1	Elevance Health ELV	$6.98M
2	GSK GSK	$5.47M
3	Viking Therapeutics VKTX	$5.08M
4	WCG Wellcare Health Plans, Inc. WCG	$4.67M
5	Eli Lilly LLY	$4.55M

Top Sells

1	DMK DMK Pharmaceuticals Corporation Common Stock DMK	$10.1M
2	SIOX Sio Gene Therapies Inc. Common Stock SIOX	$7.7M
3	Biogen BIIB	$4.87M
4	QTNT Quotient Limited Ordinary Shares QTNT	$4.54M
5	Globus Medical GMED	$4.38M

Sector Composition

1	Healthcare	82.39%
2	Financials	9.88%
3	Technology	1.58%
4	Industrials	0%

Communication Services

Advertising Agencies

Broadcasting

Electronic Gaming & Multimedia

Entertainment

Internet Content & Information

Publishing

Telecom Services

Consumer Discretionary

Apparel Manufacturing

Apparel Retail

Auto Manufacturers

Auto Parts

Auto & Truck Dealerships

Department Stores

Footwear & Accessories

Furnishings, Fixtures & Appliances

Gambling

Home Improvement Retail

Internet Retail

Leisure

Lodging

Luxury Goods

Packaging & Containers

Personal Services

Recreational Vehicles

Residential Construction

Resorts & Casinos

Restaurants

Specialty Retail

Textile Manufacturing

Travel Services

Consumer Staples

Beverages - Brewers

Beverages - Non-Alcoholic

Beverages - Wineries & Distilleries

Confectioners

Discount Stores

Education & Training Services

Farm Products

Food Distribution

Grocery Stores

Household & Personal Products

Packaged Foods

Tobacco

Energy

Oil & Gas Drilling

Oil & Gas Equipment & Services

Oil & Gas Exploration & Production

Oil & Gas Integrated

Oil & Gas Midstream

Oil & Gas Refining & Marketing

Thermal Coal

Uranium

Financials

Asset Management

Banks - Diversified

Banks - Regional

Capital Markets

Credit Services

Diversified Insurance

Financial Conglomerates

Financial Data & Stock Exchanges

Insurance Brokers

Life Insurance

Mortgage Finance

Property & Casualty Insurance

Reinsurance

Shell Companies

Specialty - Insurance

Healthcare

Biotechnology

Diagnostics & Research

Drug Manufacturers - General

Drug Manufacturers - Specialty & Generic

Healthcare Plans

Health Information Services

Medical Care Facilities

Medical Devices

Medical Distribution

Medical Instruments & Supplies

Pharmaceutical Retailers

Industrials

Aerospace & Defense

Airlines

Airports & Air Services

Building Products & Equipment

Business Equipment & Supplies

Conglomerates

Consulting Services

Electrical Equipment & Parts

Engineering & Construction

Farm & Heavy Construction Machinery

Industrial Distribution

Infrastructure Operations

Integrated Freight & Logistics

Marine Shipping

Metal Fabrication

Pollution & Treatment Controls

Railroads

Rental & Leasing Services

Security & Protection Services

Specialty Business Services

Specialty Industrial Machinery

Staffing & Employment Services

Tools & Accessories

Trucking

Waste Management

Materials

Agricultural Inputs

Aluminum

Building Materials

Chemicals

Coking Coal

Copper

Gold

Lumber & Wood Production

Other Industrial Metals & Mining

Other Precious Metals & Mining

Paper & Paper Products

Silver

Specialty Chemicals

Steel

Real Estate

Diversified REIT

Healthcare Facilities REIT

Hotel & Motel REIT

Industrial REIT

Mortgage REIT

Office REIT

Real Estate Development

Real Estate Diversified

Real Estate Services

Residential REIT

Retail REIT

Specialty REIT

Technology

Communication Equipment

Computer Hardware

Consumer Electronics

Electronic Components

Electronics & Computer Distribution

Information Technology Services

Scientific & Technical Instruments

Semiconductor Equipment & Materials

Semiconductors

Software - Application

Software - Infrastructure

Solar

Utilities

Diversified Utilities

Electric Utilities

Gas Utilities

Independent Power Producers

Renewable Electricity

Water Utilities

#	Name	Market Value	Portfolio Weight	Shares or Principal	Shares Change %	Capital Flow
51	51 Medtronic MDT $118B	–	–	-55,844	Closed	-$4.34M
52	52 Pfizer PFE $141B	–	–	0	–	–
53	53 Premier PINC $2.11B	–	–	0	–	–
54	SAGE 54 DELISTED Sage Therapeutics SAGE	–	–	0	–	–
55	55 Sanofi SNY $122B	–	–	-45,099	Closed	-$2.25M
56	56 Spyre Therapeutics SYRE $1.02B	–	–	-5,183	Closed	-$639K
57	57 TriNet TNET $3.46B	–	–	0	–	–
58	58 Zimmer Biomet ZBH $20.8B	–	–	-31,964	Closed	-$3.63M
59	59 Zoetis ZTS $67.6B	–	–	0	–	–
60	VIRX 60 DELISTED Viracta Therapeutics, Inc. Common Stock VIRX	–	–	-963	Closed	-$65K
61	EGRX 61 DELISTED Eagle Pharmaceuticals, Inc. EGRX	–	–	-63,835	Closed	-$3.81M
62	CBAY 62 DELISTED Cymabay Therapeutics CBAY	–	–	-75,000	Closed	-$605K
63	DMK 63 DELISTED DMK Pharmaceuticals Corporation Common Stock DMK	–	–	-27,657	Closed	-$10.1M
64	SGEN 64 DELISTED Seagen Inc. Common Stock SGEN	–	–	0	–	–
65	NXGN 65 DELISTED NextGen Healthcare, Inc. Common Stock NXGN	–	–	0	–	–
66	SIOX 66 DELISTED Sio Gene Therapies Inc. Common Stock SIOX	–	–	-139,862	Closed	-$7.7M
67	OTIC 67 DELISTED Otonomy, Inc. OTIC	–	–	-100,900	Closed	-$328K
68	NTUS 68 DELISTED Natus Medical Inc NTUS	–	–	0	–	–
69	ARNA 69 DELISTED Arena Pharmaceuticals Inc ARNA	–	–	-72,086	Closed	-$1.84M
70	LMNX 70 DELISTED Luminex Corp LMNX	–	–	-115,979	Closed	-$2.36M
71	PFNX 71 DELISTED Pfenex Inc. PFNX	–	–	-85,867	Closed	-$259K