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Sio Capital Management Portfolio holdings

AUM $697M
1-Year Est. Return 79.73%
This Fund
S&P 500
This Quarter Est. Return
-3.76%
1 Year Est. Return
+79.73%
3 Year Est. Return
+576.62%
5 Year Est. Return
+422.76%
10 Year Est. Return
+2,506.65%
AUM
$302M
AUM Growth
-$29.4M
Cap. Flow
-$9.85M
Cap. Flow %
-3.26%
Top 10 Hldgs %
56.17%
Holding
86
New
16
Increased
11
Reduced
16
Closed
20

Top Buys

Rank Stock Value
1
LH icon
Labcorp
LH
+$13.5M
2
SNY icon
Sanofi
SNY
+$10.9M
3
INGN icon
Inogen
INGN
+$9.8M
4
VREX icon
Varex Imaging
VREX
+$8.02M
5
MEDP icon
Medpace
MEDP
+$4.68M

Top Sells

Rank Stock Value
1
CAH icon
Cardinal Health
CAH
+$17.3M
2
GLD icon
SPDR Gold Trust
GLD
+$15.4M
3
CI icon
Cigna
CI
+$12.5M
4
HLF icon
Herbalife
HLF
+$9.88M
5
LKFT
Lakefront Biotherapeutics American Depositary Shares
LKFT
+$7.02M

Sector Composition

Rank Sector Weight
1 Healthcare 73.08%
2 Financials 7.52%
3 Industrials 0.43%
4 Consumer Staples 0%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
PNT
26
DELISTED
POINT Biopharma Global Inc. Common Stock
PNT
$3.01M 1%
377,684
– –
VKTX icon
27
Viking Therapeutics
VKTX
$3.95B
$3M 0.99%
999,829
+339,016
+51% +$1.22M
AFMD
28
DELISTED
Affimed
AFMD
$2.81M 0.93%
+64,366
New +$2.8M
INBX
29
DELISTED
Inhibrx, Inc. Common Stock
INBX
$2.77M 0.92%
+124,250
New +$3.17M
OBIO icon
30
Orchestra BioMed
OBIO
$247M
$2.48M 0.82%
250,000
– –
EUCRU
31
DELISTED
Eucrates Biomedical Acquisition Corp. Unit
EUCRU
$2.45M 0.81%
248,674
– –
MRUS
32
DELISTED
Merus
MRUS
$2.38M 0.79%
90,000
– –
BCYC
33
Bicycle Therapeutics
BCYC
$278M
$2.32M 0.77%
52,788
-1,212
-2% -$56.6K
PRDS
34
DELISTED
Pardes Biosciences, Inc. Common Stock
PRDS
$2.28M 0.75%
315,564
+3,126
+1% +$30.7K
FUSN
35
DELISTED
Fusion Pharmaceuticals Inc. Common Shares
FUSN
$2.02M 0.67%
259,763
– –
SYRE icon
36
Spyre Therapeutics
SYRE
$9.18B
$2M 0.66%
34,844
+14,904
+75% +$1.25M
MBRX icon
37
Moleculin Biotech
MBRX
$2.78M
$1.85M 0.61%
2,775
– –
VNDA icon
38
Vanda Pharmaceuticals
VNDA
$302M
$1.84M 0.61%
+162,478
New +$2.14M
CNTB
39
Connect Biopharma Holdings
CNTB
$139M
$1.8M 0.6%
+597,678
New +$2.52M
CBAY
40
DELISTED
Cymabay Therapeutics
CBAY
$1.75M 0.58%
562,339
– –
NBSE
41
DELISTED
NeuBase Therapeutics, Inc. Common Stock
NBSE
$1.7M 0.56%
45,322
– –
SRRA
42
DELISTED
Sierra Oncology, Inc. Common Stock
SRRA
$1.56M 0.52%
48,768
-46,682
-49% -$1.34M
ISO
43
DELISTED
IsoPlexis Corporation Common Stock
ISO
$1.4M 0.46%
407,102
-87,910
-18% -$509K
BGMS
44
Bio Green Med Solution Inc
BGMS
$5.35M
$1.29M 0.43%
117
– –
TYRA icon
45
Tyra Biosciences
TYRA
$1.62B
$1.19M 0.39%
+111,033
New +$1.32M
ASLN
46
DELISTED
ASLAN Pharmaceuticals Limited American Depositary Shares
ASLN
$1.14M 0.38%
31,769
– –
ANIP icon
47
ANI Pharmaceuticals
ANIP
$1.85B
$1.12M 0.37%
40,000
– –
SYRS
48
DELISTED
Syros Pharmaceuticals, Inc. Common Stock
SYRS
$1.07M 0.36%
90,291
+223
+0.2% +$3.99K
SVRA icon
49
Savara
SVRA
$1.17B
$938K 0.31%
716,262
+65,092
+10% +$78.4K
ELEV
50
DELISTED
Elevation Oncology
ELEV
$907K 0.3%
359,731
+109,731
+44% +$440K
1
2
3 4

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Sio Capital Management's Q1 2022 Portfolio in Review

As of Q1 2022, Sio Capital Management held 86 positions worth $302M, down 8.9% from $332M the previous quarter. Its ten largest holdings account for 56% of the portfolio.

Sio Capital Management withdrew a net $9.85M in Q1 2022, closing 20 positions and reducing 16 holdings. Its most notable exit was Cardinal Health, an estimated $17.3M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 73% of assets, down from 83% a quarter earlier, followed by Financials and Industrials.

Against the trend, Sio Capital Management opened a new position in Labcorp worth $13M.

  • Sio Capital Management's largest Q1 2022 buy was Labcorp: 57,418 shares worth $13M.
  • Sio Capital Management added most to Sanofi in Q1 2022, an estimated $10.9M increase.
  • Sio Capital Management's biggest Q1 2022 reduction was Cigna, cutting an estimated $12.5M.
  • Sio Capital Management fully exited Cardinal Health in Q1 2022, selling an estimated $17.3M.
  • Sio Capital Management's ten largest holdings make up 56% of its $302M portfolio in Q1 2022.
  • Sio Capital Management opened 16 new positions and closed 20 in Q1 2022.
  • Sio Capital Management's portfolio value fell 8.9% quarter-over-quarter to $302M.

Based on Sio Capital Management's 13F filing for Q1 2022, filed 16 May 2022.