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Sio Capital Management Portfolio holdings

AUM $697M
1-Year Est. Return 79.73%
This Fund
S&P 500
This Quarter Est. Return
-13.49%
1 Year Est. Return
+79.73%
3 Year Est. Return
+576.62%
5 Year Est. Return
+422.76%
10 Year Est. Return
+2,506.65%
AUM
$298M
AUM Growth
-$121M
Cap. Flow
-$79.8M
Cap. Flow %
-26.73%
Top 10 Hldgs %
49.77%
Holding
104
New
36
Increased
13
Reduced
16
Closed
35

Top Buys

Rank Stock Value
1
AMGN icon
Amgen
AMGN
+$23.2M
2
NVST icon
Envista
NVST
+$21.9M
3
BSX icon
Boston Scientific
BSX
+$15.5M
4
BIIB icon
Biogen
BIIB
+$12.7M
5
GLD icon
SPDR Gold Trust
GLD
+$9.63M

Top Sells

Rank Stock Value
1
MDT icon
Medtronic
MDT
+$16.7M
2
PFE icon
Pfizer
PFE
+$14.9M
3
WCG
Wellcare Health Plans, Inc.
WCG
+$14.8M
4
GILD icon
Gilead Sciences
GILD
+$12.1M
5
GSK icon
GSK
GSK
+$9.62M

Sector Composition

Rank Sector Weight
1 Healthcare 83.72%
2 Financials 0.58%
3 Technology 0.32%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
ARDX icon
26
Ardelyx
ARDX
$1.2B
$3.53M 1.18%
621,534
– –
VKTX icon
27
Viking Therapeutics
VKTX
$3.88B
$3.52M 1.18%
752,241
+20,788
+3% +$128K
WBA
28
CALL
DELISTED
Walgreens Boots Alliance
WBA
$3.17M 1.06%
+69,400
New +$3.52M
SYNH
29
DELISTED
Syneos Health, Inc. Class A Common Stock
SYNH
$3.04M 1.02%
77,131
+23,834
+45% +$1.39M
SYRS
30
DELISTED
Syros Pharmaceuticals, Inc. Common Stock
SYRS
$2.78M 0.93%
46,853
+2,000
+4% +$136K
ESPR
31
DELISTED
Esperion Therapeutics
ESPR
$2.54M 0.85%
80,600
+23,942
+42% +$1.26M
ALKS icon
32
Alkermes
ALKS
$8.11B
$2.45M 0.82%
+170,042
New +$3.04M
LSACU
33
DELISTED
LifeSci Acquisition Corp. Unit 1 COM & 1 WT
LSACU
$2.1M 0.7%
+210,000
New +$2.08M
MD icon
34
Pediatrix Medical
MD
$2.15B
$2.06M 0.69%
+176,690
New +$3.64M
RVLP
35
DELISTED
RVL Pharmaceuticals plc Ordinary Shares
RVLP
$1.83M 0.61%
+575,000
New +$3.06M
LRMR icon
36
Larimar Therapeutics
LRMR
$436M
$1.8M 0.6%
194,347
+4,083
+2% +$53.7K
IMVT icon
37
Immunovant
IMVT
$8.2B
$1.78M 0.6%
114,133
-501,267
-81% -$7.54M
CYPH
38
Cypherpunk Technologies Inc
CYPH
$71.7M
$1.74M 0.58%
109,954
+62,332
+131% +$1.21M
TRIL
39
DELISTED
Trillium Therapeutics Inc.
TRIL
$1.69M 0.57%
417,577
-2,333,609
-85% -$8.82M
AFMD
40
DELISTED
Affimed
AFMD
$1.61M 0.54%
101,820
– –
ASND icon
41
Ascendis Pharma A/S
ASND
$16.4B
$1.56M 0.52%
+13,889
New +$1.8M
HQY icon
42
HealthEquity
HQY
$8.65B
$1.55M 0.52%
+30,700
New +$2.04M
MEDP icon
43
Medpace
MEDP
$16.3B
$1.53M 0.51%
20,858
-5,743
-22% -$499K
KDMN
44
DELISTED
Kadmon Holdings, Inc.
KDMN
$1.41M 0.47%
+337,500
New +$1.45M
COR icon
45
Cencora
COR
$63.2B
$1.41M 0.47%
15,928
-95,321
-86% -$8.4M
ASLN
46
DELISTED
ASLAN Pharmaceuticals Limited American Depositary Shares
ASLN
$1.32M 0.44%
32,373
+6,924
+27% +$526K
VSTM icon
47
Verastem
VSTM
$519M
$1.3M 0.44%
+41,007
New +$1.03M
HROW icon
48
Harrow
HROW
$1.49B
$1.19M 0.4%
311,640
-33,300
-10% -$197K
NGNE icon
49
Neurogene
NGNE
$710M
$1M 0.34%
4,409
– –
MRSN
50
DELISTED
Mersana Therapeutics
MRSN
$969K 0.32%
6,650
– –
1
2
3 4 5

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Sio Capital Management's Q1 2020 Portfolio in Review

As of Q1 2020, Sio Capital Management held 104 positions worth $298M, down 29% from $420M the previous quarter. Its ten largest holdings account for 50% of the portfolio.

Sio Capital Management withdrew a net $79.8M in Q1 2020, closing 35 positions and reducing 16 holdings. Its most notable exit was Medtronic, an estimated $16.7M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 84% of assets, up from 72% a quarter earlier, followed by Financials and Technology.

Against the trend, Sio Capital Management opened a new position in Amgen worth $21.5M.

  • Sio Capital Management's largest Q1 2020 buy was Amgen: 106,069 shares worth $21.5M.
  • Sio Capital Management added most to McKesson in Q1 2020, an estimated $9.36M increase.
  • Sio Capital Management's biggest Q1 2020 reduction was Trillium Therapeutics Inc., cutting an estimated $8.82M.
  • Sio Capital Management fully exited Medtronic in Q1 2020, selling an estimated $16.7M.
  • Sio Capital Management's ten largest holdings make up 50% of its $298M portfolio in Q1 2020.
  • Sio Capital Management opened 36 new positions and closed 35 in Q1 2020.
  • Sio Capital Management's portfolio value fell 29% quarter-over-quarter to $298M.

Based on Sio Capital Management's 13F filing for Q1 2020, filed 15 May 2020.