Simplex Trading
PRME icon

Simplex Trading’s Prime Medicine PRME Stock Holding History

Simplex Trading’s Portfolio PRME Stock Details PRME Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$265K Sell
76,200
-68,700
-47% -$261K ﹤0.01% 3956
2025
Q4 		$503K Buy
144,900
+27,800
+24% +$124K ﹤0.01% 3296
2025
Q3 		$648K Sell
117,100
-71,100
-38% -$289K ﹤0.01% 3520
2025
Q2 		$464K Buy
188,200
+175,900
+1,430% +$271K ﹤0.01% 3582
2025
Q1 		$24K Sell
12,300
-3,800
-24% -$9.69K ﹤0.01% 6435
2024
Q4 		$47K Buy
+16,100
New +$56.5K ﹤0.01% 5939
2024
Q3 		– Sell
-2,300
Closed -$11K – 9333
2024
Q2 		$11K Sell
2,300
-1,200
-34% -$7.28K ﹤0.01% 7379
2024
Q1 		$24K Buy
3,500
+2,200
+169% +$16.7K ﹤0.01% 6957
2023
Q4 		$11K Buy
+1,300
New +$10K ﹤0.01% 7375

Other funds holding PRME

AI
Alphabet Inc Mountain View, California $4.02B AUM 215.74% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
AIM
ARK Investment Management St. Petersburg, Florida $12.9B AUM 64.92% 1-Year Est. Return
T. Rowe Price Investment Management
T. Rowe Price Investment Management Baltimore, Maryland $145B AUM 22.78% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
Balyasny Asset Management
Balyasny Asset Management Chicago, Illinois $77.1B AUM 42.89% 1-Year Est. Return
CC
Casdin Capital New York $1.32B AUM 76.62% 1-Year Est. Return
WP
Woodline Partners San Francisco, California $26.4B AUM 44.85% 1-Year Est. Return
Sumitomo Mitsui Trust Group
Sumitomo Mitsui Trust Group Minato-Ku, Tokyo, Japan $154B AUM 29.96% 1-Year Est. Return

Simplex Trading's PRME Position: Q4 2025 in Review

Simplex Trading sold out of Prime Medicine (PRME) in Q4 2025, closing a stake of 157,897 shares — an estimated $702K sold.

Simplex Trading first reported a position in PRME in Q1 2024 and held it in 5 quarters. The position peaked at $874K in Q3 2025. 183 funds tracked by Wall St. Rank hold PRME as of Q4 2025.

  • Simplex Trading reported no remaining Prime Medicine position as of Q4 2025 after selling out during the quarter.
  • Simplex Trading sold 157,897 Prime Medicine shares in Q4 2025, an estimated $702K.
  • Simplex Trading first reported a position in Prime Medicine in Q1 2024 and held it in 5 quarters.
  • Simplex Trading's Prime Medicine position peaked at $874K in Q3 2025.
  • 183 funds tracked by Wall St. Rank held Prime Medicine as of Q4 2025.

Based on Simplex Trading's 13F filing for Q4 2025, filed 11 Feb 2026.