Simplex Trading
MREO

Simplex Trading’s Mereo BioPharma MREO Stock Holding History

Simplex Trading’s Portfolio MREO Stock Details MREO Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$31 Sell
100
-53,300
-100% -$16K ﹤0.01% 9137
2026
Q1 		$17.6K Sell
53,400
-533,000
-91% -$229K ﹤0.01% 6875
2025
Q4 		$245K Buy
586,400
+577,000
+6,138% +$1.1M ﹤0.01% 4021
2025
Q3 		$19K Sell
9,400
-15,600
-62% -$28.8K ﹤0.01% 7369
2025
Q2 		$67K Buy
25,000
+1,800
+8% +$4.34K ﹤0.01% 5627
2025
Q1 		$52K Sell
23,200
-9,800
-30% -$27.7K ﹤0.01% 5731
2024
Q4 		$115K Sell
33,000
-700
-2% -$2.75K ﹤0.01% 5057
2024
Q3 		$138K Buy
33,700
+7,400
+28% +$30.6K ﹤0.01% 4900
2024
Q2 		$94K Sell
26,300
-3,700
-12% -$12K ﹤0.01% 5440
2024
Q1 		$99K Buy
30,000
+26,900
+868% +$91.1K ﹤0.01% 5588
2023
Q4 		$7K Buy
3,100
+2,100
+210% +$4.02K ﹤0.01% 7678
2023
Q3 		$1K Hold
1,000
– – ﹤0.01% 8362
2023
Q2 		$1K Buy
+1,000
New +$1.16K ﹤0.01% 8659
2022
Q3 		– Sell
-900
Closed -$1K – 10523
2022
Q2 		$1K Sell
900
-600
-40% -$465 ﹤0.01% 9620
2022
Q1 		$1K Sell
1,500
-500
-25% -$647 ﹤0.01% 10106
2021
Q4 		$3K Sell
2,000
-36,600
-95% -$73.2K ﹤0.01% 9843
2021
Q3 		$121K Hold
38,600
– – ﹤0.01% 6350
2021
Q2 		$122K Buy
38,600
+38,045
+6,855% +$128K ﹤0.01% 6444
2021
Q1 		$187K Buy
+555
New +$1.96K ﹤0.01% 4841

Other funds holding MREO

RCMNY
Rubric Capital Management (New York) New York $10.9B AUM 70.31% 1-Year Est. Return
6CM
683 Capital Management New York $2.04B AUM 94.26% 1-Year Est. Return
Bank of America
Bank of America Charlotte, North Carolina $1.55T AUM 33.47% 1-Year Est. Return
DCM
Defilade Capital Management Emeryville, California $747M AUM
NM
Newtyn Management New York $801M AUM 23.14% 1-Year Est. Return
TC
Tejara Capital London, United Kingdom $243M AUM 9.84% 1-Year Est. Return
UBS Group
UBS Group Zurich, Switzerland $786B AUM 40.34% 1-Year Est. Return
Two Sigma Investments
Two Sigma Investments New York $138B AUM 41.87% 1-Year Est. Return
EC
EcoR1 Capital San Francisco, California $2.06B AUM 215.32% 1-Year Est. Return
Jane Street
Jane Street New York $1.21T AUM 78.12% 1-Year Est. Return

Simplex Trading's MREO Position: Q2 2026 in Review

Simplex Trading opened a new position in Mereo BioPharma (MREO) in Q2 2026: 18,780 shares worth $5.97K. The stake represents ﹤0.01% of the portfolio and ranks #8066 among its holdings. This is a return to the name: Simplex Trading previously reported a position in MREO as recently as Q4 2025.

Simplex Trading first reported a position in MREO in Q1 2021 and has held it in 17 quarters since. The position peaked at $545K in Q2 2025. 61 funds tracked by Wall St. Rank hold MREO as of Q2 2026.

  • Simplex Trading held 18,780 shares of Mereo BioPharma worth $5.97K as of Q2 2026.
  • Mereo BioPharma was a new Simplex Trading position in Q2 2026.
  • Mereo BioPharma made up ﹤0.01% of Simplex Trading's portfolio in Q2 2026, its #8066 holding.
  • Simplex Trading first reported a position in Mereo BioPharma in Q1 2021 and has held it in 17 quarters since.
  • Simplex Trading's Mereo BioPharma position peaked at $545K in Q2 2025.
  • 61 funds tracked by Wall St. Rank held Mereo BioPharma as of Q2 2026.

Based on Simplex Trading's 13F filing for Q2 2026, filed 12 Aug 2026.