Simplex Trading
MREO

Simplex Trading’s Mereo BioPharma MREO Stock Holding History

Simplex Trading’s Portfolio MREO Stock Details MREO Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$17.6K Sell
53,400
-533,000
-91% -$229K ﹤0.01% 6875
2025
Q4 		$245K Buy
586,400
+577,000
+6,138% +$1.1M ﹤0.01% 4021
2025
Q3 		$19K Sell
9,400
-15,600
-62% -$28.8K ﹤0.01% 7369
2025
Q2 		$67K Buy
25,000
+1,800
+8% +$4.34K ﹤0.01% 5627
2025
Q1 		$52K Sell
23,200
-9,800
-30% -$27.7K ﹤0.01% 5731
2024
Q4 		$115K Sell
33,000
-700
-2% -$2.75K ﹤0.01% 5057
2024
Q3 		$138K Buy
33,700
+7,400
+28% +$30.6K ﹤0.01% 4900
2024
Q2 		$94K Sell
26,300
-3,700
-12% -$12K ﹤0.01% 5440
2024
Q1 		$99K Buy
30,000
+26,900
+868% +$91.1K ﹤0.01% 5588
2023
Q4 		$7K Buy
3,100
+2,100
+210% +$4.02K ﹤0.01% 7678
2023
Q3 		$1K Hold
1,000
– – ﹤0.01% 8362
2023
Q2 		$1K Buy
+1,000
New +$1.16K ﹤0.01% 8659
2022
Q3 		– Sell
-900
Closed -$1K – 10523
2022
Q2 		$1K Sell
900
-600
-40% -$465 ﹤0.01% 9620
2022
Q1 		$1K Sell
1,500
-500
-25% -$647 ﹤0.01% 10106
2021
Q4 		$3K Sell
2,000
-36,600
-95% -$73.2K ﹤0.01% 9843
2021
Q3 		$121K Hold
38,600
– – ﹤0.01% 6350
2021
Q2 		$122K Buy
38,600
+38,045
+6,855% +$128K ﹤0.01% 6444
2021
Q1 		$187K Buy
+555
New +$1.96K ﹤0.01% 4841

Other funds holding MREO

RCMNY
Rubric Capital Management (New York) New York $9.44B AUM 68.42% 1-Year Est. Return
EC
EcoR1 Capital San Francisco, California $2.36B AUM 204.53% 1-Year Est. Return
6CM
683 Capital Management New York $1.92B AUM 85.52% 1-Year Est. Return
Bank of America
Bank of America Charlotte, North Carolina $1.37T AUM 24.88% 1-Year Est. Return
DCM
Defilade Capital Management Emeryville, California $712M AUM
NM
Newtyn Management New York $936M AUM 27.23% 1-Year Est. Return
Millennium Management
Millennium Management New York $240B AUM 35.51% 1-Year Est. Return
TC
Tejara Capital London, United Kingdom $303M AUM 5.43% 1-Year Est. Return
UBS Group
UBS Group Zurich, Switzerland $666B AUM 30.12% 1-Year Est. Return
WANY
Wealthspire Advisors (New York) New York $12.7B AUM 17.31% 1-Year Est. Return

Simplex Trading's MREO Position: Q1 2026 in Review

Simplex Trading sold out of Mereo BioPharma (MREO) in Q1 2026, closing a stake of 419,477 shares — an estimated $180K sold.

Simplex Trading first reported a position in MREO in Q1 2021 and held it in 16 quarters. The position peaked at $545K in Q2 2025. 63 funds tracked by Wall St. Rank hold MREO as of Q1 2026.

  • Simplex Trading reported no remaining Mereo BioPharma position as of Q1 2026 after selling out during the quarter.
  • Simplex Trading sold 419,477 Mereo BioPharma shares in Q1 2026, an estimated $180K.
  • Simplex Trading first reported a position in Mereo BioPharma in Q1 2021 and held it in 16 quarters.
  • Simplex Trading's Mereo BioPharma position peaked at $545K in Q2 2025.
  • 63 funds tracked by Wall St. Rank held Mereo BioPharma as of Q1 2026.

Based on Simplex Trading's 13F filing for Q1 2026, filed 14 May 2026.