Simplex Trading
MREO

Simplex Trading’s Mereo BioPharma MREO Stock Holding History

Simplex Trading’s Portfolio MREO Stock Details MREO Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		– Sell
-419,477
Closed -$180K – 9753
2025
Q4 		$175K Buy
419,477
+223,208
+114% +$425K ﹤0.01% 4361
2025
Q3 		$404K Sell
196,269
-4,872
-2% -$8.98K ﹤0.01% 4097
2025
Q2 		$545K Buy
201,141
+197,024
+4,786% +$475K ﹤0.01% 3416
2025
Q1 		$9K Sell
4,117
-50,982
-93% -$144K ﹤0.01% 7178
2024
Q4 		$192K Buy
55,099
+21,244
+63% +$83.5K ﹤0.01% 4558
2024
Q3 		$139K Sell
33,855
-7,538
-18% -$31.2K ﹤0.01% 4893
2024
Q2 		$149K Buy
41,393
+12,151
+42% +$39.4K ﹤0.01% 4938
2024
Q1 		$96K Buy
+29,242
New +$99K ﹤0.01% 5626
2023
Q1 		– Sell
-6,190
Closed -$5.57K – 9734
2022
Q4 		$4K Buy
6,190
+4,328
+232% +$3.55K ﹤0.01% 8229
2022
Q3 		$1K Sell
1,862
-69,124
-97% -$84.6K ﹤0.01% 9577
2022
Q2 		$79K Buy
70,986
+69,977
+6,935% +$54.2K ﹤0.01% 5885
2022
Q1 		$1K Sell
1,009
-110,074
-99% -$142K ﹤0.01% 10105
2021
Q4 		$177K Buy
111,083
+99,670
+873% +$199K ﹤0.01% 5368
2021
Q3 		$35K Sell
11,413
-5,122
-31% -$13.6K ﹤0.01% 7953
2021
Q2 		$52K Buy
16,535
+9,156
+124% +$30.7K ﹤0.01% 7603
2021
Q1 		$24K Buy
+7,379
New +$26.1K ﹤0.01% 7311

Other funds holding MREO

RCMNY
Rubric Capital Management (New York) New York $9.44B AUM 68.42% 1-Year Est. Return
EC
EcoR1 Capital San Francisco, California $2.36B AUM 204.53% 1-Year Est. Return
6CM
683 Capital Management New York $1.92B AUM 85.52% 1-Year Est. Return
Bank of America
Bank of America Charlotte, North Carolina $1.37T AUM 24.88% 1-Year Est. Return
DCM
Defilade Capital Management Emeryville, California $712M AUM
NM
Newtyn Management New York $936M AUM 27.23% 1-Year Est. Return
Millennium Management
Millennium Management New York $240B AUM 35.51% 1-Year Est. Return
TC
Tejara Capital London, United Kingdom $303M AUM 5.43% 1-Year Est. Return
UBS Group
UBS Group Zurich, Switzerland $666B AUM 30.12% 1-Year Est. Return
WANY
Wealthspire Advisors (New York) New York $12.7B AUM 17.31% 1-Year Est. Return

Simplex Trading's MREO Position: Q1 2026 in Review

Simplex Trading sold out of Mereo BioPharma (MREO) in Q1 2026, closing a stake of 419,477 shares — an estimated $180K sold.

Simplex Trading first reported a position in MREO in Q1 2021 and held it in 16 quarters. The position peaked at $545K in Q2 2025. 63 funds tracked by Wall St. Rank hold MREO as of Q1 2026.

  • Simplex Trading reported no remaining Mereo BioPharma position as of Q1 2026 after selling out during the quarter.
  • Simplex Trading sold 419,477 Mereo BioPharma shares in Q1 2026, an estimated $180K.
  • Simplex Trading first reported a position in Mereo BioPharma in Q1 2021 and held it in 16 quarters.
  • Simplex Trading's Mereo BioPharma position peaked at $545K in Q2 2025.
  • 63 funds tracked by Wall St. Rank held Mereo BioPharma as of Q1 2026.

Based on Simplex Trading's 13F filing for Q1 2026, filed 14 May 2026.