MREO

Mereo BioPharma
MREO

Overview Fund Activity

82 hedge funds and large institutions have $267M invested in Mereo BioPharma in 2025 Q2 according to their latest regulatory filings, with 11 funds opening new positions, 30 increasing their positions, 19 reducing their positions, and 17 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
82
Holders Change
-7
Holders Change %
-7.87%
% of All Funds
1.1%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.01%
New
11
Increased
30
Reduced
19
Closed
17
Calls
$8.29M
Puts
$3.35M
Net Calls
+$4.95M
Net Calls Change
+$3.2M

Top Buyers

1
FLSM
Frazier Life Sciences Management
California
$25.6M
2
Goldman Sachs
Goldman Sachs
New York
$8.37M
3
Aberdeen Group
Aberdeen Group
United Kingdom
$8.21M
4
Fidelity Investments
Fidelity Investments
Massachusetts
$4.01M
5
Citadel Advisors
Citadel Advisors
Florida
$2.06M

Top Sellers

1
Janus Henderson Group
Janus Henderson Group
United Kingdom
$48.1M
2
RSCM
Rock Springs Capital Management
Maryland
$12.1M
3
Adage Capital Partners
Adage Capital Partners
Massachusetts
$0
4
Morgan Stanley
Morgan Stanley
New York
$2.13M
5
UBS AM
UBS AM
Illinois
$0
Name Holding Trade Value Shares
Change 		Shares
Change %
Janus Henderson Group
1
Janus Henderson Group
United Kingdom
$48.1M -$13.7M -5,046,529 -22%
RCMNY
2
Rubric Capital Management (New York)
New York
$41.5M – – –
FLSM
3
Frazier Life Sciences Management
California
$25.6M +$4.39M +1,620,249 +21%
MP
4
Mangrove Partners
Connecticut
$23.4M – – –
DM
5
Deerfield Management
New York
$18.2M – – –
Alkeon Capital Management
6
Alkeon Capital Management
New York
$12.7M – – –
RSCM
7
Rock Springs Capital Management
Maryland
$12.1M -$6.01M -2,218,955 -33%
6CM
8
683 Capital Management
New York
$11.8M -$772K -285,000 -6%
CC
9
Clearline Capital
New York
$9.81M +$1.08M +400,269 +12%
Goldman Sachs
10
Goldman Sachs
New York
$8.37M +$2.61M +964,148 +45%
Aberdeen Group
11
Aberdeen Group
United Kingdom
$8.21M +$2.28M +840,518 +38%
TC
12
Tejara Capital
United Kingdom
$6.59M -$246K -90,887 -4%
Renaissance Technologies
13
Renaissance Technologies
New York
$4.01M +$352K +130,000 +10%
Fidelity Investments
14
Fidelity Investments
Massachusetts
$4.01M +$1.95M +719,400 +95%
SSA
15
Schonfeld Strategic Advisors
New York
$2.47M -$1.85M -681,416 -43%
Morgan Stanley
16
Morgan Stanley
New York
$2.13M -$3.78M -1,394,265 -64%
Marshall Wace
17
Marshall Wace
United Kingdom
$2.08M – – –
HP
18
HealthInvest Partners
Sweden
$2.07M +$1.02M +374,901 +96%
Citadel Advisors
19
Citadel Advisors
Florida
$2.06M +$1.13M +417,006 +121%
Two Sigma Investments
20
Two Sigma Investments
New York
$1.79M +$1.12M +413,952 +169%
SCM
21
Soleus Capital Management
Connecticut
$1.63M -$236K -87,242 -13%
Millennium Management
22
Millennium Management
New York
$1.61M +$545K +201,242 +51%
AGP
23
Artia Global Partners
Florida
$1.29M +$146K +54,002 +13%
BlackRock
24
BlackRock
New York
$1.23M +$491K +181,004 +66%
Hudson Bay Capital Management
25
Hudson Bay Capital Management
Connecticut
$1.22M – – –
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