MREO

Mereo BioPharma
MREO

Overview Fund Activity

89 hedge funds and large institutions have $250M invested in Mereo BioPharma in 2025 Q1 according to their latest regulatory filings, with 13 funds opening new positions, 27 increasing their positions, 21 reducing their positions, and 14 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
89
Holders Change
-1
Holders Change %
-1.11%
% of All Funds
1.21%
Holding in Top 10
1
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-50%
% of All Funds
0.01%
New
13
Increased
27
Reduced
21
Closed
14
Calls
$3.5M
Puts
$1.75M
Net Calls
+$1.75M
Net Calls Change
+$564K

Top Buyers

1
Janus Henderson Group
Janus Henderson Group
United Kingdom
+$12.9M
2
FLSM
Frazier Life Sciences Management
California
+$6.12M
3
Aberdeen Group
Aberdeen Group
United Kingdom
+$4.92M
4
SSA
Schonfeld Strategic Advisors
New York
+$2.47M
5
Fidelity Investments
Fidelity Investments
Massachusetts
+$1.71M

Top Sellers

1
Adage Capital Partners
Adage Capital Partners
Massachusetts
-$15.8M
2
Millennium Management
Millennium Management
New York
-$8.03M
3
RSCM
Rock Springs Capital Management
Maryland
-$6.56M
4
UBS Group
UBS Group
Switzerland
-$3.86M
5
Morgan Stanley
Morgan Stanley
New York
-$3.09M
Name Holding Trade Value Shares
Change 		Shares
Change %
Janus Henderson Group
1
Janus Henderson Group
United Kingdom
$52.4M +$12.9M +5,612,558 +33%
RCMNY
2
Rubric Capital Management (New York)
New York
$34.4M – – –
MP
3
Mangrove Partners
Connecticut
$19.4M – – –
FLSM
4
Frazier Life Sciences Management
California
$17.6M +$6.12M +2,722,084 +53%
DM
5
Deerfield Management
New York
$15.1M – – –
RSCM
6
Rock Springs Capital Management
Maryland
$15M -$6.56M -2,914,923 -30%
Alkeon Capital Management
7
Alkeon Capital Management
New York
$10.6M – – –
6CM
8
683 Capital Management
New York
$10.4M +$191K +85,000 +2%
CC
9
Clearline Capital
New York
$7.24M – – –
TC
10
Tejara Capital
United Kingdom
$5.67M +$460K +204,239 +9%
Aberdeen Group
11
Aberdeen Group
United Kingdom
$4.92M +$4.92M +2,188,354 New
Morgan Stanley
12
Morgan Stanley
New York
$4.9M -$3.09M -1,374,592 -39%
Goldman Sachs
13
Goldman Sachs
New York
$4.78M +$13.7K +6,068 +0.3%
Adage Capital Partners
14
Adage Capital Partners
Massachusetts
$3.83M -$15.8M -7,014,257 -80%
SSA
15
Schonfeld Strategic Advisors
New York
$3.58M +$2.47M +1,097,156 +222%
UBS AM
16
UBS AM
Illinois
$3.53M +$1.36M +604,200 +63%
Renaissance Technologies
17
Renaissance Technologies
New York
$3.04M +$362K +161,000 +14%
GPP
18
Great Point Partners
Connecticut
$2.87M +$281K +125,000 +11%
WP
19
Woodline Partners
California
$2.13M +$741K +329,202 +53%
UBS Group
20
UBS Group
Switzerland
$2.1M -$3.86M -1,716,119 -65%
PA
21
Perceptive Advisors
New York
$1.97M -$469K -208,551 -19%
IHAM
22
Integral Health Asset Management
New York
$1.8M -$450K -200,000 -20%
ACP
23
Acuta Capital Partners
California
$1.78M +$28.1K +12,507 +2%
Marshall Wace
24
Marshall Wace
United Kingdom
$1.73M -$222K -98,573 -11%
Fidelity Investments
25
Fidelity Investments
Massachusetts
$1.71M +$1.71M +759,100 New
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