Simplex Trading
MREO

Simplex Trading’s Mereo BioPharma MREO Stock Holding History

Simplex Trading’s Portfolio MREO Stock Details MREO Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$46.5K Sell
146,200
-56,900
-28% -$17.1K ﹤0.01% 6372
2026
Q1 		$67K Buy
203,100
+35,800
+21% +$15.4K ﹤0.01% 5537
2025
Q4 		$69.8K Buy
167,300
+120,100
+254% +$229K ﹤0.01% 5352
2025
Q3 		$97K Sell
47,200
-152,000
-76% -$280K ﹤0.01% 5780
2025
Q2 		$539K Buy
199,200
+142,300
+250% +$343K ﹤0.01% 3431
2025
Q1 		$128K Buy
56,900
+38,600
+211% +$109K ﹤0.01% 4801
2024
Q4 		$64K Sell
18,300
-45,300
-71% -$178K ﹤0.01% 5614
2024
Q3 		$261K Sell
63,600
-11,200
-15% -$46.3K ﹤0.01% 4264
2024
Q2 		$269K Buy
74,800
+19,700
+36% +$63.8K ﹤0.01% 4347
2024
Q1 		$181K Sell
55,100
-15,500
-22% -$52.5K ﹤0.01% 4966
2023
Q4 		$163K Sell
70,600
-8,500
-11% -$16.3K ﹤0.01% 4874
2023
Q3 		$102K Buy
79,100
+22,700
+40% +$30.1K ﹤0.01% 5066
2023
Q2 		$74K Buy
56,400
+23,000
+69% +$26.7K ﹤0.01% 5431
2023
Q1 		$23K Buy
33,400
+29,700
+803% +$26.7K ﹤0.01% 6786
2022
Q4 		$2K Sell
3,700
-31,900
-90% -$26.2K ﹤0.01% 8611
2022
Q3 		$30K Buy
35,600
+18,300
+106% +$22.4K ﹤0.01% 7078
2022
Q2 		$19K Buy
17,300
+16,100
+1,342% +$12.5K ﹤0.01% 7674
2022
Q1 		$1K Buy
+1,200
New +$1.55K ﹤0.01% 10104
2021
Q4 		– Sell
-7,800
Closed -$24K – 11054
2021
Q3 		$24K Hold
7,800
– – ﹤0.01% 8273
2021
Q2 		$24K Buy
7,800
+6,582
+540% +$22.1K ﹤0.01% 8430
2021
Q1 		$410K Buy
+1,218
New +$4.3K ﹤0.01% 3664

Other funds holding MREO

RCMNY
Rubric Capital Management (New York) New York $10.9B AUM 70.31% 1-Year Est. Return
6CM
683 Capital Management New York $2.04B AUM 94.26% 1-Year Est. Return
Bank of America
Bank of America Charlotte, North Carolina $1.55T AUM 33.47% 1-Year Est. Return
DCM
Defilade Capital Management Emeryville, California $747M AUM
NM
Newtyn Management New York $801M AUM 23.14% 1-Year Est. Return
TC
Tejara Capital London, United Kingdom $243M AUM 9.84% 1-Year Est. Return
UBS Group
UBS Group Zurich, Switzerland $786B AUM 40.34% 1-Year Est. Return
Two Sigma Investments
Two Sigma Investments New York $138B AUM 41.87% 1-Year Est. Return
EC
EcoR1 Capital San Francisco, California $2.06B AUM 215.32% 1-Year Est. Return
Jane Street
Jane Street New York $1.21T AUM 78.12% 1-Year Est. Return

Simplex Trading's MREO Position: Q2 2026 in Review

Simplex Trading opened a new position in Mereo BioPharma (MREO) in Q2 2026: 18,780 shares worth $5.97K. The stake represents ﹤0.01% of the portfolio and ranks #8066 among its holdings. This is a return to the name: Simplex Trading previously reported a position in MREO as recently as Q4 2025.

Simplex Trading first reported a position in MREO in Q1 2021 and has held it in 17 quarters since. The position peaked at $545K in Q2 2025. 61 funds tracked by Wall St. Rank hold MREO as of Q2 2026.

  • Simplex Trading held 18,780 shares of Mereo BioPharma worth $5.97K as of Q2 2026.
  • Mereo BioPharma was a new Simplex Trading position in Q2 2026.
  • Mereo BioPharma made up ﹤0.01% of Simplex Trading's portfolio in Q2 2026, its #8066 holding.
  • Simplex Trading first reported a position in Mereo BioPharma in Q1 2021 and has held it in 17 quarters since.
  • Simplex Trading's Mereo BioPharma position peaked at $545K in Q2 2025.
  • 61 funds tracked by Wall St. Rank held Mereo BioPharma as of Q2 2026.

Based on Simplex Trading's 13F filing for Q2 2026, filed 12 Aug 2026.