Simplex Trading
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Simplex Trading’s Denali Therapeutics DNLI Stock Holding History

Simplex Trading’s Portfolio DNLI Stock Details DNLI Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$1.17M Buy
61,100
+60,700
+15,175% +$1.21M ﹤0.01% 2320
2025
Q4 		$6.6K Sell
400
-700
-64% -$11.8K ﹤0.01% 7265
2025
Q3 		$15K Sell
1,100
-28,600
-96% -$411K ﹤0.01% 7578
2025
Q2 		$415K Buy
+29,700
New +$418K ﹤0.01% 3710
2024
Q4 		– Sell
-12,500
Closed -$364K – 8725
2024
Q3 		$364K Sell
12,500
-900
-7% -$22.3K ﹤0.01% 3931
2024
Q2 		$311K Sell
13,400
-15,700
-54% -$301K ﹤0.01% 4179
2024
Q1 		$597K Buy
29,100
+29,000
+29,000% +$545K ﹤0.01% 3670
2023
Q4 		$2K Buy
+100
New +$1.98K ﹤0.01% 8247
2023
Q2 		– Sell
-2,300
Closed -$52K – 9168
2023
Q1 		$52K Buy
2,300
+2,200
+2,200% +$60.5K ﹤0.01% 5875
2022
Q4 		$2K Hold
100
– – ﹤0.01% 8552
2022
Q3 		$3K Sell
100
-100
-50% -$3.25K ﹤0.01% 9070
2022
Q2 		$5K Buy
+200
New +$5.24K ﹤0.01% 8812
2022
Q1 		– Sell
-20,400
Closed -$909K – 10577
2021
Q4 		$909K Buy
20,400
+19,800
+3,300% +$938K ﹤0.01% 2994
2021
Q3 		$46K Hold
600
– – ﹤0.01% 7595
2021
Q2 		$47K Buy
600
+490
+445% +$30.3K ﹤0.01% 7700
2021
Q1 		$628K Buy
+110
New +$7.36K ﹤0.01% 3029
2020
Q2 		– Sell
-25
Closed -$43K – 7737
2020
Q1 		$43K Sell
25
-21
-46% -$438 ﹤0.01% 5285
2019
Q4 		$80K Sell
46
-117
-72% -$1.95K ﹤0.01% 4730
2019
Q3 		$249K Buy
+163
New +$3.11K ﹤0.01% 3341

Other funds holding DNLI

BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
Baillie Gifford & Co
Baillie Gifford & Co Edinburgh, United Kingdom $97.9B AUM 20.73% 1-Year Est. Return
T. Rowe Price Investment Management
T. Rowe Price Investment Management Baltimore, Maryland $145B AUM 22.78% 1-Year Est. Return
Temasek Holdings
Temasek Holdings Singapore $30.5B AUM 13.98% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
VPM
Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM
Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
UBS AM
UBS AM Chicago, Illinois $481B AUM 26.39% 1-Year Est. Return
Goldman Sachs
Goldman Sachs New York $871B AUM 31.28% 1-Year Est. Return

Simplex Trading's DNLI Position: Q1 2026 in Review

Simplex Trading opened a new position in Denali Therapeutics (DNLI) in Q1 2026: 12,315 shares worth $236K. The stake represents ﹤0.01% of the portfolio and ranks #4097 among its holdings. This is a return to the name: Simplex Trading previously reported a position in DNLI as recently as Q3 2025.

Simplex Trading first reported a position in DNLI in Q3 2018 and has held it in 18 quarters since. The position peaked at $418K in Q4 2021. 268 funds tracked by Wall St. Rank hold DNLI as of Q1 2026.

  • Simplex Trading held 12,315 shares of Denali Therapeutics worth $236K as of Q1 2026.
  • Denali Therapeutics was a new Simplex Trading position in Q1 2026.
  • Denali Therapeutics made up ﹤0.01% of Simplex Trading's portfolio in Q1 2026, its #4097 holding.
  • Simplex Trading first reported a position in Denali Therapeutics in Q3 2018 and has held it in 18 quarters since.
  • Simplex Trading's Denali Therapeutics position peaked at $418K in Q4 2021.
  • 268 funds tracked by Wall St. Rank held Denali Therapeutics as of Q1 2026.

Based on Simplex Trading's 13F filing for Q1 2026, filed 14 May 2026.