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Denali Therapeutics
DNLI

Overview Fund Activity

230 hedge funds and large institutions have $1.93B invested in Denali Therapeutics in 2025 Q2 according to their latest regulatory filings, with 46 funds opening new positions, 83 increasing their positions, 64 reducing their positions, and 36 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
230
Holders Change
+9
Holders Change %
+4.07%
% of All Funds
3.08%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.01%
New
46
Increased
83
Reduced
64
Closed
36
Calls
$2.08M
Puts
$630K
Net Calls
+$1.45M
Net Calls Change
+$1.12M

Top Buyers

1
T. Rowe Price Investment Management
T. Rowe Price Investment Management
Maryland
+$45.4M
2
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
+$31M
3
Point72 Asset Management
Point72 Asset Management
Connecticut
+$31M
4
MCM
Masters Capital Management
Georgia
+$8.39M
5
Voloridge Investment Management
Voloridge Investment Management
Florida
+$6.56M

Top Sellers

1
Wellington Management Group
Wellington Management Group
Massachusetts
-$80.4M
2
BlackRock
BlackRock
New York
-$24.9M
3
CCM
Camber Capital Management
Massachusetts
-$11.9M
4
Marshall Wace
Marshall Wace
United Kingdom
-$11M
5
Squarepoint
Squarepoint
New York
-$9.34M
Name Holding Trade Value Shares
Change 		Shares
Change %
BlackRock
1
BlackRock
New York
$169M -$24.9M -1,781,611 -13%
Baillie Gifford & Co
2
Baillie Gifford & Co
United Kingdom
$167M -$1.88M -134,717 -1%
Vanguard Group
3
Vanguard Group
Pennsylvania
$165M +$154K +10,978 +0.1%
Fidelity Investments
4
Fidelity Investments
Massachusetts
$105M +$1.75M +125,114 +2%
T. Rowe Price Associates
5
T. Rowe Price Associates
Maryland
$92.1M +$31M +2,215,061 +51%
UBS AM
6
UBS AM
Illinois
$87.6M -$7.06M -504,639 -7%
Wellington Management Group
7
Wellington Management Group
Massachusetts
$79.2M -$80.4M -5,744,865 -50%
Temasek Holdings
8
Temasek Holdings
Singapore
$74.9M – – –
Capital Research Global Investors
9
Capital Research Global Investors
California
$66.5M -$204K -14,558 -0.3%
State Street
10
State Street
Massachusetts
$63.2M +$801K +57,237 +1%
Norges Bank
11
Norges Bank
Norway
$55.2M +$55.2M +3,947,387 New
CM
12
Crestline Management
Texas
$54M -$4.2M -300,000 -7%
BBA
13
Baker Bros. Advisors
New York
$52.2M – – –
T. Rowe Price Investment Management
14
T. Rowe Price Investment Management
Maryland
$45.4M +$45.4M +3,246,934 New
Geode Capital Management
15
Geode Capital Management
Massachusetts
$44.4M +$1.89M +135,129 +4%
AllianceBernstein
16
AllianceBernstein
Tennessee
$43.9M -$241K -17,247 -0.5%
Dimensional Fund Advisors
17
Dimensional Fund Advisors
Texas
$33.8M +$4.37M +312,072 +15%
Point72 Asset Management
18
Point72 Asset Management
Connecticut
$31M +$31M +2,213,947 New
Goldman Sachs
19
Goldman Sachs
New York
$26.1M +$2.7M +193,246 +12%
Fisher Asset Management
20
Fisher Asset Management
Washington
$21.2M +$2.11M +151,032 +11%
Marshall Wace
21
Marshall Wace
United Kingdom
$19.7M -$11M -783,172 -36%
Morgan Stanley
22
Morgan Stanley
New York
$18.4M +$817K +58,413 +5%
Citadel Advisors
23
Citadel Advisors
Florida
$17.5M +$1.11M +79,270 +7%
Northern Trust
24
Northern Trust
Illinois
$16.8M +$973K +69,536 +6%
Principal Financial Group
25
Principal Financial Group
Iowa
$15M -$120K -8,595 -0.8%
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