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Denali Therapeutics

213 hedge funds and large institutions have $3.8B invested in Denali Therapeutics in 2021 Q4 according to their latest regulatory filings, with 29 funds opening new positions, 86 increasing their positions, 62 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed

39% more repeat investments, than reductions

Existing positions increased: 86 | Existing positions reduced: 62

7% more first-time investments, than exits

New positions opened: 29 | Existing positions closed: 27

0.08% more ownership

Funds ownership: 69.74%69.82% (+0.08%)

0% less funds holding

Funds holding: 214213 (-1)

11% less capital invested

Capital invested by funds: $4.28B → $3.8B (-$480M)

60% less funds holding in top 10

Funds holding in top 10: 52 (-3)

77% less call options, than puts

Call options by funds: $2.6M | Put options by funds: $11.3M

Holders
213
Holders Change
-1
Holders Change %
-0.47%
% of All Funds
3.28%
Holding in Top 10
2
Holding in Top 10 Change
-3
Holding in Top 10 Change %
-60%
% of All Funds
0.03%
New
29
Increased
86
Reduced
62
Closed
27
Calls
$2.6M
Puts
$11.3M
Net Calls
-$8.68M
Net Calls Change
-$15.9M
Name Holding Trade Value Shares
Change
Change in
Stake
Baillie Gifford & Co
1
Baillie Gifford & Co
United Kingdom
$672M +$2.21M +46,565 +0.3%
Vanguard Group
2
Vanguard Group
Pennsylvania
$364M -$329K -6,953 -0.1%
BlackRock
3
BlackRock
New York
$362M +$26.1M +549,985 +7%
CM
4
Crestline Management
Texas
$344M
Temasek Holdings
5
Temasek Holdings
Singapore
$239M
T. Rowe Price Associates
6
T. Rowe Price Associates
Maryland
$207M -$5.81M -122,532 -3%
State Street
7
State Street
Massachusetts
$135M +$10.9M +229,437 +8%
Fidelity Investments
8
Fidelity Investments
Massachusetts
$132M +$13.1M +276,042 +10%
GGHC
9
Gilder Gagnon Howe & Co
New York
$129M +$4.6M +97,120 +3%
FP
10
Flagship Pioneering
Massachusetts
$117M -$5.23M -110,295 -4%
CS
11
Credit Suisse
Switzerland
$87.6M -$892K -18,825 -0.9%
Geode Capital Management
12
Geode Capital Management
Massachusetts
$72.6M +$1.02M +21,473 +1%
CC
13
Casdin Capital
New York
$66.9M -$9.48M -200,000 -12%
PAMS
14
Pictet Asset Management (Switzerland)
Switzerland
$44.5M +$6.16M +130,117 +15%
BAMCO Inc
15
BAMCO Inc
New York
$44.4M -$6.24M -131,615 -12%
Northern Trust
16
Northern Trust
Illinois
$42.8M +$349K +7,364 +0.8%
Bank of New York Mellon
17
Bank of New York Mellon
New York
$41.6M +$26.3M +555,873 +148%
Norges Bank
18
Norges Bank
Norway
$37.7M -$343K -7,247 -0.8%
Dimensional Fund Advisors
19
Dimensional Fund Advisors
Texas
$34.4M +$6.51M +137,462 +22%
Federated Hermes
20
Federated Hermes
Pennsylvania
$32.8M +$18.8M +396,272 +117%
Charles Schwab
21
Charles Schwab
California
$32M +$637K +13,438 +2%
AG
22
Artal Group
Luxembourg
$26.8M +$4.74M +100,000 +20%
American Century Companies
23
American Century Companies
Missouri
$23.9M +$8.87M +187,295 +54%
Artisan Partners
24
Artisan Partners
Wisconsin
$23.3M -$1.4M -29,579 -5%
Citadel Advisors
25
Citadel Advisors
Florida
$21.7M +$20M +422,672 +671%