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Denali Therapeutics

190 hedge funds and large institutions have $2.8B invested in Denali Therapeutics in 2022 Q1 according to their latest regulatory filings, with 19 funds opening new positions, 68 increasing their positions, 69 reducing their positions, and 40 closing their positions.

New
Increased
Maintained
Reduced
Closed

0.82% more ownership

Funds ownership: 69.82%70.64% (+0.82%)

0% more funds holding in top 10

Funds holding in top 10: 22 (0)

1% less repeat investments, than reductions

Existing positions increased: 68 | Existing positions reduced: 69

11% less funds holding

Funds holding: 213190 (-23)

26% less capital invested

Capital invested by funds: $3.8B → $2.8B (-$998M)

53% less first-time investments, than exits

New positions opened: 19 | Existing positions closed: 40

55% less call options, than puts

Call options by funds: $818K | Put options by funds: $1.8M

Holders
190
Holders Change
-23
Holders Change %
-10.8%
% of All Funds
3%
Holding in Top 10
2
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.03%
New
19
Increased
68
Reduced
69
Closed
40
Calls
$818K
Puts
$1.8M
Net Calls
-$986K
Net Calls Change
+$7.7M
Name Holding Trade Value Shares
Change
Change in
Stake
Baillie Gifford & Co
1
Baillie Gifford & Co
United Kingdom
$482M -$2.61M -75,949 -0.5%
BlackRock
2
BlackRock
New York
$263M +$2.58M +74,918 +0.9%
Vanguard Group
3
Vanguard Group
Pennsylvania
$261M -$1.7M -49,500 -0.6%
CM
4
Crestline Management
Texas
$240M -$8.41M -244,307 -3%
Temasek Holdings
5
Temasek Holdings
Singapore
$173M
T. Rowe Price Associates
6
T. Rowe Price Associates
Maryland
$158M +$9.91M +287,992 +6%
State Street
7
State Street
Massachusetts
$123M +$27.5M +799,221 +26%
Fidelity Investments
8
Fidelity Investments
Massachusetts
$94.7M -$266K -7,736 -0.3%
FP
9
Flagship Pioneering
Massachusetts
$84.3M
GGHC
10
Gilder Gagnon Howe & Co
New York
$84.3M -$9.67M -280,897 -10%
CS
11
Credit Suisse
Switzerland
$63M -$175K -5,074 -0.3%
Geode Capital Management
12
Geode Capital Management
Massachusetts
$52.5M +$71.6K +2,080 +0.1%
Bank of New York Mellon
13
Bank of New York Mellon
New York
$51.8M +$23.3M +676,625 +73%
CC
14
Casdin Capital
New York
$48.3M
PAMS
15
Pictet Asset Management (Switzerland)
Switzerland
$32.9M +$858K +24,943 +2%
YCM
16
Yiheng Capital Management
California
$32.6M +$23.4M +679,500 +203%
Northern Trust
17
Northern Trust
Illinois
$29.2M -$1.82M -52,861 -6%
Federated Hermes
18
Federated Hermes
Pennsylvania
$29.1M +$5.84M +169,813 +23%
Dimensional Fund Advisors
19
Dimensional Fund Advisors
Texas
$28.3M +$3.65M +106,027 +14%
Norges Bank
20
Norges Bank
Norway
$27.2M -$1.58K -46 -0%
Citadel Advisors
21
Citadel Advisors
Florida
$24.2M +$9.15M +265,920 +55%
Morgan Stanley
22
Morgan Stanley
New York
$22.7M +$14.4M +418,397 +146%
Charles Schwab
23
Charles Schwab
California
$22.7M -$445K -12,939 -2%
BAMCO Inc
24
BAMCO Inc
New York
$21.1M -$11.7M -340,956 -34%
AG
25
Artal Group
Luxembourg
$19.3M

DNLI Hedge Fund Activity: Q1 2022 in Review

190 of the 6,340 institutional investors tracked by Wall St. Rank reported a position in Denali Therapeutics (DNLI) for Q1 2022, worth a combined $2.8B — down 26% from $3.8B a quarter earlier.

Sellers outnumbered buyers: 40 funds closed out of DNLI and 19 opened new positions — a net loss of 21 holders — while 69 trimmed existing stakes and 68 added.

The largest buyer was State Street, adding an estimated $27.5M. The largest seller was BAMCO Inc, cutting an estimated $11.7M.

  • 190 institutional investors held Denali Therapeutics (DNLI) as of Q1 2022, down from 213 in Q4 2021.
  • Funds reported $2.8B of Denali Therapeutics stock for Q1 2022, down 26% quarter-over-quarter.
  • 19 funds opened new Denali Therapeutics positions in Q1 2022 and 40 closed out, a net change of -21 holders.
  • The largest Denali Therapeutics buyer in Q1 2022 was State Street, an estimated $27.5M added.
  • The largest Denali Therapeutics seller in Q1 2022 was BAMCO Inc, an estimated $11.7M sold.

Based on aggregated 13F filings for Q1 2022.