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Denali Therapeutics
DNLI

Overview Fund Activity

221 hedge funds and large institutions have $1.81B invested in Denali Therapeutics in 2025 Q1 according to their latest regulatory filings, with 36 funds opening new positions, 73 increasing their positions, 80 reducing their positions, and 35 closing their positions.

Holders
221
Holders Change
-2
Holders Change %
-0.9%
% of All Funds
3%
Holding in Top 10
1
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-50%
% of All Funds
0.01%
New
36
Increased
73
Reduced
80
Closed
35
Calls
$848K
Puts
$515K
Net Calls
+$333K
Net Calls Change
-$267K

Top Buyers

1
UBS AM
1
UBS AM
Illinois
$92M
2
Wellington Management Group
2
Wellington Management Group
Massachusetts
$155M
3
T. Rowe Price Associates
3
T. Rowe Price Associates
Maryland
$59.4M
4
Millennium Management
4
Millennium Management
New York
$20.3M
5
Squarepoint
5
Squarepoint
New York
$9.34M

Top Sellers

1
Norges Bank
1
Norges Bank
Norway
$0
2
CCM
2
Camber Capital Management
Massachusetts
$17M
3
Point72 Asset Management
3
Point72 Asset Management
Connecticut
$0
4
Capital Research Global Investors
4
Capital Research Global Investors
California
$64.8M
5
Fidelity Investments
5
Fidelity Investments
Massachusetts
$101M
Name Market Value Shares Shares
Change 		Shares
Change %
BlackRock
1
BlackRock
New York
$188M 13,834,956 -85,289 -0.6%
Baillie Gifford & Co
2
Baillie Gifford & Co
United Kingdom
$164M 12,090,040 -223,891 -2%
Vanguard Group
3
Vanguard Group
Pennsylvania
$160M 11,799,757 -221,473 -2%
Wellington Management Group
4
Wellington Management Group
Massachusetts
$155M 11,409,598 +1,561,647 +16%
Fidelity Investments
5
Fidelity Investments
Massachusetts
$101M 7,413,354 -606,392 -8%
UBS AM
6
UBS AM
Illinois
$92M 6,766,916 +3,184,042 +89%
Temasek Holdings
7
Temasek Holdings
Singapore
$72.8M 5,355,832 – –
Capital Research Global Investors
8
Capital Research Global Investors
California
$64.8M 4,765,137 -712,074 -13%
State Street
9
State Street
Massachusetts
$60.6M 4,460,757 -84,216 -2%
T. Rowe Price Associates
10
T. Rowe Price Associates
Maryland
$59.4M 4,367,234 +1,308,619 +43%
CM
11
Crestline Management
Texas
$56.6M 4,160,732 -150,000 -3%
BBA
12
Baker Bros. Advisors
New York
$50.7M 3,731,695 – –
AllianceBernstein
13
AllianceBernstein
Tennessee
$42.9M 3,154,387 -161,255 -5%
Geode Capital Management
14
Geode Capital Management
Massachusetts
$41.3M 3,037,176 +101,893 +3%
Marshall Wace
15
Marshall Wace
United Kingdom
$29.8M 2,188,422 +399,685 +22%
Dimensional Fund Advisors
16
Dimensional Fund Advisors
Texas
$28.6M 2,100,856 +245,820 +13%
Goldman Sachs
17
Goldman Sachs
New York
$22.7M 1,672,078 +614,555 +58%
Millennium Management
18
Millennium Management
New York
$20.3M 1,493,068 +1,088,844 +269%
Fisher Asset Management
19
Fisher Asset Management
Washington
$18.6M 1,364,959 +572,460 +72%
Morgan Stanley
20
Morgan Stanley
New York
$17M 1,253,603 +24,463 +2%
CCM
21
Camber Capital Management
Massachusetts
$17M 1,250,000 -1,000,000 -44%
Citadel Advisors
22
Citadel Advisors
Florida
$15.9M 1,169,683 +339,772 +41%
Northern Trust
23
Northern Trust
Illinois
$15.4M 1,132,173 -69,345 -6%
Bank of New York Mellon
24
Bank of New York Mellon
New York
$15M 1,103,892 -139,095 -11%
Principal Financial Group
25
Principal Financial Group
Iowa
$14.7M 1,081,578 -49,385 -4%
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