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Denali Therapeutics

216 hedge funds and large institutions have $4.59B invested in Denali Therapeutics in 2021 Q1 according to their latest regulatory filings, with 41 funds opening new positions, 78 increasing their positions, 69 reducing their positions, and 26 closing their positions.

New
Increased
Maintained
Reduced
Closed

77% more call options, than puts

Call options by funds: $8.56M | Put options by funds: $4.85M

58% more first-time investments, than exits

New positions opened: 41 | Existing positions closed: 26

13% more repeat investments, than reductions

Existing positions increased: 78 | Existing positions reduced: 69

6% more funds holding

Funds holding: 204216 (+12)

0% more funds holding in top 10

Funds holding in top 10: 55 (0)

7.4% less ownership

Funds ownership: 73.91%66.51% (-7.4%)

25% less capital invested

Capital invested by funds: $6.13B → $4.59B (-$1.53B)

Holders
216
Holders Change
+12
Holders Change %
+5.88%
% of All Funds
3.79%
Holding in Top 10
5
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.09%
New
41
Increased
78
Reduced
69
Closed
26
Calls
$8.56M
Puts
$4.85M
Net Calls
+$3.71M
Net Calls Change
-$19.8M
Name Holding Trade Value Shares
Change
Change in
Stake
Baillie Gifford & Co
1
Baillie Gifford & Co
United Kingdom
$742M +$53.9M +804,941 +7%
CM
2
Crestline Management
Texas
$570M -$634M -9,477,664 -49%
Vanguard Group
3
Vanguard Group
Pennsylvania
$466M +$16.2M +241,393 +3%
BlackRock
4
BlackRock
New York
$375M +$12.6M +188,374 +3%
T. Rowe Price Associates
5
T. Rowe Price Associates
Maryland
$346M -$27.2M -406,547 -6%
Temasek Holdings
6
Temasek Holdings
Singapore
$252M
GGHC
7
Gilder Gagnon Howe & Co
New York
$172M -$14.4M -215,290 -7%
FP
8
Flagship Pioneering
Massachusetts
$156M
Fidelity Investments
9
Fidelity Investments
Massachusetts
$153M -$55.3M -826,509 -24%
State Street
10
State Street
Massachusetts
$115M -$3.37M -50,406 -2%
CS
11
Credit Suisse
Switzerland
$112M +$37.2M +555,243 +40%
CC
12
Casdin Capital
New York
$91.9M +$20.1M +300,000 +23%
Geode Capital Management
13
Geode Capital Management
Massachusetts
$71.5M +$6.56M +97,930 +8%
BAMCO Inc
14
BAMCO Inc
New York
$69.1M +$9.8M +146,418 +14%
Northern Trust
15
Northern Trust
Illinois
$43M -$1.61M -24,111 -3%
Goldman Sachs
16
Goldman Sachs
New York
$37M -$3.65M -54,543 -8%
Norges Bank
17
Norges Bank
Norway
$34.1M -$17.3M -258,663 -30%
Artisan Partners
18
Artisan Partners
Wisconsin
$32.3M +$9.54M +142,513 +34%
Charles Schwab
19
Charles Schwab
California
$32.3M +$4.84M +72,318 +15%
AG
20
Artal Group
Luxembourg
$28.6M +$6.69M +100,000 +25%
Two Sigma Investments
21
Two Sigma Investments
New York
$28.4M +$15.8M +235,633 +90%
PAMU
22
Pictet Asset Management (UK)
United Kingdom
$27.9M -$10.1M -150,961 -24%
WA
23
Wasatch Advisors
Utah
$27.3M -$190K -2,842 -0.6%
Morgan Stanley
24
Morgan Stanley
New York
$26.4M +$16.2M +242,732 +111%
Two Sigma Advisers
25
Two Sigma Advisers
New York
$25.8M +$12.7M +190,200 +73%

DNLI Hedge Fund Activity: Q1 2021 in Review

216 of the 5,695 institutional investors tracked by Wall St. Rank reported a position in Denali Therapeutics (DNLI) for Q1 2021, worth a combined $4.59B — down 25% from $6.13B a quarter earlier.

Buyers outnumbered sellers: 41 funds opened new DNLI positions and 26 closed out — a net gain of 15 holders — while 78 added to existing stakes and 69 trimmed.

The largest buyer was Baillie Gifford & Co, adding an estimated $53.9M. The largest seller was Crestline Management, cutting an estimated $634M.

  • 216 institutional investors held Denali Therapeutics (DNLI) as of Q1 2021, up from 204 in Q4 2020.
  • Funds reported $4.59B of Denali Therapeutics stock for Q1 2021, down 25% quarter-over-quarter.
  • 41 funds opened new Denali Therapeutics positions in Q1 2021 and 26 closed out, a net change of +15 holders.
  • The largest Denali Therapeutics buyer in Q1 2021 was Baillie Gifford & Co, an estimated $53.9M added.
  • The largest Denali Therapeutics seller in Q1 2021 was Crestline Management, an estimated $634M sold.

Based on aggregated 13F filings for Q1 2021.