Simplex Trading
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Simplex Trading’s Denali Therapeutics DNLI Stock Holding History

Simplex Trading’s Portfolio DNLI Stock Details DNLI Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$616K Buy
23,952
+11,637
+94% +$239K ﹤0.01% 3339
2026
Q1 		$236K Buy
+12,315
New +$245K ﹤0.01% 4097
2025
Q4 		– Sell
-41
Closed -$692 – 8880
2025
Q3 		$0 Sell
41
-2,461
-98% -$35.4K ﹤0.01% 9252
2025
Q2 		$35K Buy
+2,502
New +$35.2K ﹤0.01% 6253
2024
Q4 		– Sell
-3,475
Closed -$89K – 8724
2024
Q3 		$101K Sell
3,475
-1,459
-30% -$36.2K ﹤0.01% 5220
2024
Q2 		$114K Buy
4,934
+6
+0.1% +$115 ﹤0.01% 5244
2024
Q1 		$101K Buy
+4,928
New +$92.6K ﹤0.01% 5558
2023
Q2 		– Sell
-6,293
Closed -$177K – 9167
2023
Q1 		$144K Buy
6,293
+4,911
+355% +$135K ﹤0.01% 4727
2022
Q4 		$38K Sell
1,382
-2,068
-60% -$61.5K ﹤0.01% 6197
2022
Q3 		$105K Buy
+3,450
New +$112K ﹤0.01% 5452
2022
Q1 		– Sell
-9,376
Closed -$323K – 10576
2021
Q4 		$418K Buy
+9,376
New +$444K ﹤0.01% 4060
2021
Q2 		– Sell
-449
Closed -$27.8K – 10144
2021
Q1 		$25K Buy
+449
New +$30.1K ﹤0.01% 7265
2020
Q3 		– Sell
-81
Closed – – 7915
2020
Q2 		$0 Sell
81
-2,522
-97% -$59.3K ﹤0.01% 7736
2020
Q1 		$45K Sell
2,603
-4,512
-63% -$94.1K ﹤0.01% 5234
2019
Q4 		$123K Sell
7,115
-700
-9% -$11.7K ﹤0.01% 4294
2019
Q3 		$119K Buy
7,815
+7,695
+6,413% +$147K ﹤0.01% 4125
2019
Q2 		$2K Sell
120
-423
-78% -$9.48K ﹤0.01% 6739
2019
Q1 		$12K Buy
+543
New +$11.4K ﹤0.01% 6039
2018
Q4 		– Sell
-1,114
Closed -$24K – 7154
2018
Q3 		$24K Buy
+1,114
New +$18.4K ﹤0.01% 5809

Other funds holding DNLI

T. Rowe Price Investment Management
T. Rowe Price Investment Management Baltimore, Maryland $153B AUM 38.14% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
Baillie Gifford & Co
Baillie Gifford & Co Edinburgh, United Kingdom $110B AUM 4.8% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return
Temasek Holdings
Temasek Holdings Singapore $37.3B AUM 12.6% 1-Year Est. Return
Vanguard Portfolio Management
Vanguard Portfolio Management Malvern, Pennsylvania $2.22T AUM
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return
Goldman Sachs
Goldman Sachs New York $1.15T AUM 47.82% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.88T AUM 44.46% 1-Year Est. Return

Simplex Trading's DNLI Position: Q2 2026 in Review

Simplex Trading increased its Denali Therapeutics (DNLI) stake by 94% in Q2 2026, buying an estimated $239K and bringing the position to 23,952 shares worth $616K. The position accounts for ﹤0.01% of the portfolio, ranked #3339.

Simplex Trading first reported a position in DNLI in Q3 2018 and has held it in 19 quarters since. 292 funds tracked by Wall St. Rank hold DNLI as of Q2 2026.

  • Simplex Trading held 23,952 shares of Denali Therapeutics worth $616K as of Q2 2026.
  • Simplex Trading bought 11,637 Denali Therapeutics shares in Q2 2026, an estimated $239K.
  • Denali Therapeutics made up ﹤0.01% of Simplex Trading's portfolio in Q2 2026, its #3339 holding.
  • Simplex Trading first reported a position in Denali Therapeutics in Q3 2018 and has held it in 19 quarters since.
  • 292 funds tracked by Wall St. Rank held Denali Therapeutics as of Q2 2026.

Based on Simplex Trading's 13F filing for Q2 2026, filed 12 Aug 2026.