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Principal Securities’s Prime Medicine PRME Stock Holding History

Principal Securities’s Portfolio PRME Stock Details PRME Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q4 		– Sell
-200
Closed -$1.11K – 2955
2025
Q3 		$1.11K Sell
200
-80
-29% -$325 ﹤0.01% 3388
2025
Q2 		$692 Hold
280
– – ﹤0.01% 3421
2025
Q1 		$818 Hold
280
– – ﹤0.01% 3258
2024
Q4 		$818 Hold
280
– – ﹤0.01% 3251
2024
Q3 		$1.08K Buy
280
+115
+70% +$533 ﹤0.01% 3120
2024
Q2 		$848 Sell
165
-32
-16% -$194 ﹤0.01% 3102
2024
Q1 		$1.38K Sell
197
-55
-22% -$417 ﹤0.01% 2963
2023
Q4 		$2.23K Buy
+252
New +$1.94K ﹤0.01% 2779

Other funds holding PRME

AI
Alphabet Inc Mountain View, California $4.02B AUM 215.74% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
Vanguard Group
Vanguard Group Malvern, Pennsylvania $6.9T AUM 27.45% 1-Year Est. Return
T. Rowe Price Investment Management
T. Rowe Price Investment Management Baltimore, Maryland $145B AUM 22.78% 1-Year Est. Return
AIM
ARK Investment Management St. Petersburg, Florida $12.9B AUM 64.92% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
Sumitomo Mitsui Trust Group
Sumitomo Mitsui Trust Group Minato-Ku, Tokyo, Japan $154B AUM 29.96% 1-Year Est. Return
NAMA
Nikko Asset Management Americas New York $7.07B AUM 50.91% 1-Year Est. Return
CC
Casdin Capital New York $1.32B AUM 76.62% 1-Year Est. Return
Balyasny Asset Management
Balyasny Asset Management Chicago, Illinois $77.1B AUM 42.89% 1-Year Est. Return

Principal Securities's PRME Position: Q4 2025 in Review

Principal Securities sold out of Prime Medicine (PRME) in Q4 2025, closing a stake of 200 shares — an estimated $1.11K sold.

Principal Securities first reported a position in PRME in Q4 2023 and held it in 8 quarters. The position peaked at $2.23K in Q4 2023. 183 funds tracked by Wall St. Rank hold PRME as of Q4 2025.

  • Principal Securities reported no remaining Prime Medicine position as of Q4 2025 after selling out during the quarter.
  • Principal Securities sold 200 Prime Medicine shares in Q4 2025, an estimated $1.11K.
  • Principal Securities first reported a position in Prime Medicine in Q4 2023 and held it in 8 quarters.
  • Principal Securities's Prime Medicine position peaked at $2.23K in Q4 2023.
  • 183 funds tracked by Wall St. Rank held Prime Medicine as of Q4 2025.

Based on Principal Securities's 13F filing for Q4 2025, filed 12 Feb 2026.