PAI

Palo Alto Investors Portfolio holdings

AUM $470M
1-Year Return 2.57%
This Quarter Return
+44.94%
1 Year Return
+2.57%
3 Year Return
+93.77%
5 Year Return
+190.64%
10 Year Return
+955.02%
AUM
$1.82B
AUM Growth
+$315M
Cap. Flow
-$136M
Cap. Flow %
-7.48%
Top 10 Hldgs %
68.81%
Holding
39
New
2
Increased
2
Reduced
21
Closed
2

Top Buys

1
CLVS
Clovis Oncology, Inc.
CLVS
+$3.5M
2
FOLD icon
Amicus Therapeutics
FOLD
+$2.44M
3
RVNC
Revance Therapeutics, Inc.
RVNC
+$1.44M
4
ITCI
Intra-Cellular Therapies Inc.
ITCI
+$1.28M

Top Sells

1
ALDR
Alder Biopharmaceuticals, Inc.
ALDR
+$35.1M
2
BMRN icon
BioMarin Pharmaceuticals
BMRN
+$15.9M
3
ABMD
Abiomed Inc
ABMD
+$15.4M
4
UTHR icon
United Therapeutics
UTHR
+$11.9M
5
ACAD icon
Acadia Pharmaceuticals
ACAD
+$11.6M

Sector Composition

1 Healthcare 84.41%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
ZGNX
26
DELISTED
Zogenix, Inc.
ZGNX
$1.54M 0.08%
29,500
– –
ALIM
27
DELISTED
Alimera Sciences, Inc.
ALIM
$1.52M 0.08%
200,919
-1
-0% -$8
RVNC
28
DELISTED
Revance Therapeutics, Inc.
RVNC
$1.44M 0.08%
+88,590
New +$1.44M
CYTK icon
29
Cytokinetics
CYTK
$5.69B
$1.31M 0.07%
123,686
– –
ITCI
30
DELISTED
Intra-Cellular Therapies Inc.
ITCI
$1.28M 0.07%
+37,400
New +$1.28M
ALDX icon
31
Aldeyra Therapeutics
ALDX
$294M
$427K 0.02%
73,500
– –
VIRX
32
DELISTED
Viracta Therapeutics, Inc. Common Stock
VIRX
$393K 0.02%
33,214
– –
MRNS
33
DELISTED
Marinus Pharmaceuticals, Inc
MRNS
$271K 0.01%
31,330
– –
NERV icon
34
Minerva Neurosciences
NERV
$15M
$258K 0.01%
4,540
– –
ACGN
35
DELISTED
Aceragen, Inc. Common Stock
ACGN
$140K 0.01%
4,537
– –
SPHS
36
DELISTED
Sophiris Bio, Inc.
SPHS
$91K 0.01%
247,000
– –
MLNT
37
DELISTED
Melinta Therapeutics, Inc. Common Stock
MLNT
$5K ﹤0.01%
10,137
– –
ALDR
38
DELISTED
Alder Biopharmaceuticals, Inc.
ALDR
– –
-1,861,630
Closed -$35.1M
CELG
39
DELISTED
Celgene Corp
CELG
– –
-21,883
Closed -$2.17M
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