PAI

Palo Alto Investors Portfolio holdings

AUM $470M
1-Year Return 2.57%
This Quarter Return
+8.78%
1 Year Return
+2.57%
3 Year Return
+93.77%
5 Year Return
+190.64%
10 Year Return
+955.02%
AUM
$2.32B
AUM Growth
-$52.2M
Cap. Flow
-$40.4M
Cap. Flow %
-1.74%
Top 10 Hldgs %
73.45%
Holding
41
New
1
Increased
16
Reduced
7
Closed
4

Top Buys

1
IMMU
Immunomedics Inc
IMMU
+$28.5M
2
ALDR
Alder Biopharmaceuticals, Inc.
ALDR
+$20.3M
3
INSM icon
Insmed
INSM
+$7.26M
4
EPZM
Epizyme, Inc
EPZM
+$5.8M
5
BMRN icon
BioMarin Pharmaceuticals
BMRN
+$5.29M

Top Sells

1
ABMD
Abiomed Inc
ABMD
+$65.6M
2
UTHR icon
United Therapeutics
UTHR
+$23.1M
3
FOLD icon
Amicus Therapeutics
FOLD
+$20.4M
4
EXAS icon
Exact Sciences
EXAS
+$6.42M
5
AIMT
Aimmune Therapeutics, Inc.
AIMT
+$5.57M

Sector Composition

1 Healthcare 92.62%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
BIVV
26
DELISTED
Bioverativ Inc. Common Stock
BIVV
$14.3M 0.61%
264,400
+53,100
+25% +$2.86M
GILD icon
27
Gilead Sciences
GILD
$142B
$12.6M 0.54%
175,900
– –
DRNA
28
DELISTED
Dicerna Pharmaceuticals, Inc.
DRNA
$4.52M 0.19%
500,913
– –
VIRX
29
DELISTED
Viracta Therapeutics, Inc. Common Stock
VIRX
$4.29M 0.18%
33,214
– –
ALIM
30
DELISTED
Alimera Sciences, Inc.
ALIM
$4.01M 0.17%
200,920
– –
ACGN
31
DELISTED
Aceragen, Inc. Common Stock
ACGN
$1.3M 0.06%
4,537
– –
ZGNX
32
DELISTED
Zogenix, Inc.
ZGNX
$1.18M 0.05%
29,500
– –
CYTK icon
33
Cytokinetics
CYTK
$6.12B
$1.01M 0.04%
123,686
– –
MLNT
34
DELISTED
Melinta Therapeutics, Inc. Common Stock
MLNT
$801K 0.03%
+10,138
New +$801K
OCGN icon
35
Ocugen
OCGN
$334M
$621K 0.03%
5,049
– –
SPHS
36
DELISTED
Sophiris Bio, Inc.
SPHS
$561K 0.02%
247,000
– –
TRVN
37
DELISTED
Trevena, Inc.
TRVN
$546K 0.02%
546
– –
ARCT icon
38
Arcturus Therapeutics
ARCT
$470M
– –
-38,970
Closed -$276K
SLNO icon
39
Soleno Therapeutics
SLNO
$2.85B
– –
-1,130
Closed -$220K
TLPH icon
40
Talphera
TLPH
$19.3M
– –
-51,636
Closed -$4.75M
CEMP
41
DELISTED
Cempra, Inc.
CEMP
– –
-340,320
Closed -$1.11M
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