PAI

Palo Alto Investors Portfolio holdings

AUM $470M
1-Year Return 2.57%
This Quarter Return
+10.42%
1 Year Return
+2.57%
3 Year Return
+93.77%
5 Year Return
+190.64%
10 Year Return
+955.02%
AUM
$2.14B
AUM Growth
+$26.3M
Cap. Flow
-$121M
Cap. Flow %
-5.64%
Top 10 Hldgs %
74.41%
Holding
40
New
1
Increased
15
Reduced
4
Closed
2

Top Buys

1
IMMU
Immunomedics Inc
IMMU
+$26.6M
2
EPZM
Epizyme, Inc
EPZM
+$13.7M
3
ABMD
Abiomed Inc
ABMD
+$4.27M
4
AIMT
Aimmune Therapeutics, Inc.
AIMT
+$2.39M
5
INSM icon
Insmed
INSM
+$1.5M

Top Sells

1
ZLTQ
ZELTIQ Aesthetics, Inc.
ZLTQ
+$113M
2
CLVS
Clovis Oncology, Inc.
CLVS
+$52.9M
3
SAGE
Sage Therapeutics
SAGE
+$5.49M
4
UTHR icon
United Therapeutics
UTHR
+$2.08M
5
RIGL icon
Rigel Pharmaceuticals
RIGL
+$1.09M

Sector Composition

1 Healthcare 94.57%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
ALIM
26
DELISTED
Alimera Sciences, Inc.
ALIM
$4.19M 0.2%
200,920
– –
VIRX
27
DELISTED
Viracta Therapeutics, Inc. Common Stock
VIRX
$3.14M 0.15%
33,214
– –
TLPH icon
28
Talphera
TLPH
$20.1M
$2.22M 0.1%
51,636
– –
DRNA
29
DELISTED
Dicerna Pharmaceuticals, Inc.
DRNA
$1.59M 0.07%
500,913
+19,394
+4% +$61.5K
CEMP
30
DELISTED
Cempra, Inc.
CEMP
$1.57M 0.07%
340,320
– –
CYTK icon
31
Cytokinetics
CYTK
$5.95B
$1.5M 0.07%
123,686
– –
ACGN
32
DELISTED
Aceragen, Inc. Common Stock
ACGN
$1.06M 0.05%
4,537
– –
TRVN
33
DELISTED
Trevena, Inc.
TRVN
$785K 0.04%
546
– –
SPHS
34
DELISTED
Sophiris Bio, Inc.
SPHS
$543K 0.03%
247,000
– –
OCGN icon
35
Ocugen
OCGN
$365M
$542K 0.03%
5,049
– –
ZGNX
36
DELISTED
Zogenix, Inc.
ZGNX
$428K 0.02%
29,500
– –
ARCT icon
37
Arcturus Therapeutics
ARCT
$492M
$306K 0.01%
38,970
– –
SLNO icon
38
Soleno Therapeutics
SLNO
$2.72B
$212K 0.01%
5,650
– –
PGEN icon
39
Precigen
PGEN
$1.16B
– –
-41,900
Closed -$830K
ZLTQ
40
DELISTED
ZELTIQ Aesthetics, Inc.
ZLTQ
– –
-2,032,692
Closed -$113M
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