We are live on ! Find out more
PAI

Palo Alto Investors Portfolio holdings

AUM $654M
1-Year Est. Return 77.8%
This Fund
S&P 500
This Quarter Est. Return
+35.14%
1 Year Est. Return
+77.8%
3 Year Est. Return
+127.05%
5 Year Est. Return
+199.24%
10 Year Est. Return
+2,229.57%
AUM
$2.02B
AUM Growth
+$319M
Cap. Flow
-$99.3M
Cap. Flow %
-4.91%
Top 10 Hldgs %
71.4%
Holding
52
New
6
Increased
25
Reduced
3
Closed
6

Top Buys

Rank Stock Value
1
THOR
THORATEC CORPORATION
THOR
+$86.6M
2
ENDP
Endo International plc
ENDP
+$71.9M
3
BMRN icon
BioMarin Pharmaceuticals
BMRN
+$36.8M
4
ANAC
ANACOR PHARMACEUTICALS INC COM
ANAC
+$31.3M
5
KPTI icon
Karyopharm Therapeutics
KPTI
+$27.3M

Top Sells

Rank Stock Value
1
AUXL
AUXILIUM PHARAMCEUTICALS INC
AUXL
+$169M
2
CBST
CUBIST PHARMACEUTICALS INC
CBST
+$131M
3
CYBX
CYBERONICS INC
CYBX
+$72.8M
4
NPSP
NPS PHARMACEUTICALS INC
NPSP
+$42.6M
5
SLXP
SALIX PHARMACEUTICALS LTD DEL
SLXP
+$10.5M

Sector Composition

Rank Sector Weight
1 Healthcare 70.55%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
RIGL icon
26
Rigel Pharmaceuticals
RIGL
$782M
$18.5M 0.91%
517,632
– –
ARIA
27
DELISTED
Ariad Pharmaceuticals Inc
ARIA
$18.4M 0.91%
2,231,717
– –
ZLTQ
28
DELISTED
ZELTIQ Aesthetics, Inc.
ZLTQ
$17.5M 0.87%
568,436
+173,950
+44% +$5.56M
ISRG icon
29
Intuitive Surgical
ISRG
$142B
$16.3M 0.81%
291,150
+56,700
+24% +$3.21M
ALGN icon
30
Align Technology
ALGN
$12.4B
$15.2M 0.75%
282,057
+47,757
+20% +$2.72M
OREX
31
DELISTED
Orexigen Therapeutics, Inc.
OREX
$15.1M 0.75%
193,132
– –
ALIM
32
DELISTED
Alimera Sciences
ALIM
$15.1M 0.75%
200,920
– –
EXAS
33
DELISTED
Exact Sciences
EXAS
$8.65M 0.43%
392,676
+1,400
+0.4% +$35.5K
TLPH icon
34
Talphera
TLPH
$72.7M
$8.24M 0.41%
106,787
+360
+0.3% +$47.1K
OCGN icon
35
Ocugen
OCGN
$475M
$4.54M 0.22%
7,576
– –
ACGN
36
DELISTED
Aceragen Inc
ACGN
$4.34M 0.21%
+8,613
New +$5.25M
XOMA
37
DELISTED
Xoma
XOMA
$2.89M 0.14%
39,725
– –
PGEN icon
38
Precigen
PGEN
$2.45B
$2.14M 0.11%
49,282
+3,557
+8% +$128K
BSTC
39
DELISTED
BioSpecifics Technologies Corp.
BSTC
$1.98M 0.1%
50,436
– –
VIRX
40
DELISTED
Viracta Therapeutics, Inc. Common Stock
VIRX
$1.48M 0.07%
+2,873
New +$1.45M
QLTI
41
DELISTED
QLT Inc
QLTI
$1.24M 0.06%
315,906
-1,417,302
-82% -$5.84M
SLXP
42
DELISTED
SALIX PHARMACEUTICALS LTD DEL
SLXP
$916K 0.05%
5,300
-71,400
-93% -$10.5M
CYTK icon
43
Cytokinetics
CYTK
$10.5B
$839K 0.04%
123,686
– –
MNK
44
DELISTED
MALLINCKRODT PUBLIC LIMITED COMPANY
MNK
$454K 0.02%
3,588
– –
ARCT icon
45
Arcturus Therapeutics
ARCT
$216M
$412K 0.02%
+10,455
New +$460K
SPHS
46
DELISTED
Sophiris Bio, Inc.
SPHS
$111K 0.01%
191,600
– –
AVEO
47
DELISTED
AVEO Pharmaceuticals, Inc.
AVEO
– –
-66,945
Closed -$562K
NXTM
48
DELISTED
NxStage Medical Inc.
NXTM
– –
-20,200
Closed -$362K
HPTX
49
DELISTED
HYPERION THERAPEUTICS INC COM STK (DE)
HPTX
– –
-62,700
Closed -$1.5M
NPSP
50
DELISTED
NPS PHARMACEUTICALS INC
NPSP
– –
-1,190,263
Closed -$42.6M
1
2
3

Similar funds

AG
Alibaba Group Causeway Bay, Hong Kong $653M AUM 16.11% 1-Year Est. Return
BL
BWCP LP Dallas, Texas $656M AUM 41.58% 1-Year Est. Return
PIM
Parker Investment Management Menlo Park, California $659M AUM 52.52% 1-Year Est. Return
ACA
Apis Capital Advisors New York $648M AUM 302.67% 1-Year Est. Return
PCM
Primavera Capital Management George Town, Cayman Islands $648M AUM 6.1% 1-Year Est. Return
HCM
Huber Capital Management El Segundo, California $647M AUM 24.91% 1-Year Est. Return
ACM
Arosa Capital Management Miami Beach, Florida $660M AUM 210.26% 1-Year Est. Return
DC
Decheng Capital Menlo Park, California $661M AUM 299.97% 1-Year Est. Return

Palo Alto Investors's Q1 2015 Portfolio in Review

As of Q1 2015, Palo Alto Investors held 52 positions worth $2.02B, up 19% from $1.7B the previous quarter. Its ten largest holdings account for 71% of the portfolio.

Palo Alto Investors withdrew a net $99.3M in Q1 2015, closing 6 positions and reducing 3 holdings. Its most notable exit was AUXILIUM PHARAMCEUTICALS INC, an estimated $169M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 71% of assets, up from 58% a quarter earlier.

Against the trend, Palo Alto Investors opened a new position in Endo International plc worth $77.2M.

  • Palo Alto Investors's largest Q1 2015 buy was Endo International plc: 860,204 shares worth $77.2M.
  • Palo Alto Investors added most to THORATEC CORPORATION in Q1 2015, an estimated $86.6M increase.
  • Palo Alto Investors's biggest Q1 2015 reduction was CYBERONICS INC, cutting an estimated $72.8M.
  • Palo Alto Investors fully exited AUXILIUM PHARAMCEUTICALS INC in Q1 2015, selling an estimated $169M.
  • Palo Alto Investors's ten largest holdings make up 71% of its $2.02B portfolio in Q1 2015.
  • Palo Alto Investors opened 6 new positions and closed 6 in Q1 2015.
  • Palo Alto Investors's portfolio value rose 19% quarter-over-quarter to $2.02B.

Based on Palo Alto Investors's 13F filing for Q1 2015, filed 15 May 2015.