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PAI

Palo Alto Investors Portfolio holdings

AUM $654M
1-Year Est. Return 77.8%
This Fund
S&P 500
This Quarter Est. Return
+4.77%
1 Year Est. Return
+77.8%
3 Year Est. Return
+127.05%
5 Year Est. Return
+199.24%
10 Year Est. Return
+2,229.57%
AUM
$1.34B
AUM Growth
+$133M
Cap. Flow
+$113M
Cap. Flow %
8.44%
Top 10 Hldgs %
66.4%
Holding
43
New
4
Increased
25
Reduced
6
Closed
1

Top Buys

Rank Stock Value
1
CLVS
Clovis Oncology, Inc.
CLVS
+$37.5M
2
ITMN
INTERMUNE INC
ITMN
+$26.3M
3
GILD icon
Gilead Sciences
GILD
+$11.7M
4
AGN
Allergan Inc
AGN
+$11.5M
5
CELG
Celgene Corp
CELG
+$11.4M

Top Sells

Rank Stock Value
1
QCOR
QUESTCOR PHARMA INC
QCOR
+$64.3M
2
ARIA
Ariad Pharmaceuticals Inc
ARIA
+$8.14M
3
SPPI
Spectrum Pharmaceuticals Inc
SPPI
+$3.15M
4
QLTI
QLT Inc
QLTI
+$852K
5
CYTK icon
Cytokinetics
CYTK
+$754K

Sector Composition

Rank Sector Weight
1 Healthcare 45.02%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
EXAS
26
DELISTED
Exact Sciences
EXAS
$13.2M 0.99%
777,676
– –
GILD icon
27
Gilead Sciences
GILD
$168B
$12.8M 0.95%
154,400
+150,800
+4,189% +$11.7M
AGN
28
DELISTED
Allergan Inc
AGN
$12.5M 0.93%
+73,900
New +$11.5M
PRTA icon
29
Prothena Corp
PRTA
$475M
$12M 0.9%
534,018
+1,100
+0.2% +$27.5K
OREX
30
DELISTED
Orexigen Therapeutics, Inc.
OREX
$11.9M 0.89%
193,132
+26,230
+16% +$1.53M
QLTI
31
DELISTED
QLT Inc
QLTI
$11.7M 0.87%
1,887,208
-153,835
-8% -$852K
ALGN icon
32
Align Technology
ALGN
$12.4B
$9.91M 0.74%
176,788
+169,000
+2,170% +$8.79M
MDVN
33
DELISTED
MEDIVATION, INC.
MDVN
$9.47M 0.71%
+245,800
New +$8.29M
ISRG icon
34
Intuitive Surgical
ISRG
$142B
$7.58M 0.56%
+165,600
New +$7.31M
GERN icon
35
Geron
GERN
$1.01B
$4.04M 0.3%
1,332,551
+795,828
+148% +$1.66M
RVNC
36
DELISTED
Revance Therapeutics, Inc.
RVNC
$3.12M 0.23%
91,669
– –
XOMA
37
DELISTED
Xoma
XOMA
$2.87M 0.21%
31,245
+18,440
+144% +$1.6M
AVEO
38
DELISTED
AVEO Pharmaceuticals, Inc.
AVEO
$2.2M 0.16%
120,080
-22,837
-16% -$297K
HPTX
39
DELISTED
HYPERION THERAPEUTICS INC COM STK (DE)
HPTX
$1.64M 0.12%
62,700
– –
SPHS
40
DELISTED
Sophiris Bio, Inc.
SPHS
$656K 0.05%
292,900
– –
CYTK icon
41
Cytokinetics
CYTK
$10.5B
$591K 0.04%
123,686
-123,500
-50% -$754K
BSTC
42
DELISTED
BioSpecifics Technologies Corp.
BSTC
$302K 0.02%
+11,184
New +$291K
SPPI
43
DELISTED
Spectrum Pharmaceuticals Inc
SPPI
– –
-402,285
Closed -$3.15M
1
2

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Palo Alto Investors's Q2 2014 Portfolio in Review

As of Q2 2014, Palo Alto Investors held 43 positions worth $1.34B, up 11% from $1.21B the previous quarter. Its ten largest holdings account for 66% of the portfolio.

Palo Alto Investors deployed $113M of net new capital in Q2 2014, opening 4 new positions and adding to 25 existing holdings. Its largest new stake was Allergan Inc: 73,900 shares worth $12.5M.

By sector, the portfolio is most concentrated in Healthcare at 45% of assets, up from 42% a quarter earlier.

On the sell side, the largest reduction was QUESTCOR PHARMA INC, an estimated $64.3M trimmed.

  • Palo Alto Investors's largest Q2 2014 buy was Allergan Inc: 73,900 shares worth $12.5M.
  • Palo Alto Investors added most to Clovis Oncology, Inc. in Q2 2014, an estimated $37.5M increase.
  • Palo Alto Investors's biggest Q2 2014 reduction was QUESTCOR PHARMA INC, cutting an estimated $64.3M.
  • Palo Alto Investors fully exited Spectrum Pharmaceuticals Inc in Q2 2014, selling an estimated $3.15M.
  • Palo Alto Investors's ten largest holdings make up 66% of its $1.34B portfolio in Q2 2014.
  • Palo Alto Investors opened 4 new positions and closed 1 in Q2 2014.
  • Palo Alto Investors's portfolio value rose 11% quarter-over-quarter to $1.34B.

Based on Palo Alto Investors's 13F filing for Q2 2014, filed 14 Aug 2014.