O

OrbiMed Portfolio holdings

AUM $3.98B
This Quarter Return
-5.92%
1 Year Return
+13.05%
3 Year Return
+159.74%
5 Year Return
+207.27%
10 Year Return
+1,027.33%
AUM
$4.16B
AUM Growth
+$4.16B
Cap. Flow
-$176M
Cap. Flow %
-4.24%
Top 10 Hldgs %
48.04%
Holding
122
New
11
Increased
15
Reduced
22
Closed
16

Top Buys

1
PFE icon
Pfizer
PFE
$97.6M
2
AXSM icon
Axsome Therapeutics
AXSM
$45.1M
3
SION
Sionna Therapeutics, Inc. Common Stock
SION
$38.8M
4
UNH icon
UnitedHealth
UNH
$36.8M
5
TARS icon
Tarsus Pharmaceuticals
TARS
$33.6M

Top Sells

1
SRPT icon
Sarepta Therapeutics
SRPT
$117M
2
MRK icon
Merck
MRK
$82.6M
3
BIIB icon
Biogen
BIIB
$77.9M
4
ISRG icon
Intuitive Surgical
ISRG
$54.8M
5
UHS icon
Universal Health Services
UHS
$48.3M

Sector Composition

1 Healthcare 99.7%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
SIBN icon
26
SI-BONE Inc
SIBN
$700M
$48.3M 1.15%
3,442,853
– –
AXSM icon
27
Axsome Therapeutics
AXSM
$6.09B
$45.1M 1.08%
+386,700
New +$45.1M
CMPX icon
28
Compass Therapeutics
CMPX
$466M
$42.5M 1.01%
22,362,850
– –
SWTX
29
DELISTED
SpringWorks Therapeutics
SWTX
$41.9M 1%
950,200
-304,831
-24% -$13.5M
NPCE icon
30
Neuropace
NPCE
$310M
$41.9M 1%
3,406,335
– –
SION
31
Sionna Therapeutics, Inc. Common Stock
SION
$1.08B
$38.8M 0.92%
+3,704,959
New +$38.8M
UPB
32
Upstream Bio, Inc. Common Stock
UPB
$1.08B
$34.8M 0.83%
5,693,589
– –
XTNT icon
33
Xtant Medical Holdings
XTNT
$82.4M
$34.4M 0.82%
73,114,592
– –
TARS icon
34
Tarsus Pharmaceuticals
TARS
$2.44B
$33.6M 0.8%
+653,743
New +$33.6M
CRNX icon
35
Crinetics Pharmaceuticals
CRNX
$3.26B
$33.5M 0.8%
999,000
– –
XENE icon
36
Xenon Pharmaceuticals
XENE
$2.99B
$31.8M 0.76%
947,877
– –
APLS icon
37
Apellis Pharmaceuticals
APLS
$3.51B
$31.3M 0.75%
+1,432,300
New +$31.3M
MBX
38
MBX Biosciences, Inc. Common Stock
MBX
$484M
$29.5M 0.7%
4,002,887
+190,672
+5% +$1.41M
EXAS icon
39
Exact Sciences
EXAS
$9.33B
$29.4M 0.7%
679,816
– –
GILD icon
40
Gilead Sciences
GILD
$140B
$22.1M 0.53%
197,500
-48,100
-20% -$5.39M
CRVS icon
41
Corvus Pharmaceuticals
CRVS
$419M
$22.1M 0.53%
6,943,654
– –
TERN icon
42
Terns Pharmaceuticals
TERN
$651M
$20.9M 0.5%
7,562,971
– –
JANX icon
43
Janux Therapeutics
JANX
$1.38B
$20.5M 0.49%
758,566
– –
RYTM icon
44
Rhythm Pharmaceuticals
RYTM
$6.75B
$20.1M 0.48%
380,000
-20,000
-5% -$1.06M
THRD
45
DELISTED
Third Harmonic Bio
THRD
$20.1M 0.48%
5,779,071
– –
FOLD icon
46
Amicus Therapeutics
FOLD
$2.42B
$18.6M 0.44%
2,285,400
– –
VSTM icon
47
Verastem
VSTM
$585M
$17.3M 0.41%
2,862,448
– –
TYRA icon
48
Tyra Biosciences
TYRA
$657M
$16.3M 0.39%
1,752,831
+282,745
+19% +$2.63M
RAPT icon
49
RAPT Therapeutics
RAPT
$187M
$16M 0.38%
1,641,908
– –
SCPH icon
50
scPharmaceuticals
SCPH
$296M
$15.9M 0.38%
6,059,528
– –
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