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Opaleye Management Portfolio holdings

AUM $758M
1-Year Est. Return 124.8%
This Fund
S&P 500
This Quarter Est. Return
+16.07%
1 Year Est. Return
+124.8%
3 Year Est. Return
+486.05%
5 Year Est. Return
+742.19%
10 Year Est. Return
+62,231.09%
AUM
$758M
AUM Growth
+$50.6M
Cap. Flow
+$32.3M
Cap. Flow %
4.26%
Top 10 Hldgs %
65.47%
Holding
64
New
21
Increased
16
Reduced
8
Closed
9

Top Buys

1
RZLT icon
Rezolute
RZLT
+$42.2M
2
CBIO
Crescent Biopharma
CBIO
+$15M
3
ACOG
Alpha Cognition
ACOG
+$12.4M
4
SLGL icon
Sol-Gel Technologies
SLGL
+$9.61M
5
URGN icon
UroGen Pharma
URGN
+$5.82M

Top Sells

1
IMNM icon
Immunome
IMNM
+$37.3M
2
RYTM icon
Rhythm Pharmaceuticals
RYTM
+$14M
3
CDXS icon
Codexis
CDXS
+$12.2M
4
SRPT icon
Sarepta Therapeutics
SRPT
+$11.3M
5
LRMR icon
Larimar Therapeutics
LRMR
+$10.6M

Sector Composition

1 Healthcare 100%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
AVIR icon
51
Atea Pharmaceuticals
AVIR
$376M
$642K 0.08%
+179,815
New +$571K
SLN
52
Silence Therapeutics
SLN
$461M
$480K 0.06%
+78,926
New +$505K
RAPT
53
DELISTED
RAPT Therapeutics
RAPT
$213K 0.03%
+150,000
New +$4.66M
ADGM
54
Adagio Medical Holdings
ADGM
$12.9M
$19.2K ﹤0.01%
18,444
-92,127
-83% -$109K
ADCT icon
55
ADC Therapeutics
ADCT
$156M
– –
-682,529
Closed -$2.73M
ARVN icon
56
Arvinas
ARVN
$534M
– –
-987,818
Closed -$8.42M
IBIO icon
57
iBio
IBIO
$71.5M
– –
-375,000
Closed -$310K
IMNM icon
58
Immunome
IMNM
$2.56B
– –
-3,185,000
Closed -$37.3M
LRMR icon
59
Larimar Therapeutics
LRMR
$386M
– –
-3,720,867
Closed -$10.6M
PEPG icon
60
PepGen
PEPG
$169M
– –
-75,000
Closed -$347K
SRPT icon
61
Sarepta Therapeutics
SRPT
$1.9B
– –
-585,000
Closed -$11.3M
SYRE icon
62
Spyre Therapeutics
SYRE
$8.59B
– –
-65,000
Closed -$1.09M
TMCI icon
63
Treace Medical Concepts
TMCI
$288M
– –
-702,245
Closed -$4.71M
1 2
3

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