Nisa Investment Advisors
UPB

Nisa Investment Advisors’s Upstream Bio Inc UPB Stock Holding History

Nisa Investment Advisors’s Portfolio UPB Stock Details UPB Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$29.6K Sell
4,278
-15,280
-78% -$128K ﹤0.01% 2062
2026
Q1 		$176K Buy
19,558
+19,158
+4,790% +$345K ﹤0.01% 1254
2025
Q4 		$10.9K Buy
400
+304
+317% +$7.57K ﹤0.01% 2178
2025
Q3 		$1.81K Hold
96
– – ﹤0.01% 2643
2025
Q2 		$1.05K Sell
96
-40
-29% -$369 ﹤0.01% 2727
2025
Q1 		$832 Buy
+136
New +$1.3K ﹤0.01% 2685

Other funds holding UPB

BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
SAM
SEB Asset Management Stockholm $26.6B AUM
State Street
State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return
YIH
Y-Intercept (HK) Hong Kong $5.05B AUM 17.89% 1-Year Est. Return
Walleye Capital
Walleye Capital New York $28B AUM 44.22% 1-Year Est. Return
Deutsche Bank
Deutsche Bank Frankfurt Am Main Ge, Germany $344B AUM 42.99% 1-Year Est. Return
Bank of New York Mellon
Bank of New York Mellon New York $609B AUM 40.19% 1-Year Est. Return
GCP
GSA Capital Partners London, United Kingdom $1.59B AUM 39.81% 1-Year Est. Return
SAM
Simplify Asset Management Las Vegas, Nevada $7.19B AUM 6.88% 1-Year Est. Return
AA
ALPS Advisors Denver, Colorado $21.3B AUM 23.41% 1-Year Est. Return

Nisa Investment Advisors's UPB Position: Q2 2026 in Review

Nisa Investment Advisors reduced its Upstream Bio Inc (UPB) stake by 78% in Q2 2026, selling an estimated $128K and leaving 4,278 shares worth $29.6K. The position accounts for ﹤0.01% of the portfolio, ranked #2062.

Nisa Investment Advisors first reported a position in UPB in Q1 2025 and has held it in 6 quarters since. The position peaked at $176K in Q1 2026. 42 funds tracked by Wall St. Rank hold UPB as of Q2 2026.

  • Nisa Investment Advisors held 4,278 shares of Upstream Bio Inc worth $29.6K as of Q2 2026.
  • Nisa Investment Advisors sold 15,280 Upstream Bio Inc shares in Q2 2026, an estimated $128K.
  • Upstream Bio Inc made up ﹤0.01% of Nisa Investment Advisors's portfolio in Q2 2026, its #2062 holding.
  • Nisa Investment Advisors first reported a position in Upstream Bio Inc in Q1 2025 and has held it in 6 quarters since.
  • Nisa Investment Advisors's Upstream Bio Inc position peaked at $176K in Q1 2026.
  • 42 funds tracked by Wall St. Rank held Upstream Bio Inc as of Q2 2026.

Based on Nisa Investment Advisors's 13F filing for Q2 2026, filed 10 Aug 2026.