LCM
UPB

Lynx1 Capital Management’s Upstream Bio Inc UPB Stock Holding History

Lynx1 Capital Management’s Portfolio UPB Stock Details UPB Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q3 		– Sell
-219,247
Closed -$2.41M – 16
2025
Q2 		$2.41M Hold
219,247
– – 0.7% 11
2025
Q1 		$1.34M Sell
219,247
-20,795
-9% -$199K 0.48% 12
2024
Q4 		$3.95M Buy
+240,042
New +$5.36M 1.48% 11

Other funds holding UPB

Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
O
OrbiMed New York $5.05B AUM 125.28% 1-Year Est. Return
DC
Decheng Capital Menlo Park, California $661M AUM 299.97% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
ES
Enavate Sciences Menlo Park, California $352M AUM 220.14% 1-Year Est. Return
Vanguard Group
Vanguard Group Malvern, Pennsylvania $6.9T AUM 27.45% 1-Year Est. Return
BCLSI
Bain Capital Life Sciences Investors Boston, Massachusetts $1.11B AUM 171.34% 1-Year Est. Return
TCM
TCG Crossover Management Palo Alto, California $3.5B AUM 1,165.83% 1-Year Est. Return
AS
Altshuler Shaham Tel Aviv, Israel $5.54B AUM 44.68% 1-Year Est. Return
OFM
Omega Fund Management Boston, Massachusetts $163M AUM 107.06% 1-Year Est. Return

Lynx1 Capital Management's UPB Position: Q3 2025 in Review

Lynx1 Capital Management sold out of Upstream Bio Inc (UPB) in Q3 2025, closing a stake of 219,247 shares — an estimated $2.41M sold.

Lynx1 Capital Management first reported a position in UPB in Q4 2024 and held it in 3 quarters. The position peaked at $3.95M in Q4 2024. 95 funds tracked by Wall St. Rank hold UPB as of Q3 2025.

  • Lynx1 Capital Management reported no remaining Upstream Bio Inc position as of Q3 2025 after selling out during the quarter.
  • Lynx1 Capital Management sold 219,247 Upstream Bio Inc shares in Q3 2025, an estimated $2.41M.
  • Lynx1 Capital Management first reported a position in Upstream Bio Inc in Q4 2024 and held it in 3 quarters.
  • Lynx1 Capital Management's Upstream Bio Inc position peaked at $3.95M in Q4 2024.
  • 95 funds tracked by Wall St. Rank held Upstream Bio Inc as of Q3 2025.

Based on Lynx1 Capital Management's 13F filing for Q3 2025, filed 13 Nov 2025.