Jim Simons’s Lexicon Pharmaceuticals LXRX Stock Holding History

Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake
Trade Value Portfolio Weight Portfolio Position
2026
Q1
$2.5M Buy
1,600,500
+1,337,246
+508% +$1.94M ﹤0.01% 1773
2025
Q4
$303K Sell
263,254
-29,146
-10% -$40K ﹤0.01% 2757
2025
Q3
$395K Buy
+292,400
New +$332K ﹤0.01% 2890
2025
Q1
Sell
-51,141
Closed -$37.8K 3687
2024
Q4
$37.8K Buy
+51,141
New +$61.6K ﹤0.01% 3422
2024
Q1
Sell
-412,175
Closed -$631K 3919
2023
Q4
$631K Buy
412,175
+139,920
+51% +$166K ﹤0.01% 2676
2023
Q3
$297K Buy
+272,255
New +$478K ﹤0.01% 2935
2023
Q2
Sell
-263,875
Closed -$641K 4119
2023
Q1
$641K Sell
263,875
-129,410
-33% -$297K ﹤0.01% 2746
2022
Q4
$751K Sell
393,285
-88,090
-18% -$187K ﹤0.01% 2699
2022
Q3
$1.16M Buy
+481,375
New +$1.33M ﹤0.01% 2404
2022
Q2
Sell
-88,776
Closed -$186K 4436
2022
Q1
$186K Buy
+88,776
New +$246K ﹤0.01% 3668
2021
Q3
Sell
-59,775
Closed -$274K 3687
2021
Q2
$274K Sell
59,775
-252,704
-81% -$1.22M ﹤0.01% 3174
2021
Q1
$1.83M Sell
312,479
-682,500
-69% -$4.73M ﹤0.01% 2285
2020
Q4
$3.4M Sell
994,979
-637,652
-39% -$1.22M ﹤0.01% 1823
2020
Q3
$2.35M Sell
1,632,631
-247,572
-13% -$441K ﹤0.01% 2042
2020
Q2
$3.75M Buy
1,880,203
+213,605
+13% +$419K ﹤0.01% 1819
2020
Q1
$3.25M Buy
1,666,598
+463,420
+39% +$1.38M ﹤0.01% 1805
2019
Q4
$4.99M Buy
1,203,178
+537,799
+81% +$2.07M ﹤0.01% 1854
2019
Q3
$2M Buy
665,379
+118,638
+22% +$367K ﹤0.01% 2285
2019
Q2
$3.44M Buy
546,741
+57,228
+12% +$343K ﹤0.01% 2041
2019
Q1
$2.72M Buy
489,513
+145,027
+42% +$881K ﹤0.01% 2152
2018
Q4
$2.29M Buy
344,486
+252,900
+276% +$2.05M ﹤0.01% 2162
2018
Q3
$977K Sell
91,586
-100,840
-52% -$1.16M ﹤0.01% 2612
2018
Q2
$2.31M Sell
192,426
-36,660
-16% -$375K ﹤0.01% 2196
2018
Q1
$1.96M Sell
229,086
-275,800
-55% -$2.55M ﹤0.01% 2337
2017
Q4
$4.99M Buy
504,886
+216,800
+75% +$2.25M 0.01% 1806
2017
Q3
$3.54M Sell
288,086
-96,011
-25% -$1.42M ﹤0.01% 1967
2017
Q2
$6.32M Buy
384,097
+122,592
+47% +$1.9M 0.01% 1562
2017
Q1
$3.75M Buy
+261,505
New +$3.88M 0.01% 1870
2015
Q4
Sell
-11,086
Closed -$119K 3361
2015
Q3
$119K Sell
11,086
-159,067
-93% -$1.74M ﹤0.01% 2984
2015
Q2
$1.37M Sell
170,153
-63,580
-27% -$467K ﹤0.01% 2291
2015
Q1
$1.54M Buy
233,733
+134,317
+135% +$917K ﹤0.01% 2071
2014
Q4
$633K Buy
+99,416
New +$801K ﹤0.01% 2350
2014
Q1
Sell
-35,192
Closed -$443K 2937
2013
Q4
$443K Buy
+35,192
New +$560K ﹤0.01% 2391

Other funds holding LXRX

Jim Simons's LXRX Position: Q1 2026 in Review

Jim Simons increased its Lexicon Pharmaceuticals (LXRX) stake by 508% in Q1 2026, buying an estimated $1.94M and bringing the position to 1,600,500 shares worth $2.5M. The position accounts for ﹤0.01% of the portfolio, ranked #1773.

Jim Simons first reported a position in LXRX in Q4 2013 and has held it in 33 quarters since. The position peaked at $6.32M in Q2 2017. 136 funds tracked by Wall St. Rank hold LXRX as of Q1 2026.

  • Jim Simons held 1,600,500 shares of Lexicon Pharmaceuticals worth $2.5M as of Q1 2026.
  • Jim Simons bought 1,337,246 Lexicon Pharmaceuticals shares in Q1 2026, an estimated $1.94M.
  • Lexicon Pharmaceuticals made up ﹤0.01% of Jim Simons's portfolio in Q1 2026, its #1773 holding.
  • Jim Simons first reported a position in Lexicon Pharmaceuticals in Q4 2013 and has held it in 33 quarters since.
  • Jim Simons's Lexicon Pharmaceuticals position peaked at $6.32M in Q2 2017.
  • 136 funds tracked by Wall St. Rank held Lexicon Pharmaceuticals as of Q1 2026.

Based on Renaissance Technologies's 13F filing for Q1 2026, filed 14 May 2026.