Jane Street’s Omeros OMER Stock Holding History

Jane Street’s Portfolio OMER Stock Details OMER Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q1	$887K	Sell	84,000 -87,100	-51%	-$1.03M	﹤0.01%	6779
2025 Q4	$2.94M	Buy	171,100 +133,300	+353%	+$1.15M	﹤0.01%	4079
2025 Q3	$155K	Buy	+37,800	New	+$150K	﹤0.01%	9862
2025 Q2	–	Sell	-78,000	Closed	-$641K	–	10502
2025 Q1	$641K	Buy	78,000 +10,700	+16%	+$94.5K	﹤0.01%	6404
2024 Q4	$665K	Buy	+67,300	New	+$462K	﹤0.01%	6161
2022 Q2	–	Sell	-21,000	Closed	-$126K	–	10509
2022 Q1	$126K	Sell	21,000 -136,000	-87%	-$848K	﹤0.01%	9338
2021 Q4	$1.01M	Sell	157,000 -21,000	-12%	-$152K	﹤0.01%	5868
2021 Q3	$2.46M	Buy	178,000 +12,000	+7%	+$180K	﹤0.01%	4054
2021 Q2	$2.46M	Buy	166,000 +112,000	+207%	+$1.88M	﹤0.01%	3928
2021 Q1	$961K	Sell	54,000 -40,000	-43%	-$778K	﹤0.01%	5527
2020 Q4	$1.34M	Sell	94,000 -14,700	-14%	-$180K	﹤0.01%	4188
2020 Q3	$1.1M	Buy	108,700 +96,100	+763%	+$1.24M	﹤0.01%	3945
2020 Q2	$185K	Hold	12,600	–	–	﹤0.01%	6418
2020 Q1	$168K	Buy	+12,600	New	+$168K	﹤0.01%	4726
2018 Q2	–	Sell	-21,800	Closed	-$244K	–	5426
2018 Q1	$244K	Buy	21,800 +5,900	+37%	+$82.8K	﹤0.01%	4252
2017 Q4	$309K	Buy	+15,900	New	+$298K	﹤0.01%	3730
2017 Q3	–	Sell	-21,900	Closed	-$436K	–	4888
2017 Q2	$436K	Buy	+21,900	New	+$382K	﹤0.01%	3201

Other funds holding OMER

BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return

ISL

Ingalls & Snyder LLC New York $2.83B AUM 21.61% 1-Year Est. Return

VCM

Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM

UBS Group Zurich, Switzerland $666B AUM 30.12% 1-Year Est. Return

State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return

Stifel Financial St. Louis, Missouri $109B AUM 21.36% 1-Year Est. Return

Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return

Corient Private Wealth Miami, Florida $69.9B AUM 22.19% 1-Year Est. Return

VPM

Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM

Charles Schwab San Francisco, California $654B AUM 26.35% 1-Year Est. Return

Jane Street's OMER Position: Q1 2026 in Review

Jane Street reduced its Omeros (OMER) stake by 69% in Q1 2026, selling an estimated $3.75M and leaving 145,307 shares worth $1.53M. The position accounts for ﹤0.01% of the portfolio, ranked #5594.

Jane Street first reported a position in OMER in Q4 2013 and has held it in 29 quarters since. The position peaked at $7.96M in Q4 2025. 161 funds tracked by Wall St. Rank hold OMER as of Q1 2026.

Jane Street held 145,307 shares of Omeros worth $1.53M as of Q1 2026.
Jane Street sold 318,315 Omeros shares in Q1 2026, an estimated $3.75M.
Omeros made up ﹤0.01% of Jane Street's portfolio in Q1 2026, its #5594 holding.
Jane Street first reported a position in Omeros in Q4 2013 and has held it in 29 quarters since.
Jane Street's Omeros position peaked at $7.96M in Q4 2025.
161 funds tracked by Wall St. Rank held Omeros as of Q1 2026.

Based on Jane Street's 13F filing for Q1 2026, filed 12 May 2026.