Omeros
OMER
137 hedge funds and large institutions have $227M invested in Omeros in 2025 Q1 according to their latest regulatory filings, with 21 funds opening new positions, 35 increasing their positions, 51 reducing their positions, and 12 closing their positions.
75% more first-time investments, than exits
New positions opened: 21 | Existing positions closed: 12
7% more funds holding
Funds holding: 128 → 137 (+9)
1.76% more ownership
Funds ownership: 45.83% → 47.59% (+1.8%)
14% less capital invested
Capital invested by funds: $262M → $227M (-$35.6M)
31% less repeat investments, than reductions
Existing positions increased: 35 | Existing positions reduced: 51
35% less call options, than puts
Call options by funds: $4.15M | Put options by funds: $6.34M
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Marshall Wace
London,
United Kingdom
|
+$5.3M |
| 2 |
Morgan Stanley
New York
|
+$3.76M |
| 3 |
Millennium Management
New York
|
+$2.03M |
| 4 |
Osaic Holdings
Scottsdale,
Arizona
|
+$1.42M |
| 5 |
State Street
Boston,
Massachusetts
|
+$1.28M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
CAM
Cormorant Asset Management
Boston,
Massachusetts
|
-$2.96M |
| 2 |
UBS Group
Zurich,
Switzerland
|
-$1.66M |
| 3 |
SFI
Susquehanna Fundamental Investments
Bala Cynwyd,
Pennsylvania
|
-$1.21M |
| 4 |
BCM
Bridgeway Capital Management
Houston,
Texas
|
-$1.09M |
| 5 |
SC
Sculptor Capital
New York
|
-$929K |
OMER Hedge Fund Activity: Q1 2025 in Review
137 of the 7,471 institutional investors tracked by Wall St. Rank reported a position in Omeros (OMER) for Q1 2025, worth a combined $227M — down 14% from $262M a quarter earlier.
Buyers outnumbered sellers: 21 funds opened new OMER positions and 12 closed out — a net gain of 9 holders — while 35 added to existing stakes and 51 trimmed.
The largest buyer was Marshall Wace, adding an estimated $5.3M. The largest seller was Cormorant Asset Management, exiting entirely with an estimated $2.96M sold.
- 137 institutional investors held Omeros (OMER) as of Q1 2025, up from 128 in Q4 2024.
- Funds reported $227M of Omeros stock for Q1 2025, down 14% quarter-over-quarter.
- 21 funds opened new Omeros positions in Q1 2025 and 12 closed out, a net change of +9 holders.
- The largest Omeros buyer in Q1 2025 was Marshall Wace, an estimated $5.3M added.
- The largest Omeros seller in Q1 2025 was Cormorant Asset Management, an estimated $2.96M sold.
Based on aggregated 13F filings for Q1 2025.