Omeros
OMER
127 hedge funds and large institutions have $87.3M invested in Omeros in 2025 Q2 according to their latest regulatory filings, with 17 funds opening new positions, 45 increasing their positions, 35 reducing their positions, and 25 closing their positions.
29% more repeat investments, than reductions
Existing positions increased: 45 | Existing positions reduced: 35
2.1% more ownership
Funds ownership: 47.57% → 49.68% (+2.1%)
7% less funds holding
Funds holding: 136 → 127 (-9)
32% less first-time investments, than exits
New positions opened: 17 | Existing positions closed: 25
55% less call options, than puts
Call options by funds: $1.44M | Put options by funds: $3.19M
61% less capital invested
Capital invested by funds: $227M → $87.3M (-$139M)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Morgan Stanley
New York
|
+$2.96M |
| 2 |
Two Sigma Investments
New York
|
+$2.81M |
| 3 |
DIG
DeepCurrents Investment Group
New York
|
+$2.63M |
| 4 |
Two Sigma Advisers
New York
|
+$2.03M |
| 5 |
Renaissance Technologies
New York
|
+$1.91M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Nomura Holdings
Tokyo,
Japan
|
-$2.94M |
| 2 |
BlackRock
New York
|
-$1.65M |
| 3 |
D.E. Shaw & Co
New York
|
-$1.45M |
| 4 |
Corient Private Wealth
Miami,
Florida
|
-$945K |
| 5 |
State Street
Boston,
Massachusetts
|
-$777K |
OMER Hedge Fund Activity: Q2 2025 in Review
127 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Omeros (OMER) for Q2 2025, worth a combined $87.3M — down 61% from $227M a quarter earlier.
Sellers outnumbered buyers: 25 funds closed out of OMER and 17 opened new positions — a net loss of 8 holders — while 35 trimmed existing stakes and 45 added.
The largest buyer was Morgan Stanley, adding an estimated $2.96M. The largest seller was Nomura Holdings, cutting an estimated $2.94M.
- 127 institutional investors held Omeros (OMER) as of Q2 2025, down from 136 in Q1 2025.
- Funds reported $87.3M of Omeros stock for Q2 2025, down 61% quarter-over-quarter.
- 17 funds opened new Omeros positions in Q2 2025 and 25 closed out, a net change of -8 holders.
- The largest Omeros buyer in Q2 2025 was Morgan Stanley, an estimated $2.96M added.
- The largest Omeros seller in Q2 2025 was Nomura Holdings, an estimated $2.94M sold.
Based on aggregated 13F filings for Q2 2025.