Renaissance Technologies
OMER icon

Renaissance Technologies’s Omeros OMER Stock Holding History

Renaissance Technologies’s Portfolio OMER Stock Details OMER Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q4 		– Sell
-344,500
Closed -$1.41M – 3615
2025
Q3 		$1.41M Sell
344,500
-38,200
-10% -$152K ﹤0.01% 2298
2025
Q2 		$1.15M Buy
+382,700
New +$1.91M ﹤0.01% 2435
2023
Q4 		– Sell
-62,800
Closed -$183K – 4014
2023
Q3 		$183K Buy
+62,800
New +$252K ﹤0.01% 3117
2022
Q3 		– Sell
-540,400
Closed -$1.49M – 4315
2022
Q2 		$1.49M Buy
540,400
+246,800
+84% +$836K ﹤0.01% 2419
2022
Q1 		$1.76M Buy
293,600
+214,200
+270% +$1.34M ﹤0.01% 2322
2021
Q4 		$511K Buy
+79,400
New +$576K ﹤0.01% 3064
2021
Q3 		– Sell
-197,035
Closed -$2.92M – 3732
2021
Q2 		$2.92M Buy
+197,035
New +$3.31M ﹤0.01% 1996
2019
Q1 		– Sell
-67,235
Closed -$749K – 3626
2018
Q4 		$749K Buy
+67,235
New +$942K ﹤0.01% 2709
2015
Q4 		– Sell
-12,593
Closed -$138K – 3382
2015
Q3 		$138K Sell
12,593
-123,714
-91% -$1.93M ﹤0.01% 2959
2015
Q2 		$2.45M Buy
136,307
+71,872
+112% +$1.55M 0.01% 1927
2015
Q1 		$1.42M Buy
+64,435
New +$1.47M ﹤0.01% 2114
2013
Q3 		– Sell
-82,281
Closed -$415K – 2911
2013
Q2 		$415K Buy
+82,281
New +$379K ﹤0.01% 2300

Other funds holding OMER

BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
Vanguard Group
Vanguard Group Malvern, Pennsylvania $6.9T AUM 27.45% 1-Year Est. Return
ISL
Ingalls & Snyder LLC New York $2.83B AUM 21.61% 1-Year Est. Return
UBS Group
UBS Group Zurich, Switzerland $666B AUM 30.12% 1-Year Est. Return
Stifel Financial
Stifel Financial St. Louis, Missouri $109B AUM 21.36% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
Corient Private Wealth
Corient Private Wealth Miami, Florida $69.9B AUM 22.19% 1-Year Est. Return
KK
Kotler Kevin $427M AUM
D.E. Shaw & Co
D.E. Shaw & Co New York $166B AUM 43.98% 1-Year Est. Return

Renaissance Technologies's OMER Position: Q4 2025 in Review

Renaissance Technologies sold out of Omeros (OMER) in Q4 2025, closing a stake of 344,500 shares — an estimated $1.41M sold.

Renaissance Technologies first reported a position in OMER in Q2 2013 and held it in 12 quarters. The position peaked at $2.92M in Q2 2021. 149 funds tracked by Wall St. Rank hold OMER as of Q4 2025.

  • Renaissance Technologies reported no remaining Omeros position as of Q4 2025 after selling out during the quarter.
  • Renaissance Technologies sold 344,500 Omeros shares in Q4 2025, an estimated $1.41M.
  • Renaissance Technologies first reported a position in Omeros in Q2 2013 and held it in 12 quarters.
  • Renaissance Technologies's Omeros position peaked at $2.92M in Q2 2021.
  • 149 funds tracked by Wall St. Rank held Omeros as of Q4 2025.

Based on Renaissance Technologies's 13F filing for Q4 2025, filed 12 Feb 2026.