D.E. Shaw & Co
OMER icon

D.E. Shaw & Co’s Omeros OMER Stock Holding History

D.E. Shaw & Co’s Portfolio OMER Stock Details OMER Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$752K Sell
71,168
-683,831
-91% -$8.06M ﹤0.01% 3613
2025
Q4 		$13M Sell
754,999
-250,236
-25% -$2.15M 0.01% 1530
2025
Q3 		$4.12M Sell
1,005,235
-642,191
-39% -$2.55M ﹤0.01% 2381
2025
Q2 		$4.94M Sell
1,647,426
-291,102
-15% -$1.45M ﹤0.01% 2043
2025
Q1 		$15.9M Buy
1,938,528
+99,630
+5% +$880K 0.01% 1070
2024
Q4 		$18.2M Buy
1,838,898
+233,658
+15% +$1.6M 0.01% 1092
2024
Q3 		$6.37M Buy
1,605,240
+28,857
+2% +$123K 0.01% 1766
2024
Q2 		$6.4M Sell
1,576,383
-101,300
-6% -$362K 0.01% 1667
2024
Q1 		$5.79M Buy
1,677,683
+185,380
+12% +$705K 0.01% 1781
2023
Q4 		$4.88M Buy
1,492,303
+130,867
+10% +$276K ﹤0.01% 1929
2023
Q3 		$3.98M Sell
1,361,436
-277,766
-17% -$1.11M ﹤0.01% 2019
2023
Q2 		$8.92M Buy
1,639,202
+176,674
+12% +$1.03M 0.01% 1432
2023
Q1 		$6.8M Sell
1,462,528
-286,189
-16% -$1.03M 0.01% 1685
2022
Q4 		$3.95M Sell
1,748,717
-261,608
-13% -$722K ﹤0.01% 2315
2022
Q3 		$6.33M Sell
2,010,325
-148,256
-7% -$687K 0.01% 1816
2022
Q2 		$5.94M Buy
2,158,581
+322,094
+18% +$1.09M 0.01% 1926
2022
Q1 		$11M Sell
1,836,487
-76,834
-4% -$479K 0.01% 1514
2021
Q4 		$12.3M Sell
1,913,321
-167,265
-8% -$1.21M 0.01% 1475
2021
Q3 		$28.7M Sell
2,080,586
-288,231
-12% -$4.31M 0.03% 810
2021
Q2 		$35.2M Sell
2,368,817
-343,143
-13% -$5.76M 0.03% 719
2021
Q1 		$48.3M Sell
2,711,960
-39,345
-1% -$765K 0.05% 505
2020
Q4 		$39.3M Buy
2,751,305
+229,331
+9% +$2.8M 0.04% 609
2020
Q3 		$25.5M Buy
2,521,974
+553,706
+28% +$7.13M 0.03% 706
2020
Q2 		$29M Buy
1,968,268
+23,282
+1% +$348K 0.03% 586
2020
Q1 		$26M Buy
1,944,986
+159,835
+9% +$2.13M 0.04% 495
2019
Q4 		$25.2M Sell
1,785,151
-420,169
-19% -$6.15M 0.03% 698
2019
Q3 		$36M Sell
2,205,320
-79,223
-3% -$1.36M 0.04% 506
2019
Q2 		$35.8M Sell
2,284,543
-300,895
-12% -$5.4M 0.04% 492
2019
Q1 		$44.9M Buy
2,585,438
+673,194
+35% +$9.71M 0.06% 413
2018
Q4 		$21.3M Buy
1,912,244
+632,840
+49% +$8.87M 0.03% 686
2018
Q3 		$31.2M Buy
1,279,404
+372,877
+41% +$8.32M 0.04% 574
2018
Q2 		$16.4M Buy
906,527
+749,893
+479% +$13M 0.02% 834
2018
Q1 		$1.75M Sell
156,634
-340,193
-68% -$4.78M ﹤0.01% 2136
2017
Q4 		$9.65M Buy
496,827
+113,546
+30% +$2.13M 0.01% 1048
2017
Q3 		$8.29M Buy
+383,281
New +$8.12M 0.01% 1054
2017
Q1 		– Sell
-53,094
Closed -$527K – 3518
2016
Q4 		$527K Sell
53,094
-378,245
-88% -$3.86M ﹤0.01% 2820
2016
Q3 		$4.81M Buy
431,339
+60,954
+16% +$695K 0.01% 1327
2016
Q2 		$3.9M Sell
370,385
-107,963
-23% -$1.33M 0.01% 1440
2016
Q1 		$7.34M Buy
478,348
+122,160
+34% +$1.48M 0.01% 1035
2015
Q4 		$5.6M Buy
356,188
+143,653
+68% +$1.98M 0.01% 1325
2015
Q3 		$2.33M Sell
212,535
-543,690
-72% -$8.47M ﹤0.01% 1981
2015
Q2 		$13.6M Buy
756,225
+224,933
+42% +$4.85M 0.02% 834
2015
Q1 		$11.7M Buy
531,292
+128,052
+32% +$2.92M 0.02% 879
2014
Q4 		$9.99M Buy
403,240
+296,229
+277% +$5.4M 0.01% 1111
2014
Q3 		$1.36M Sell
107,011
-121,816
-53% -$1.71M ﹤0.01% 2551
2014
Q2 		$3.98M Buy
228,827
+1,288
+0.6% +$16.2K 0.01% 1781
2014
Q1 		$2.75M Buy
227,539
+98,547
+76% +$1.21M ﹤0.01% 2071
2013
Q4 		$1.46M Buy
128,992
+116,800
+958% +$1.13M ﹤0.01% 2829
2013
Q3 		$119K Buy
+12,192
New +$72.7K ﹤0.01% 4174

Other funds holding OMER

BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
ISL
Ingalls & Snyder LLC New York $2.83B AUM 21.61% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
UBS Group
UBS Group Zurich, Switzerland $666B AUM 30.12% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
Stifel Financial
Stifel Financial St. Louis, Missouri $109B AUM 21.36% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
Corient Private Wealth
Corient Private Wealth Miami, Florida $69.9B AUM 22.19% 1-Year Est. Return
VPM
Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM
Charles Schwab
Charles Schwab San Francisco, California $654B AUM 26.35% 1-Year Est. Return

D.E. Shaw & Co's OMER Position: Q1 2026 in Review

D.E. Shaw & Co reduced its Omeros (OMER) stake by 91% in Q1 2026, selling an estimated $8.06M and leaving 71,168 shares worth $752K. The position accounts for ﹤0.01% of the portfolio, ranked #3613.

D.E. Shaw & Co first reported a position in OMER in Q3 2013 and has held it in 49 quarters since. The position peaked at $48.3M in Q1 2021. 161 funds tracked by Wall St. Rank hold OMER as of Q1 2026.

  • D.E. Shaw & Co held 71,168 shares of Omeros worth $752K as of Q1 2026.
  • D.E. Shaw & Co sold 683,831 Omeros shares in Q1 2026, an estimated $8.06M.
  • Omeros made up ﹤0.01% of D.E. Shaw & Co's portfolio in Q1 2026, its #3613 holding.
  • D.E. Shaw & Co first reported a position in Omeros in Q3 2013 and has held it in 49 quarters since.
  • D.E. Shaw & Co's Omeros position peaked at $48.3M in Q1 2021.
  • 161 funds tracked by Wall St. Rank held Omeros as of Q1 2026.

Based on D.E. Shaw & Co's 13F filing for Q1 2026, filed 15 May 2026.