Jane Street’s Omeros OMER Stock Holding History

Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake
Trade Value Portfolio Weight Portfolio Position
2026
Q1
$1.53M Sell
145,307
-318,315
-69% -$3.75M ﹤0.01% 5594
2025
Q4
$7.96M Buy
463,622
+182,535
+65% +$1.57M ﹤0.01% 2611
2025
Q3
$1.15M Buy
281,087
+195,705
+229% +$776K ﹤0.01% 5999
2025
Q2
$256K Sell
85,382
-55,718
-39% -$278K ﹤0.01% 8130
2025
Q1
$1.16M Sell
141,100
-3,906
-3% -$34.5K ﹤0.01% 5292
2024
Q4
$1.43M Buy
145,006
+86,729
+149% +$595K ﹤0.01% 4728
2024
Q3
$231K Buy
58,277
+8,010
+16% +$34.2K ﹤0.01% 8431
2024
Q2
$204K Buy
50,267
+37,256
+286% +$133K ﹤0.01% 8354
2024
Q1
$44.9K Sell
13,011
-52,964
-80% -$201K ﹤0.01% 8762
2023
Q4
$216K Buy
65,975
+10,412
+19% +$22K ﹤0.01% 8103
2023
Q3
$162K Buy
+55,563
New +$223K ﹤0.01% 7745
2023
Q2
Sell
-296,910
Closed -$1.38M 9307
2023
Q1
$1.38M Buy
+296,910
New +$1.07M ﹤0.01% 4431
2022
Q4
Sell
-14,194
Closed -$45K 9834
2022
Q3
$45K Sell
14,194
-28,127
-66% -$130K ﹤0.01% 8972
2022
Q2
$116K Buy
42,321
+8,190
+24% +$27.8K ﹤0.01% 8547
2022
Q1
$205K Sell
34,131
-144,218
-81% -$900K ﹤0.01% 9000
2021
Q4
$1.15M Sell
178,349
-26,031
-13% -$189K ﹤0.01% 5615
2021
Q3
$2.82M Buy
204,380
+63,286
+45% +$947K ﹤0.01% 3778
2021
Q2
$2.09M Buy
141,094
+96,834
+219% +$1.63M ﹤0.01% 4248
2021
Q1
$788K Sell
44,260
-158,675
-78% -$3.09M ﹤0.01% 5924
2020
Q4
$2.9M Buy
202,935
+15,819
+8% +$193K ﹤0.01% 2866
2020
Q3
$1.89M Buy
187,116
+157,295
+527% +$2.03M ﹤0.01% 3127
2020
Q2
$439K Buy
29,821
+14,641
+96% +$219K ﹤0.01% 5267
2020
Q1
$203K Buy
+15,180
New +$202K ﹤0.01% 4637
2018
Q4
Sell
-12,686
Closed -$310K 5480
2018
Q3
$310K Buy
+12,686
New +$283K ﹤0.01% 4177
2018
Q2
Sell
-29,565
Closed -$330K 5425
2018
Q1
$330K Buy
29,565
+4,523
+18% +$63.5K ﹤0.01% 3916
2017
Q4
$487K Buy
+25,042
New +$470K ﹤0.01% 3216
2016
Q2
Sell
-26,052
Closed -$400K 4435
2016
Q1
$400K Buy
+26,052
New +$317K ﹤0.01% 2848
2014
Q3
Sell
-32,485
Closed -$565K 2910
2014
Q2
$565K Buy
+32,485
New +$410K 0.01% 1309
2014
Q1
Sell
-67,876
Closed -$766K 2957
2013
Q4
$766K Buy
+67,876
New +$655K 0.01% 934

Other funds holding OMER

Jane Street's OMER Position: Q1 2026 in Review

Jane Street reduced its Omeros (OMER) stake by 69% in Q1 2026, selling an estimated $3.75M and leaving 145,307 shares worth $1.53M. The position accounts for ﹤0.01% of the portfolio, ranked #5594.

Jane Street first reported a position in OMER in Q4 2013 and has held it in 29 quarters since. The position peaked at $7.96M in Q4 2025. 161 funds tracked by Wall St. Rank hold OMER as of Q1 2026.

  • Jane Street held 145,307 shares of Omeros worth $1.53M as of Q1 2026.
  • Jane Street sold 318,315 Omeros shares in Q1 2026, an estimated $3.75M.
  • Omeros made up ﹤0.01% of Jane Street's portfolio in Q1 2026, its #5594 holding.
  • Jane Street first reported a position in Omeros in Q4 2013 and has held it in 29 quarters since.
  • Jane Street's Omeros position peaked at $7.96M in Q4 2025.
  • 161 funds tracked by Wall St. Rank held Omeros as of Q1 2026.

Based on Jane Street's 13F filing for Q1 2026, filed 12 May 2026.