Jane Street
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Jane Street’s Omeros OMER Stock Holding History

Jane Street’s Portfolio OMER Stock Details OMER Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$1.29M Buy
122,500
+13,000
+12% +$153K ﹤0.01% 5943
2025
Q4 		$1.88M Buy
109,500
+95,200
+666% +$820K ﹤0.01% 4932
2025
Q3 		$58.6K Buy
+14,300
New +$56.7K ﹤0.01% 10303
2025
Q2 		– Sell
-46,900
Closed -$386K – 10501
2025
Q1 		$386K Sell
46,900
-168,200
-78% -$1.48M ﹤0.01% 7357
2024
Q4 		$2.13M Buy
+215,100
New +$1.48M ﹤0.01% 4010
2022
Q4 		– Sell
-11,200
Closed -$35K – 9833
2022
Q3 		$35K Buy
+11,200
New +$51.9K ﹤0.01% 9049
2022
Q2 		– Sell
-16,000
Closed -$96K – 10508
2022
Q1 		$96K Sell
16,000
-38,200
-70% -$238K ﹤0.01% 9474
2021
Q4 		$349K Sell
54,200
-49,700
-48% -$360K ﹤0.01% 7902
2021
Q3 		$1.43M Sell
103,900
-14,500
-12% -$217K ﹤0.01% 5177
2021
Q2 		$1.76M Buy
118,400
+77,900
+192% +$1.31M ﹤0.01% 4578
2021
Q1 		$721K Sell
40,500
-3,700
-8% -$72K ﹤0.01% 6102
2020
Q4 		$631K Sell
44,200
-261,300
-86% -$3.19M ﹤0.01% 5389
2020
Q3 		$3.09M Buy
305,500
+251,100
+462% +$3.23M ﹤0.01% 2405
2020
Q2 		$801K Buy
54,400
+19,800
+57% +$296K ﹤0.01% 4396
2020
Q1 		$463K Sell
34,600
-17,000
-33% -$226K ﹤0.01% 3697
2019
Q4 		$727K Buy
+51,600
New +$755K ﹤0.01% 3210
2019
Q2 		– Sell
-14,100
Closed -$245K – 5570
2019
Q1 		$245K Buy
+14,100
New +$203K ﹤0.01% 4461
2018
Q4 		– Sell
-20,500
Closed -$500K – 5479
2018
Q3 		$500K Buy
+20,500
New +$457K ﹤0.01% 3617
2018
Q2 		– Sell
-12,800
Closed -$143K – 5424
2018
Q1 		$143K Buy
+12,800
New +$180K ﹤0.01% 4533
2017
Q3 		– Sell
-34,900
Closed -$695K – 4887
2017
Q2 		$695K Buy
34,900
+12,600
+57% +$220K ﹤0.01% 2616
2017
Q1 		$337K Buy
+22,300
New +$244K ﹤0.01% 3296

Other funds holding OMER

BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
ISL
Ingalls & Snyder LLC New York $2.83B AUM 21.61% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
UBS Group
UBS Group Zurich, Switzerland $666B AUM 30.12% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
Stifel Financial
Stifel Financial St. Louis, Missouri $109B AUM 21.36% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
Corient Private Wealth
Corient Private Wealth Miami, Florida $69.9B AUM 22.19% 1-Year Est. Return
VPM
Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM
Charles Schwab
Charles Schwab San Francisco, California $654B AUM 26.35% 1-Year Est. Return

Jane Street's OMER Position: Q1 2026 in Review

Jane Street reduced its Omeros (OMER) stake by 69% in Q1 2026, selling an estimated $3.75M and leaving 145,307 shares worth $1.53M. The position accounts for ﹤0.01% of the portfolio, ranked #5594.

Jane Street first reported a position in OMER in Q4 2013 and has held it in 29 quarters since. The position peaked at $7.96M in Q4 2025. 161 funds tracked by Wall St. Rank hold OMER as of Q1 2026.

  • Jane Street held 145,307 shares of Omeros worth $1.53M as of Q1 2026.
  • Jane Street sold 318,315 Omeros shares in Q1 2026, an estimated $3.75M.
  • Omeros made up ﹤0.01% of Jane Street's portfolio in Q1 2026, its #5594 holding.
  • Jane Street first reported a position in Omeros in Q4 2013 and has held it in 29 quarters since.
  • Jane Street's Omeros position peaked at $7.96M in Q4 2025.
  • 161 funds tracked by Wall St. Rank held Omeros as of Q1 2026.

Based on Jane Street's 13F filing for Q1 2026, filed 12 May 2026.