Jane Street’s Mereo BioPharma MREO Stock Holding History

Jane Street’s Portfolio MREO Stock Details MREO Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q1	$37K	Sell	112,200 -238,200	-68%	-$102K	﹤0.01%	11067
2025 Q4	$146K	Buy	+350,400	New	+$667K	﹤0.01%	9952
2025 Q3	–	Sell	-221,700	Closed	-$601K	–	11406
2025 Q2	$601K	Buy	221,700 +4,400	+2%	+$10.6K	﹤0.01%	6577
2025 Q1	$489K	Buy	217,300 +8,900	+4%	+$25.2K	﹤0.01%	6903
2024 Q4	$729K	Hold	208,400	–	–	﹤0.01%	5983
2024 Q3	$857K	Sell	208,400 -100	-0%	-$414	﹤0.01%	6191
2024 Q2	$751K	Buy	+208,500	New	+$675K	﹤0.01%	6324

Other funds holding MREO

RCMNY

Rubric Capital Management (New York) New York $9.44B AUM 68.42% 1-Year Est. Return

EcoR1 Capital San Francisco, California $2.36B AUM 204.53% 1-Year Est. Return

6CM

683 Capital Management New York $1.92B AUM 85.52% 1-Year Est. Return

Bank of America Charlotte, North Carolina $1.37T AUM 24.88% 1-Year Est. Return

DCM

Defilade Capital Management Emeryville, California $712M AUM

Newtyn Management New York $936M AUM 27.23% 1-Year Est. Return

Millennium Management New York $240B AUM 35.51% 1-Year Est. Return

Tejara Capital London, United Kingdom $303M AUM 5.43% 1-Year Est. Return

UBS Group Zurich, Switzerland $666B AUM 30.12% 1-Year Est. Return

WANY

Wealthspire Advisors (New York) New York $12.7B AUM 17.31% 1-Year Est. Return

Jane Street's MREO Position: Q1 2026 in Review

Jane Street reduced its Mereo BioPharma (MREO) stake by 61% in Q1 2026, selling an estimated $92.7K and leaving 139,973 shares worth $46.2K. The position accounts for ﹤0.01% of the portfolio, ranked #11003.

Jane Street first reported a position in MREO in Q4 2020 and has held it in 17 quarters since. The position peaked at $932K in Q3 2025. 63 funds tracked by Wall St. Rank hold MREO as of Q1 2026.

Jane Street held 139,973 shares of Mereo BioPharma worth $46.2K as of Q1 2026.
Jane Street sold 216,031 Mereo BioPharma shares in Q1 2026, an estimated $92.7K.
Mereo BioPharma made up ﹤0.01% of Jane Street's portfolio in Q1 2026, its #11003 holding.
Jane Street first reported a position in Mereo BioPharma in Q4 2020 and has held it in 17 quarters since.
Jane Street's Mereo BioPharma position peaked at $932K in Q3 2025.
63 funds tracked by Wall St. Rank held Mereo BioPharma as of Q1 2026.

Based on Jane Street's 13F filing for Q1 2026, filed 12 May 2026.