Jane Street
MREO

Jane Street’s Mereo BioPharma MREO Stock Holding History

Jane Street’s Portfolio MREO Stock Details MREO Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$3.75K Sell
11,800
-69,800
-86% -$20.9K ﹤0.01% 11353
2026
Q1 		$26.9K Sell
81,600
-85,700
-51% -$36.8K ﹤0.01% 11136
2025
Q4 		$69.7K Buy
167,300
+135,100
+420% +$257K ﹤0.01% 10372
2025
Q3 		$66.3K Buy
32,200
+5,200
+19% +$9.59K ﹤0.01% 10267
2025
Q2 		$73.2K Buy
27,000
+15,100
+127% +$36.4K ﹤0.01% 9077
2025
Q1 		$26.8K Buy
+11,900
New +$33.7K ﹤0.01% 9108

Other funds holding MREO

RCMNY
Rubric Capital Management (New York) New York $10.9B AUM 70.31% 1-Year Est. Return
6CM
683 Capital Management New York $2.04B AUM 94.26% 1-Year Est. Return
Bank of America
Bank of America Charlotte, North Carolina $1.55T AUM 33.47% 1-Year Est. Return
DCM
Defilade Capital Management Emeryville, California $747M AUM
NM
Newtyn Management New York $801M AUM 23.14% 1-Year Est. Return
TC
Tejara Capital London, United Kingdom $243M AUM 9.84% 1-Year Est. Return
UBS Group
UBS Group Zurich, Switzerland $786B AUM 40.34% 1-Year Est. Return
Two Sigma Investments
Two Sigma Investments New York $138B AUM 41.87% 1-Year Est. Return
EC
EcoR1 Capital San Francisco, California $2.06B AUM 215.32% 1-Year Est. Return
II
Ishara Investments Los Angeles, California $136M AUM

Jane Street's MREO Position: Q2 2026 in Review

Jane Street increased its Mereo BioPharma (MREO) stake by 454% in Q2 2026, buying an estimated $190K and bringing the position to 774,944 shares worth $246K. The position accounts for ﹤0.01% of the portfolio, ranked #9638.

Jane Street first reported a position in MREO in Q4 2020 and has held it in 18 quarters since. The position peaked at $932K in Q3 2025. 61 funds tracked by Wall St. Rank hold MREO as of Q2 2026.

  • Jane Street held 774,944 shares of Mereo BioPharma worth $246K as of Q2 2026.
  • Jane Street bought 634,971 Mereo BioPharma shares in Q2 2026, an estimated $190K.
  • Mereo BioPharma made up ﹤0.01% of Jane Street's portfolio in Q2 2026, its #9638 holding.
  • Jane Street first reported a position in Mereo BioPharma in Q4 2020 and has held it in 18 quarters since.
  • Jane Street's Mereo BioPharma position peaked at $932K in Q3 2025.
  • 61 funds tracked by Wall St. Rank held Mereo BioPharma as of Q2 2026.

Based on Jane Street's 13F filing for Q2 2026, filed 14 Aug 2026.