Jane Street
MREO

Jane Street’s Mereo BioPharma MREO Stock Holding History

Jane Street’s Portfolio MREO Stock Details MREO Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$26.9K Sell
81,600
-85,700
-51% -$36.8K ﹤0.01% 11136
2025
Q4 		$69.7K Buy
167,300
+135,100
+420% +$257K ﹤0.01% 10372
2025
Q3 		$66.3K Buy
32,200
+5,200
+19% +$9.59K ﹤0.01% 10267
2025
Q2 		$73.2K Buy
27,000
+15,100
+127% +$36.4K ﹤0.01% 9077
2025
Q1 		$26.8K Buy
+11,900
New +$33.7K ﹤0.01% 9108

Other funds holding MREO

RCMNY
Rubric Capital Management (New York) New York $9.44B AUM 68.42% 1-Year Est. Return
EC
EcoR1 Capital San Francisco, California $2.36B AUM 204.53% 1-Year Est. Return
6CM
683 Capital Management New York $1.92B AUM 85.52% 1-Year Est. Return
Bank of America
Bank of America Charlotte, North Carolina $1.37T AUM 24.88% 1-Year Est. Return
DCM
Defilade Capital Management Emeryville, California $712M AUM
NM
Newtyn Management New York $936M AUM 27.23% 1-Year Est. Return
Millennium Management
Millennium Management New York $240B AUM 35.51% 1-Year Est. Return
TC
Tejara Capital London, United Kingdom $303M AUM 5.43% 1-Year Est. Return
UBS Group
UBS Group Zurich, Switzerland $666B AUM 30.12% 1-Year Est. Return
WANY
Wealthspire Advisors (New York) New York $12.7B AUM 17.31% 1-Year Est. Return

Jane Street's MREO Position: Q1 2026 in Review

Jane Street reduced its Mereo BioPharma (MREO) stake by 61% in Q1 2026, selling an estimated $92.7K and leaving 139,973 shares worth $46.2K. The position accounts for ﹤0.01% of the portfolio, ranked #11003.

Jane Street first reported a position in MREO in Q4 2020 and has held it in 17 quarters since. The position peaked at $932K in Q3 2025. 63 funds tracked by Wall St. Rank hold MREO as of Q1 2026.

  • Jane Street held 139,973 shares of Mereo BioPharma worth $46.2K as of Q1 2026.
  • Jane Street sold 216,031 Mereo BioPharma shares in Q1 2026, an estimated $92.7K.
  • Mereo BioPharma made up ﹤0.01% of Jane Street's portfolio in Q1 2026, its #11003 holding.
  • Jane Street first reported a position in Mereo BioPharma in Q4 2020 and has held it in 17 quarters since.
  • Jane Street's Mereo BioPharma position peaked at $932K in Q3 2025.
  • 63 funds tracked by Wall St. Rank held Mereo BioPharma as of Q1 2026.

Based on Jane Street's 13F filing for Q1 2026, filed 12 May 2026.