Jane Street
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Jane Street’s Madrigal Pharmaceuticals MDGL Stock Holding History

Jane Street’s Portfolio MDGL Stock Details MDGL Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q3 		$18.8M Sell
37,400
-21,700
-37% -$11.5M ﹤0.01% 2142
2026
Q2 		$31.7M Sell
59,100
-19,000
-24% -$9.7M ﹤0.01% 1753
2026
Q1 		$40.9M Buy
78,100
+23,200
+42% +$11.1M 0.01% 1194
2025
Q4 		$32M Buy
54,900
+10,300
+23% +$5.26M ﹤0.01% 1214
2025
Q3 		$20.5M Sell
44,600
-4,900
-10% -$1.83M ﹤0.01% 1639
2025
Q2 		$15M Sell
49,500
-2,500
-5% -$745K ﹤0.01% 1728
2025
Q1 		$17.2M Sell
52,000
-174,400
-77% -$57.3M ﹤0.01% 1423
2024
Q4 		$69.9M Buy
226,400
+14,900
+7% +$4.19M 0.02% 555
2024
Q3 		$44.9M Buy
211,500
+26,200
+14% +$6.7M 0.01% 741
2024
Q2 		$51.9M Sell
185,300
-12,100
-6% -$2.88M 0.01% 678
2024
Q1 		$52.7M Sell
197,400
-18,000
-8% -$4.24M 0.01% 605
2023
Q4 		$49.8M Buy
215,400
+21,100
+11% +$3.69M 0.01% 679
2023
Q3 		$28.4M Buy
194,300
+102,400
+111% +$19.3M 0.01% 844
2023
Q2 		$21.2M Buy
91,900
+39,200
+74% +$10.6M 0.01% 1150
2023
Q1 		$12.8M Sell
52,700
-76,100
-59% -$20.7M 0.01% 1388
2022
Q4 		$37.4M Buy
128,800
+89,400
+227% +$8.74M 0.02% 655
2022
Q3 		$2.56M Buy
39,400
+3,100
+9% +$215K ﹤0.01% 3741
2022
Q2 		$2.6M Buy
36,300
+4,300
+13% +$316K ﹤0.01% 3694
2022
Q1 		$3.14M Buy
32,000
+20,200
+171% +$1.7M ﹤0.01% 3850
2021
Q4 		$1M Buy
11,800
+5,400
+84% +$444K ﹤0.01% 5893
2021
Q3 		$511K Sell
6,400
-1,200
-16% -$104K ﹤0.01% 7245
2021
Q2 		$740K Sell
7,600
-1,200
-14% -$142K ﹤0.01% 6475
2021
Q1 		$1.03M Buy
+8,800
New +$1.03M ﹤0.01% 5396
2020
Q4 		– Sell
-26,100
Closed -$3.1M – 7850
2020
Q3 		$3.1M Sell
26,100
-5,300
-17% -$575K ﹤0.01% 2400
2020
Q2 		$3.56M Buy
+31,400
New +$3.09M ﹤0.01% 2270

Other funds holding MDGL

BlackRock
BlackRock New York $6.79T AUM 37.06% 1-Year Est. Return
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.76T AUM
Vanguard Portfolio Management
Vanguard Portfolio Management Malvern, Pennsylvania $2.21T AUM
State Street
State Street Boston, Massachusetts $3.44T AUM 36.12% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.92T AUM 36.1% 1-Year Est. Return
William Blair Investment Management
William Blair Investment Management Chicago, Illinois $30.8B AUM 33.92% 1-Year Est. Return
Invesco
Invesco Atlanta, Georgia $1.27T AUM 50.62% 1-Year Est. Return
Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.32T AUM 44.66% 1-Year Est. Return
Lord, Abbett & Co
Lord, Abbett & Co Jersey City, New Jersey $33.4B AUM 56.97% 1-Year Est. Return
Artisan Partners
Artisan Partners Milwaukee, Wisconsin $54.9B AUM 27.38% 1-Year Est. Return

Jane Street's MDGL Position: Q3 2026 in Review

Jane Street reduced its Madrigal Pharmaceuticals (MDGL) stake by 46% in Q3 2026, selling an estimated $46.4M and leaving 103,748 shares worth $52.3M. The position accounts for ﹤0.01% of the portfolio, ranked #1280.

Jane Street first reported a position in MDGL in Q2 2013 and has held it in 35 quarters since. The position peaked at $103M in Q2 2026. 332 funds tracked by Wall St. Rank hold MDGL as of Q3 2026.

  • Jane Street held 103,748 shares of Madrigal Pharmaceuticals worth $52.3M as of Q3 2026.
  • Jane Street sold 87,793 Madrigal Pharmaceuticals shares in Q3 2026, an estimated $46.4M.
  • Madrigal Pharmaceuticals made up ﹤0.01% of Jane Street's portfolio in Q3 2026, its #1280 holding.
  • Jane Street first reported a position in Madrigal Pharmaceuticals in Q2 2013 and has held it in 35 quarters since.
  • Jane Street's Madrigal Pharmaceuticals position peaked at $103M in Q2 2026.
  • 332 funds tracked by Wall St. Rank held Madrigal Pharmaceuticals as of Q3 2026.

Based on Jane Street's 13F filing for Q3 2026, filed 12 Nov 2026.