Jane Street
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Jane Street’s Madrigal Pharmaceuticals MDGL Stock Holding History

Jane Street’s Portfolio MDGL Stock Details MDGL Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$31.7M Sell
59,100
-19,000
-24% -$9.73M ﹤0.01% 1753
2026
Q1 		$40.9M Buy
78,100
+23,200
+42% +$11.1M 0.01% 1194
2025
Q4 		$32M Buy
54,900
+10,300
+23% +$5.26M ﹤0.01% 1214
2025
Q3 		$20.5M Sell
44,600
-4,900
-10% -$1.83M ﹤0.01% 1639
2025
Q2 		$15M Sell
49,500
-2,500
-5% -$745K ﹤0.01% 1728
2025
Q1 		$17.2M Sell
52,000
-174,400
-77% -$57.3M ﹤0.01% 1423
2024
Q4 		$69.9M Buy
226,400
+14,900
+7% +$4.19M 0.02% 555
2024
Q3 		$44.9M Buy
211,500
+26,200
+14% +$6.7M 0.01% 741
2024
Q2 		$51.9M Sell
185,300
-12,100
-6% -$2.88M 0.01% 678
2024
Q1 		$52.7M Sell
197,400
-18,000
-8% -$4.24M 0.01% 605
2023
Q4 		$49.8M Buy
215,400
+21,100
+11% +$3.69M 0.01% 679
2023
Q3 		$28.4M Buy
194,300
+102,400
+111% +$19.3M 0.01% 844
2023
Q2 		$21.2M Buy
91,900
+39,200
+74% +$10.6M 0.01% 1150
2023
Q1 		$12.8M Sell
52,700
-76,100
-59% -$20.7M 0.01% 1388
2022
Q4 		$37.4M Buy
128,800
+89,400
+227% +$8.74M 0.02% 655
2022
Q3 		$2.56M Buy
39,400
+3,100
+9% +$215K ﹤0.01% 3741
2022
Q2 		$2.6M Buy
36,300
+4,300
+13% +$316K ﹤0.01% 3694
2022
Q1 		$3.14M Buy
32,000
+20,200
+171% +$1.7M ﹤0.01% 3850
2021
Q4 		$1M Buy
11,800
+5,400
+84% +$444K ﹤0.01% 5893
2021
Q3 		$511K Sell
6,400
-1,200
-16% -$104K ﹤0.01% 7245
2021
Q2 		$740K Sell
7,600
-1,200
-14% -$142K ﹤0.01% 6475
2021
Q1 		$1.03M Buy
+8,800
New +$1.03M ﹤0.01% 5396
2020
Q4 		– Sell
-26,100
Closed -$3.1M – 7850
2020
Q3 		$3.1M Sell
26,100
-5,300
-17% -$575K ﹤0.01% 2400
2020
Q2 		$3.56M Buy
+31,400
New +$3.09M ﹤0.01% 2270

Other funds holding MDGL

BBA
Baker Bros. Advisors New York $20B AUM 154.41% 1-Year Est. Return
RI
RTW Investments New York $11.7B AUM 174.13% 1-Year Est. Return
JT
Jupiter Topco New York $245B AUM
ACA
Avoro Capital Advisors New York $11.1B AUM 207.82% 1-Year Est. Return
PC
Paulson & Co New York $2.58B AUM 68.51% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
Wellington Management Group
Wellington Management Group Boston, Massachusetts $580B AUM 38.23% 1-Year Est. Return
Vanguard Portfolio Management
Vanguard Portfolio Management Malvern, Pennsylvania $2.22T AUM
State Street
State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return

Jane Street's MDGL Position: Q2 2026 in Review

Jane Street increased its Madrigal Pharmaceuticals (MDGL) stake by 434% in Q2 2026, buying an estimated $79.8M and bringing the position to 191,541 shares worth $103M. The position accounts for 0.01% of the portfolio, ranked #923.

Jane Street first reported a position in MDGL in Q2 2013 and has held it in 34 quarters since. 414 funds tracked by Wall St. Rank hold MDGL as of Q2 2026.

  • Jane Street held 191,541 shares of Madrigal Pharmaceuticals worth $103M as of Q2 2026.
  • Jane Street bought 155,703 Madrigal Pharmaceuticals shares in Q2 2026, an estimated $79.8M.
  • Madrigal Pharmaceuticals made up 0.01% of Jane Street's portfolio in Q2 2026, its #923 holding.
  • Jane Street first reported a position in Madrigal Pharmaceuticals in Q2 2013 and has held it in 34 quarters since.
  • 414 funds tracked by Wall St. Rank held Madrigal Pharmaceuticals as of Q2 2026.

Based on Jane Street's 13F filing for Q2 2026, filed 14 Aug 2026.