Jane Street
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Jane Street’s Madrigal Pharmaceuticals MDGL Stock Holding History

Jane Street’s Portfolio MDGL Stock Details MDGL Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$40.9M Buy
78,100
+23,200
+42% +$11.1M 0.01% 1194
2025
Q4 		$32M Buy
54,900
+10,300
+23% +$5.26M ﹤0.01% 1214
2025
Q3 		$20.5M Sell
44,600
-4,900
-10% -$1.83M ﹤0.01% 1639
2025
Q2 		$15M Sell
49,500
-2,500
-5% -$745K ﹤0.01% 1728
2025
Q1 		$17.2M Sell
52,000
-174,400
-77% -$57.3M ﹤0.01% 1423
2024
Q4 		$69.9M Buy
226,400
+14,900
+7% +$4.19M 0.02% 555
2024
Q3 		$44.9M Buy
211,500
+26,200
+14% +$6.7M 0.01% 741
2024
Q2 		$51.9M Sell
185,300
-12,100
-6% -$2.88M 0.01% 678
2024
Q1 		$52.7M Sell
197,400
-18,000
-8% -$4.24M 0.01% 605
2023
Q4 		$49.8M Buy
215,400
+21,100
+11% +$3.69M 0.01% 679
2023
Q3 		$28.4M Buy
194,300
+102,400
+111% +$19.3M 0.01% 844
2023
Q2 		$21.2M Buy
91,900
+39,200
+74% +$10.6M 0.01% 1150
2023
Q1 		$12.8M Sell
52,700
-76,100
-59% -$20.7M 0.01% 1388
2022
Q4 		$37.4M Buy
128,800
+89,400
+227% +$8.74M 0.02% 655
2022
Q3 		$2.56M Buy
39,400
+3,100
+9% +$215K ﹤0.01% 3741
2022
Q2 		$2.6M Buy
36,300
+4,300
+13% +$316K ﹤0.01% 3694
2022
Q1 		$3.14M Buy
32,000
+20,200
+171% +$1.7M ﹤0.01% 3850
2021
Q4 		$1M Buy
11,800
+5,400
+84% +$444K ﹤0.01% 5893
2021
Q3 		$511K Sell
6,400
-1,200
-16% -$104K ﹤0.01% 7245
2021
Q2 		$740K Sell
7,600
-1,200
-14% -$142K ﹤0.01% 6475
2021
Q1 		$1.03M Buy
+8,800
New +$1.03M ﹤0.01% 5396
2020
Q4 		– Sell
-26,100
Closed -$3.1M – 7850
2020
Q3 		$3.1M Sell
26,100
-5,300
-17% -$575K ﹤0.01% 2400
2020
Q2 		$3.56M Buy
+31,400
New +$3.09M ﹤0.01% 2270

Other funds holding MDGL

BBA
Baker Bros. Advisors New York $17.4B AUM 131.5% 1-Year Est. Return
Janus Henderson Group
Janus Henderson Group London, United Kingdom $209B AUM 37.72% 1-Year Est. Return
RI
RTW Investments New York $10B AUM 135.35% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $10.2B AUM 149.19% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
PC
Paulson & Co New York $3.11B AUM 94.93% 1-Year Est. Return
VPM
Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
Wellington Management Group
Wellington Management Group Boston, Massachusetts $535B AUM 26.23% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return

Jane Street's MDGL Position: Q1 2026 in Review

Jane Street reduced its Madrigal Pharmaceuticals (MDGL) stake by 62% in Q1 2026, selling an estimated $27.4M and leaving 35,838 shares worth $18.8M. The position accounts for ﹤0.01% of the portfolio, ranked #1837.

Jane Street first reported a position in MDGL in Q2 2013 and has held it in 33 quarters since. The position peaked at $54.2M in Q4 2025. 378 funds tracked by Wall St. Rank hold MDGL as of Q1 2026.

  • Jane Street held 35,838 shares of Madrigal Pharmaceuticals worth $18.8M as of Q1 2026.
  • Jane Street sold 57,276 Madrigal Pharmaceuticals shares in Q1 2026, an estimated $27.4M.
  • Madrigal Pharmaceuticals made up ﹤0.01% of Jane Street's portfolio in Q1 2026, its #1837 holding.
  • Jane Street first reported a position in Madrigal Pharmaceuticals in Q2 2013 and has held it in 33 quarters since.
  • Jane Street's Madrigal Pharmaceuticals position peaked at $54.2M in Q4 2025.
  • 378 funds tracked by Wall St. Rank held Madrigal Pharmaceuticals as of Q1 2026.

Based on Jane Street's 13F filing for Q1 2026, filed 12 May 2026.