Jane Street
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Jane Street’s Madrigal Pharmaceuticals MDGL Stock Holding History

Jane Street’s Portfolio MDGL Stock Details MDGL Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$65.6M Sell
125,300
-3,100
-2% -$1.48M 0.01% 890
2025
Q4 		$74.8M Sell
128,400
-27,700
-18% -$14.1M 0.01% 715
2025
Q3 		$71.6M Sell
156,100
-154,000
-50% -$57.5M 0.01% 752
2025
Q2 		$93.8M Buy
310,100
+36,900
+14% +$11M 0.02% 489
2025
Q1 		$90.5M Sell
273,200
-89,300
-25% -$29.3M 0.02% 420
2024
Q4 		$112M Buy
362,500
+177,500
+96% +$49.9M 0.02% 398
2024
Q3 		$39.3M Buy
185,000
+18,000
+11% +$4.6M 0.01% 807
2024
Q2 		$46.8M Sell
167,000
-53,200
-24% -$12.7M 0.01% 728
2024
Q1 		$58.8M Buy
220,200
+10,300
+5% +$2.43M 0.01% 556
2023
Q4 		$48.6M Sell
209,900
-55,700
-21% -$9.75M 0.01% 695
2023
Q3 		$38.8M Sell
265,600
-49,800
-16% -$9.37M 0.01% 679
2023
Q2 		$72.9M Buy
315,400
+127,300
+68% +$34.5M 0.02% 449
2023
Q1 		$45.6M Sell
188,100
-77,900
-29% -$21.2M 0.02% 563
2022
Q4 		$77.2M Buy
266,000
+223,600
+527% +$21.9M 0.04% 371
2022
Q3 		$2.76M Sell
42,400
-25,300
-37% -$1.76M ﹤0.01% 3604
2022
Q2 		$4.85M Buy
67,700
+51,200
+310% +$3.76M ﹤0.01% 2696
2022
Q1 		$1.62M Buy
16,500
+12,500
+313% +$1.05M ﹤0.01% 5154
2021
Q4 		$339K Sell
4,000
-5,100
-56% -$419K ﹤0.01% 7952
2021
Q3 		$726K Buy
9,100
+7,000
+333% +$605K ﹤0.01% 6565
2021
Q2 		$205K Sell
2,100
-3,300
-61% -$391K ﹤0.01% 8777
2021
Q1 		$632K Sell
5,400
-1,500
-22% -$175K ﹤0.01% 6371
2020
Q4 		$767K Sell
6,900
-6,000
-47% -$733K ﹤0.01% 5092
2020
Q3 		$1.53M Sell
12,900
-17,600
-58% -$1.91M ﹤0.01% 3430
2020
Q2 		$3.45M Buy
+30,500
New +$3M ﹤0.01% 2315
2020
Q1 		– Sell
-2,500
Closed -$228K – 5716
2019
Q4 		$228K Buy
+2,500
New +$242K ﹤0.01% 4586

Other funds holding MDGL

BBA
Baker Bros. Advisors New York $17.4B AUM 131.5% 1-Year Est. Return
Janus Henderson Group
Janus Henderson Group London, United Kingdom $209B AUM 37.72% 1-Year Est. Return
RI
RTW Investments New York $10B AUM 135.35% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $10.2B AUM 149.19% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
PC
Paulson & Co New York $3.11B AUM 94.93% 1-Year Est. Return
VPM
Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
Wellington Management Group
Wellington Management Group Boston, Massachusetts $535B AUM 26.23% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return

Jane Street's MDGL Position: Q1 2026 in Review

Jane Street reduced its Madrigal Pharmaceuticals (MDGL) stake by 62% in Q1 2026, selling an estimated $27.4M and leaving 35,838 shares worth $18.8M. The position accounts for ﹤0.01% of the portfolio, ranked #1837.

Jane Street first reported a position in MDGL in Q2 2013 and has held it in 33 quarters since. The position peaked at $54.2M in Q4 2025. 378 funds tracked by Wall St. Rank hold MDGL as of Q1 2026.

  • Jane Street held 35,838 shares of Madrigal Pharmaceuticals worth $18.8M as of Q1 2026.
  • Jane Street sold 57,276 Madrigal Pharmaceuticals shares in Q1 2026, an estimated $27.4M.
  • Madrigal Pharmaceuticals made up ﹤0.01% of Jane Street's portfolio in Q1 2026, its #1837 holding.
  • Jane Street first reported a position in Madrigal Pharmaceuticals in Q2 2013 and has held it in 33 quarters since.
  • Jane Street's Madrigal Pharmaceuticals position peaked at $54.2M in Q4 2025.
  • 378 funds tracked by Wall St. Rank held Madrigal Pharmaceuticals as of Q1 2026.

Based on Jane Street's 13F filing for Q1 2026, filed 12 May 2026.