Jane Street
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Jane Street’s Structure Therapeutics GPCR Stock Holding History

Jane Street’s Portfolio GPCR Stock Details GPCR Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		– Sell
-147,217
Closed -$10.1M – 12101
2025
Q4 		$10.2M Buy
+147,217
New +$6.01M ﹤0.01% 2290
2025
Q2 		– Sell
-120,703
Closed -$2.65M – 10102
2025
Q1 		$2.09M Buy
120,703
+4,690
+4% +$115K ﹤0.01% 4277
2024
Q4 		$3.15M Buy
116,013
+77,176
+199% +$2.74M ﹤0.01% 3361
2024
Q3 		$1.7M Sell
38,837
-70,318
-64% -$2.72M ﹤0.01% 4808
2024
Q2 		$4.29M Buy
109,155
+101,485
+1,323% +$4.17M ﹤0.01% 3215
2024
Q1 		$329K Sell
7,670
-31,128
-80% -$1.31M ﹤0.01% 7409
2023
Q4 		$1.58M Buy
+38,798
New +$2.22M ﹤0.01% 4743

Other funds holding GPCR

Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return
Wellington Management Group
Wellington Management Group Boston, Massachusetts $580B AUM 38.23% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $11.1B AUM 207.82% 1-Year Est. Return
JT
Jupiter Topco New York $245B AUM
DTC
Deep Track Capital Greenwich, Connecticut $6.87B AUM 205.24% 1-Year Est. Return
BI
BVF Inc San Francisco, California $3.91B AUM 304.52% 1-Year Est. Return
Morgan Stanley
Morgan Stanley New York $1.89T AUM 35.08% 1-Year Est. Return
O
OrbiMed New York $5.4B AUM 163.13% 1-Year Est. Return
Principal Financial Group
Principal Financial Group Des Moines, Iowa $204B AUM 27.99% 1-Year Est. Return
American Century Companies
American Century Companies Kansas City, Missouri $226B AUM 44.75% 1-Year Est. Return

Jane Street's GPCR Position: Q1 2026 in Review

Jane Street sold out of Structure Therapeutics (GPCR) in Q1 2026, closing a stake of 147,217 shares — an estimated $10.1M sold.

Jane Street first reported a position in GPCR in Q4 2023 and held it in 7 quarters. The position peaked at $10.2M in Q4 2025. 196 funds tracked by Wall St. Rank hold GPCR as of Q1 2026.

  • Jane Street reported no remaining Structure Therapeutics position as of Q1 2026 after selling out during the quarter.
  • Jane Street sold 147,217 Structure Therapeutics shares in Q1 2026, an estimated $10.1M.
  • Jane Street first reported a position in Structure Therapeutics in Q4 2023 and held it in 7 quarters.
  • Jane Street's Structure Therapeutics position peaked at $10.2M in Q4 2025.
  • 196 funds tracked by Wall St. Rank held Structure Therapeutics as of Q1 2026.

Based on Jane Street's 13F filing for Q1 2026, filed 12 May 2026.